Функция ионных каналов эпителиальных клеток при муковисцидозе

Cystic fibrosis is a systemic hereditary disease caused by mutations in the CFTR gene, which regulates the transport of electrolytes (mainly chloride) across the membranes of the epithelial cells that line excretory ducts of exocrine glands. Dysfunction of the CFTR protein reduces passage of chloride ions through cell membranes and disrupts the passage of sodium ions, bicarbonate ions, and water.The aim of the study was to analyze comprehensively functioning of chloride and alternative (sodium and calcium) channels in the epithelium of patients with cystic fibrosis in relation to the age using functional tests in vitro.Methods. We used data from medical histories of patients with cystic fibrosis and intestinal current measurements.Results. The function of the calcium channel decreased with age in people without cystic fibrosis and carriers of “severe” genotypes. The function of sodium, chloride, and calcium channels was lower in all age groups of patients with cystic fibrosis compared to controls (p < 0.05). When comparing groups of patients with “severe genotype” and “mild genotype”, statistically significant differences were found in response to forskolin (p < 0.05). Patients with “mild” genotypes had a residual function of the CFTR channel which decreased with age.Conclusion. For the first time, the functioning of chloride and alternative channels in cystic fibrosis have been described in relation to the age and the genotype of patients.Муковисцидоз (МВ) – системное наследственное заболевание, обусловленное мутациями в гене CFTR, который регулирует транспорт электролитов (главным образом хлора) через мембраны эпителиальных клеток, выстилающих выводные протоки экзокринных желез. Нарушение функции белка CFTR приводит к снижению пассажа ионов хлора через мембраны клеток и нарушению пассажа ионов натрия, бикарбонат-ионов, воды.Целью исследования явилось комплексное изучение функционирования хлорного и альтернативных (натриевых и кальциевых) каналов эпителия у пациентов с МВ в возрастном аспекте с использованием функциональных тестов in vitro.Материалы и методы. Использованы данные историй болезни пациентов с МВ и метод определения разницы кишечных потенциалов.Результаты. Установлено, что с возрастом снижается функция кальциевого канала у людей без МВ и носителей «тяжелых» генотипов при МВ. Функция натриевого, хлорного, кальциевого каналов ниже во всех возрастных группах у пациентов с МВ по сравнению с таковой у лиц контрольной группы (р < 0,05). При сравнении групп пациентов с «тяжелым» и «мягким» генотипами выявлены статистически значимые различия в ответ на применение форсколина (р < 0,05), при «мягких» генотипах действует остаточная функция CFTR-канала, которая снижается с возрастом.Заключение. Впервые описаны особенности функционирования хлорного и альтернативных каналов в возрастном аспекте при МВ с учетом генотипа пациентов

Effect of benzoyl taurine dipotassium salt on coagulation, hemostasis and vascular activity in the microvasculature of the brain in violation of cerebral circulation

Cerebral circulation disorders (CCD) are one of the most common causes of mortality and disability in the population. Improving the microcirculation of brain tissue is one of the main directions in the treatment and prevention of CCD.Aim of the study was to evaluate the effect of a new derivative of hydroxybenzoic (salicylic) acid on neurological deficit, hemostasis and functional state of arterial pial vessels in the study of prostacyclin-synthetic activity and evaluation of NOmediated endothelial dysfunction in rats under experimental CCD conditions. Material and methods. The experiment was carried out on 50 Wistar rats, which were simulated for CCD by occlusion of common carotid arteries. Within 7 days after the operation, the animals received treatment according to the group: saline, C-60 (N-(3-hydroxybenzoyl)taurine dipotassium salt) and acetylsalicylic acid. After treatment, the activity of the prostacyclin-synthetic system was assessed by the reaction of pial vessels to indomethacin, endothelial dysfunction was estimated by tests with acetylcholine and L-NAME. The parameters of plasma and platelet hemostasis were also studied, and behavioral tests (open field, adhesion test, rotarod, Morris water maze, passive avoidance task) were used to assess neurological deficits in animals. Results. When studying the level of neurological deficit in animals with brain ischemia after a course of administration of the test compound, it was noted that in the treated groups, compared with the control group, there was a significant increase in motor and exploratory activity, improvement in sensory-motor function and coordination of movements (p < 0.05). Also, in the group treated with the salicylic acid derivative, normalization of the parameters of platelet and plasma hemostasis, improvement of the functional state of the vascular endothelium was observed. According to the results of assessing the prostacyclin-synthesizing activity of the endothelium of the cerebral vessels, it follows that the test compound inhibits cyclooxygenase at a level comparable with effect of acetylsalicylic acid. Conclusions. A new derivative of salicylic acid, the dipotassium salt of N-(3-hydroxybenzoyl)taurine, reduces the severity of neurological deficit, improves hemostasis parameters and the functional state of cerebral vessels in rats with brain ischemia in the experiment

