New candidate planetary nebulae in M81

A 34 x 34 arcmin field centred on the spiral galaxy M81 has been searched for emission-line objects using the prime focus wide field camera (WFC) of the 2.54 m Isaac Newton Telescope (La Palma, Spain). A total of 171 candidate planetary nebulae (PNe) are found, 54 of which are in common with the ones detected by Jacoby et al. (1989). The behaviour of PNe excitation as a function of galactocentric distance is examined, and no significant variations are found. The PNe luminosity function is built for the disk and bulge of M81, separately. A distance modulus of 27.92+-0.23 mag is found for disk PNe, in good agreement with previous distance measurements for M81 (Jacoby et al. 1989; Huterer et al. 1995).Comment: 7 pages including 2 tables. A&A accepted; also available at http://www.iac.es/publicaciones/preprints.htm

Spectroscopy of planetary nebulae in M33

Spectroscopic observations of 48 emission-line objects of M33 have been obtained with the multi-object, wide field, fibre spectrograph AF2/WYFFOS at the 4.2m WHT telescope (La Palma, Spain). Line intensities and logarithmic extinction, cbeta, are presented for 42 objects. Their location in the Sabbadin & D'Odorico diagnostic diagram (Halpha/[SII] vs Hlapha/[NII]) suggests that >70% of the candidates are Planetary Nebulae (PNe). Chemical abundances and nebular physical parameters have been derived for the three of the six PNe where the 4363A [OIII] emission line was measurable. These are disc PNe, located within a galactocentric distance of 4.1 kpc, and, to date, they are the farthest PNe with a direct chemical abundance determination. No discrepancy in the Helium, Oxygen and Argon abundances has been found in comparison with corresponding abundances of PNe in our Galaxy. Only a lower limit to the sulphur abundance has been obtained since we could not detect any [SIII] line. N/H appears to be lower than the Galactic value; some possible explanations for this under-abundance are discussed.Comment: 18 pages, 1 JPEG figure and 3 Postscript figures, Accepted for publication in A&

Noise Reduction Interventions in the Urban Environment as a form of Control of Indoor Noise Levels

Abstract Traffic noise is a major problem in all large cities and the sound propagation in the urban context is reinforced by the multiple reflections on the building facades. The surface acoustical characteristics (e.g. referred to roads, pedestrian traffic areas, building facades, building surfaces in general) affect the noise propagation in the urban environment. Through a better outdoor design and management (e.g. by means of green areas, porous asphalt, speed control), or building refurbishment actions (acoustic plaster, absorbing shading devices), the increasing of surface absorption could be useful to mitigate noise environmental pollution and therefore to reduce the sound levels in the proximity of the building facades for their entire height. The reduction of the noise levels outside the buildings would determine lower indoor noise levels and therefore a better situation, without direct actions on the building walls. Through a series of noise propagation calculations in urban environments, by means of a three-dimensional simulation model, the influence of some configurations, and the potential impact of some intervention solutions, will be quantified. In the first stage of the research, the analysis of a simplified model is conducted, to evaluate the influence of noise on the buildings facades, based on a simplified geometry of the urban environment and of the surface acoustic features. The same analysis is validated by means of a more detailed model, corresponding to the configuration of an existing built area, to verify if the analyses performed by means of the simplified model can be extended to more complex layouts. Successively, calculations are developed to quantify the noise levels that occur with different acoustic (absorption of facades, soil, asphalt, or green elements) and geometric (road width, buildings height, presence of balconies, etc.) characteristics, to show the potential reduction given by some interventions. Solutions that can lead to a more significant reduction of the noise in correspondence of the facades are then discussed

