IRAC Excess in Distant Star-Forming Galaxies: Tentative Evidence for the 3.3μ\mum Polycyclic Aromatic Hydrocarbon Feature ?

We present evidence for the existence of an IRAC excess in the spectral energy distribution (SED) of 5 galaxies at 0.6<z<0.9 and 1 galaxy at z=1.7. These 6 galaxies, located in the Great Observatories Origins Deep Survey field (GOODS-N), are star forming since they present strong 6.2, 7.7, and 11.3 um polycyclic aromatic hydrocarbon (PAH) lines in their Spitzer IRS mid-infrared spectra. We use a library of templates computed with PEGASE.2 to fit their multiwavelength photometry and derive their stellar continuum. Subtraction of the stellar continuum enables us to detect in 5 galaxies a significant excess in the IRAC band pass where the 3.3 um PAH is expected. We then assess if the physical origin of the IRAC excess is due to an obscured active galactic nucleus (AGN) or warm dust emission. For one galaxy evidence of an obscured AGN is found, while the remaining four do not exhibit any significant AGN activity. Possible contamination by warm dust continuum of unknown origin as found in the Galactic diffuse emission is discussed. The properties of such a continuum would have to be different from the local Universe to explain the measured IRAC excess, but we cannot definitively rule out this possibility until its origin is understood. Assuming that the IRAC excess is dominated by the 3.3 um PAH feature, we find good agreement with the observed 11.3 um PAH line flux arising from the same C-H bending and stretching modes, consistent with model expectations. Finally, the IRAC excess appears to be correlated with the star-formation rate in the galaxies. Hence it could provide a powerful diagnostic for measuring dusty star formation in z>3 galaxies once the mid-infrared spectroscopic capabilities of the James Webb Space Telescope become available.Comment: 25 pages, 4 figures, accepted by Ap

Total Molecular Gas Masses of Planck - Herschel Selected Strongly Lensed Hyper Luminous Infrared Galaxies

We report the detection of CO(1 - 0) line emission from seven Planck and Herschel selected hyper luminous (LIR(8-1000um) > 10^13Lsun) infrared galaxies with the Green Bank Telescope (GBT). CO(1 - 0) measurements are a vital tool to trace the bulk molecular gas mass across all redshifts. Our results place tight constraints on the total gas content of these most apparently luminous high-z star-forming galaxies (apparent IR luminosities of LIR > 10^(13-14) Lsun), while we confirm their predetermined redshifts measured using the Large Millimeter Telescope, LMT (zCO = 1.33 - 3.26). The CO(1 - 0) lines show similar profiles as compared to Jup = 2 -4 transitions previously observed with the LMT. We report enhanced infrared to CO line luminosity ratios of = 110 (pm 22) Lsun(K km s^-1 pc^-2)^-1 compared to normal star-forming galaxies, yet similar to those of well-studied IR-luminous galaxies at high-z. We find average brightness temperature ratios of = 0.93 (2 sources), = 0.34 (5 sources), and = 0.18 (1 source). The r31 and r41 values are roughly half the average values for SMGs. We estimate the total gas mass content as uMH2 = (0.9 - 27.2) x 10^11(alphaCO/0.8)Msun, where u is the magnification factor and alphaCO is the CO line luminosity to molecular hydrogen gas mass conversion factor. The rapid gas depletion times are, on average, tau = 80 Myr, which reveal vigorous starburst activity, and contrast the Gyr depletion timescales observed in local, normal star-forming galaxies.Comment: published in MNRAS, 9pages, 5fig

The Far-Infrared, UV and Molecular Gas Relation in Galaxies up to z=2.5

We use the infrared excess (IRX) FIR/UV luminosity ratio to study the relation between the effective UV attenuation (A_IRX) and the UV spectral slope (beta) in a sample of 450 1<z<2.5 galaxies. The FIR data is from very deep Herschel observations in the GOODS fields that allow us to detect galaxies with SFRs typical of galaxies with log(M)>9.3. Thus, we are able to study galaxies on and even below the main SFR-stellar mass relation (main sequence). We find that main sequence galaxies form a tight sequence in the IRX--beta plane, which has a flatter slope than commonly used relations. This slope favors a SMC-like UV extinction curve, though the interpretation is model dependent. The scatter in the IRX-beta plane, correlates with the position of the galaxies in the SFR-M plane. Using a smaller sample of galaxies with CO gas masses, we study the relation between the UV attenuation and the molecular gas content. We find a very tight relation between the scatter in the IRX-beta plane and the specific attenuation (S_A), a quantity that represents the attenuation contributed by the molecular gas mass per young star. S_A is sensitive to both the geometrical arrangement of stars and dust, and to the compactness of the star forming regions. We use this empirical relation to derive a method for estimating molecular gas masses using only widely available integrated rest-frame UV and FIR photometry. The method produces gas masses with an accuracy between 0.12-0.16 dex in samples of normal galaxies between z~0 and z~1.5. Major mergers and sub-millimeter galaxies follow a different S_A relation.Comment: 11 pages, 6 pages appendix, 11 figures, accepted to Ap