Abundances and kinematics for ten anticentre open clusters

Open clusters are distributed all across the disk and are convenient tracers of its properties. In particular, outer disk clusters bear a key role for the investigation of the chemical evolution of the Galactic disk. The goal of this study is to derive homogeneous elemental abundances for a sample of ten outer disk OCs, and investigate possible links with disk structures such as the Galactic Anticenter Stellar Structure. We analyse high-resolution spectra of red giants, obtained from the HIRES@Keck and UVES@VLT archives. We derive elemental abundances and stellar atmosphere parameters by means of the classical equivalent width method. We also performed orbit integrations using proper motions. The Fe abundances we derive trace a shallow negative radial metallicity gradient of slope -0.027+/-0.007 dex.kpc-1 in the outer 12 kpc of the disk. The [alpha/Fe] gradient appears flat, with a slope of 0.006+/-0.007 dex.kpc-1 . The two outermost clusters (Be 29 and Sau 1) appear to follow elliptical orbits. Be 20 also exhibits a peculiar orbit with a large excursion above the plane. The irregular orbits of the three most metal-poor clusters (of which two are located at the edge of the Galactic disk), if confirmed by more robust astrometric measurements such as those of the Gaia mission, are compatible with an inside-out formation scenario for the Milky Way, in which extragalactic material is accreted onto the outer disk. We cannot determine if Be 20, Be 29,and Sau 1 are of extragalactic origin, as they may be old genuine Galactic clusters whose orbits were perturbed by accretion events or minor mergers in the past 5 Gyr, or they may be representants of the thick disk population. The nature of these objects is intriguing and deserves further investigations in the near future.Comment: 17 pages, 9 figures; accepted for publication in A&

Plasma adrenomedullin is associated with short-term mortality and vasopressor requirement in patients admitted with sepsis

Introduction: The incidence of death among patients admitted for severe sepsis or septic shock is high. Adrenomedullin (ADM) plays a central role in initiating the hyperdynamic response during the early stages of sepsis. Pilot studies indicate an association of plasma ADM with the severity of the disease. In the present study we utilized a novel sandwich immunoassay of bioactive plasma ADM in patients hospitalized with sepsis in order to assess the clinical utility.Methods: We enrolled 101 consecutive patients admitted to the emergency department with suspected sepsis in this study. Sepsis was defined by fulfillment of at least two systemic inflammatory response syndrome (SIRS) criteria plus clinical suspicion of infection. Plasma samples for ADM measurement were obtained on admission and for the next four days. The 28-day mortality rate was recorded.Results: ADM at admission was associated with severity of disease (correlation with Acute Physiology and Chronic Health Evaluation II (APACHE II) score: r = 0.46; P <0.0001). ADM was also associated with 28-day mortality (ADM median (IQR): survivors: 50 (31 to 77) pg/mL; non-survivors: 84 (48 to 232) pg/mL; P <0.001) and was independent from and additive to APACHE II (P = 0.02). Cox regression analysis revealed an additive value of serial measurement of ADM over baseline assessment for prediction of 28-day mortality (P < 0.01). ADM was negatively correlated with mean arterial pressure (r = -0.39; P <0.0001), and it strongly discriminated those patients requiring vasopressor therapy from the others (ADM median (IQR): no vasopressors 48 (32 to 75) pg/mL; with vasopressors 129 (83 to 264) pg/mL, P <0.0001).Conclusions: In patients admitted with sepsis, severe sepsis or septic shock plasma ADM is strongly associated with severity of disease, vasopressor requirement and 28-day mortality

The S2N2 metallicity calibrator and the abundance gradient of M 33

We introduce the log(Ha/[SII]6717+6731) vs. log(Ha/[NII]6583) (S2N2) diagnostic diagram as metallicity and ionisation parameter indicator for HII regions in external galaxies. The location of HII regions in the S2N2 diagram was studied both empirically and theoretically. We found that, for a wide range of metallicities, the S2N2 diagram gives single valued results in the metallicity-ionisation parameter plane. We demonstrate that the S2N2 diagram is a powerful tool to estimate metallicities of high-redshift (z ~ 2) HII galaxies. Finally, we derive the metallicity for 76 HII regions in M33 from the S2N2 diagram and calculate an O/H abundance gradient for this galaxy of -0.05 (+-0.01) dex kpc^-1.Comment: 10 pages, 3 figures and 2 tables. Accepted for publication in MNRA

The Local Group Census: planetary nebulae in Sextans B

Five planetary nebulae (PNe) have been discovered in the nearby dwarf irregular galaxy. Emission line images were obtained using the Wide Field Camera of the 2.5m Isaac Newton Telescope (INT) at La Palma (Spain). The candidate PNe were identified by their point-like appearance and relatively strong [OIII] emission-line fluxes. They are located within a galactocentric distance of 2.8 arcmin, corresponding to 1.1 kpc at the distance of Sextans B. Luminosities are in the range 1800--5600Lsolar. Sextans B is one of the smallest dwarf irregular galaxies with a PN population. The number of PNe detected suggest an enhanced star formation rate between 1 and 5 Gyr ago.Comment: 7 pages, 2 figure

Measuring antibiotic availability and use in 20 low- and middle-income countries

Objective To assess antibiotic availability and use in health facilities in low- and middle-income countries, using the service provision assessment and service availability and readiness assessment surveys. Methods We obtained data on antibiotic availability at 13 561 health facilities in 13 service provision assessment and 8 service availability and readiness assessment surveys. In 10 service provision assessment surveys, child consultations with health-care providers were observed, giving data on antibiotic use in 22 699 children. Antibiotics were classified as access, watch or reserve, according to the World Health Organization’s AWaRe categories. The percentage of health-care facilities across countries with specific antibiotics available and the proportion of children receiving antibiotics for key clinical syndromes were estimated. Findings The surveys assessed the availability of 27 antibiotics (19 access, 7 watch, 1 unclassified). Co-trimoxazole and metronidazole were most widely available, being in stock at 89.5% (interquartile range, IQR: 11.6%) and 87.1% (IQR: 15.9%) of health facilities, respectively. In contrast, 17 other access and watch antibiotics were stocked, by fewer than a median of 50% of facilities. Of the 22 699 children observed, 60.1% (13 638) were prescribed antibiotics (mostly co-trimoxazole or amoxicillin). Children with respiratory conditions were most often prescribed antibiotics (76.1%; 8972/11 796) followed by undifferentiated fever (50.1%; 760/1518), diarrhoea (45.7%; 1293/2832) and malaria (30.3%; 352/1160). Conclusion Routine health facility surveys provided a valuable data source on the availability and use of antibiotics in low- and middle-income countries. Many access antibiotics were unavailable in a majority of most health-care facilities

A gas-rich AGN near the centre of a galaxy cluster at z ~ 1.4

The formation of the first virialized structures in overdensities dates back to ~9 Gyr ago, i.e. in the redshift range z ~ 1.4 - 1.6. Some models of structure formation predict that the star formation activity in clusters was high at that epoch, implying large reservoirs of cold molecular gas. Aiming at finding a trace of this expected high molecular gas content in primeval clusters, we searched for the 12CO(2-1) line emission in the most luminous active galactic nucleus (AGN) of the cluster around the radio galaxy 7C 1756+6520 at z ~ 1.4, one of the farthest spectroscopic confirmed clusters. This AGN, called AGN.1317, is located in the neighbourhood of the central radio galaxy at a projected distance of ~780 kpc. The IRAM Plateau de Bure Interferometer was used to investigate the molecular gas quantity in AGN.1317, observing the 12CO(2-1) emission line. We detect CO emission in an AGN belonging to a galaxy cluster at z ~ 1.4. We measured a molecular gas mass of 1.1 x 10^10 Msun, comparable to that found in submillimeter galaxies. In optical images, AGN.1317 does not seem to be part of a galaxy interaction or merger.We also derived the nearly instantaneous star formation rate (SFR) from Halpha flux obtaining a SFR ~65 Msun/yr. This suggests that AGN.1317 is actively forming stars and will exhaust its reservoir of cold gas in ~0.2-1.0 Gyr.Comment: 5 pages, 3 figures, accepted for publication in Astronomy & Astrophysic