Insights into the effects of N-glycosylation on the characteristics of the VC1 domain of the human receptor for advanced glycation end products (RAGE) secreted by Pichia pastoris

Advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), resulting from non-enzymatic modifications of proteins, are potentially harmful to human health. They directly act on proteins, affecting structure and function, or through receptor-mediated mechanisms. RAGE, a type I transmembrane glycoprotein, was identified as a receptor for AGEs. RAGE is involved in chronic inflammation, oxidative stress-based diseases and ageing. The majority of RAGE ligands bind to the VC1 domain. This domain was successfully expressed and secreted by Pichia pastoris. Out of two N-glycosylation sites, one (Asn25) was fully occupied while the other (Asn81) was under-glycosylated, generating two VC1 variants, named p36 and p34. Analysis of N-glycans and of their influence on VC1 properties were here investigated. The highly sensitive procainamide labeling method coupled to ES-MS was used for N-glycan profiling. N-glycans released from VC1 ranged from Man9GlcNAc2- to Man15GlcNAc2- with major Man10GlcNAc2- and Man11GlcNAc2- species for p36 and p34, respectively. Circular dichroism spectra indicated that VC1 maintains the same conformation also after removal of N-glycans. Thermal denaturation curves showed that the carbohydrate moiety has a small stabilizing effect on VC1 protein conformation. The removal of the glycan moiety did not affect the binding of VC1 to sugar-derived AGE- or malondialdehyde-derived ALE-human serum albumin. Given the crucial role of RAGE in human pathologies, the features of VC1 from P. pastoris will prove useful in designing strategies for the enrichment of AGEs/ALEs from plasma, urine or tissues, and in characterizing the nature of the interaction

Herschel Far-IR counterparts of SDSS galaxies: Analysis of commonly used Star Formation Rate estimates

We study a hundred of galaxies from the spectroscopic Sloan Digital Sky Survey with individual detections in the Far-Infrared Herschel PACS bands (100 or 160 $\mu$m) and in the GALEX Far-UltraViolet band up to z$\sim$0.4 in the COSMOS and Lockman Hole fields. The galaxies are divided into 4 spectral and 4 morphological types. For the star forming and unclassifiable galaxies we calculate dust extinctions from the UV slope, the H$\alpha$/H$\beta$ ratio and the $L_{\rm IR}/L_{\rm UV}$ ratio. There is a tight correlation between the dust extinction and both $L_{\rm IR}$ and metallicity. We calculate SFR$_{total}$ and compare it with other SFR estimates (H$\alpha$, UV, SDSS) finding a very good agreement between them with smaller dispersions than typical SFR uncertainties. We study the effect of mass and metallicity, finding that it is only significant at high masses for SFR$_{H\alpha}$. For the AGN and composite galaxies we find a tight correlation between SFR and L$_{IR}$ ($\sigma\sim$0.29), while the dispersion in the SFR - L$_{UV}$ relation is larger ($\sigma\sim$0.57). The galaxies follow the prescriptions of the Fundamental Plane in the M-Z-SFR space.Comment: 24 pages, 23 figures, accepted for publication in MNRA

ISM conditions in z~0.2 Lyman-Break Analogs

We present an analysis of far--infrared (FIR) [CII] and [OI] fine structure line and continuum observations obtained with $Herschel$/PACS, and CO(1-0) observations obtained with the IRAM Plateau de Bure Interferometer, of Lyman Break Analogs (LBAs) at $z\sim 0.2$. The principal aim of this work is to determine the typical ISM properties of $z\sim 1-2$ Main Sequence (MS) galaxies, with stellar masses between $10^{9.5}$ and $10^{11}$ $M_{\odot}$, which are currently not easily detectable in all these lines even with ALMA and NOEMA. We perform PDR modeling and apply different IR diagnostics to derive the main physical parameters of the FIR emitting gas and dust and we compare the derived ISM properties to those of galaxies on and above the MS at different redshifts. We find that the ISM properties of LBAs are quite extreme (low gas temperature, high density and thermal pressure) with respect to those found in local normal spirals and more active local galaxies. LBAs have no [CII] deficit despite having the high specific star formation rates (sSFRs) typical of starbursts. Although LBAs lie above the local MS, we show that their ISM properties are more similar to those of high-redshift MS galaxies than of local galaxies above the main sequence. This data set represents an important reference for planning future ALMA [CII] observations of relatively low-mass MS galaxies at the epoch of the peak of the cosmic star formation.Comment: 19 pages, 12 Figures,8 Tables, Accepted for publication in A&