Prehospital Period in Patients with COVID-19: Cardiovascular Comorbidity and Pharmacotherapy During the First Epidemic Wave (Hospital Registry Data)

Aim. Based on the data from the register of patients with COVID-19 and community-acquired pneumonia (CAP), analyze the duration of the prehospital period, cardiovascular comorbidity and the quality of prehospital pharmacotherapy of concomitant cardiovascular diseases (CVD).Material and methods. Patients were included to the study which admitted to the FSBI "NMHC named after N.I. Pirogov" of the Ministry of Health of the Russian Federation with a suspected or confirmed diagnosis of COVID-19 and/or CAP. The data for prehospital therapy, information from medical histories and a patients’survey in the hospital or by telephone contact 1-2 weeks after discharge were study. The duration of the prehospital stage was determined from the date of the appearance of clinical symptoms of coronavirus infection to the date of hospitalization.Results. The average age of the patients (n=1130; 579 [51.2%] men and 551 [48.8%] women) was 57.5±12.8 years. The prehospital stage was 7 (5,0; 10,0) days and did not differ significantly in patients with the presence and absence of CVD, but was significantly less in the deceased than in the surviving patients, as well as in those who required artificial lung ventilation (ALV). 583 (51.6%) patients had at least one CVD. Cardiovascular comorbidity was registered in 222 (42.7%) patients with hypertension, 210 (95.5%) patients with coronary heart disease (CHD), 104 (91.2%) patients with atrial fibrillation (AF). The inclusion of non-cardiac chronic diseases in the analysis led to an increase in the total proportion of patients with concomitant diseases to 65.8%. Approximately a quarter of hypertensive patients did not receive antihypertensive therapy, a low proportion of patients receiving antiplatelet agents and statins for CHD was revealed – 53% and 31.8%, respectively, anticoagulants for AF – 50.9%.Conclusion. The period from the onset of symptoms to hospitalization was significantly shorter in the deceased than in the surviving patients, as well as in those who required ALV. The proportion of people with a history of at least one CVD was about half of the entire cohort of patients. In patients with CVD before COVID-19 disease, a low frequencies of prescribing antihypertensive drugs, statins, antiplatelet agents and anticoagulants (in patients with AF) were recorded at the prehospital stage

Detection and Treatment of Hyperuricemia in Clinical Practice (According to the PROFILE Outpatient Registry)

Aim. To study the frequency of detection of hyperuricemia (HU) in patients with high and very high cardiovascular risk and the frequency of prescribing drugs that lower serum uric acid (sUA) levels in real clinical practice.Material and methods: The general information of the study was based on the data of 2457 patients who were consistently included in the «PROFILE» registry until November 30, 2020: 1250 men (50.9%) and 1207 (49.1%) women. All patients with HU were selected (UA level ≥360 pmol/l in women, ≥420 pmol/l in men). At the stage of inclusion of the patient, data on MC indicators were available in 1777 (72.3%), upon re-examination - only 262 (33.2%) out of 790 patients who returned to the appointment.Results: The most common study of the level of sUA was performed in patients with gout (65.2%), with arterial hypertension (AH) and dyslipemia in 29.1% of cases, with diabetes mellitus (DM) - 30.1%, with impaired tolerance to glucose (IGT) - 40.2%, with other diseases, the proportion of patients with a known UA was even less. A positive relationship was found between the presence of AH and IGT with the frequency of UA control (p<0.001). In patients with AH, an increase in the level of sUA was detected significantly more often than in patients without AH (p<0.001), and less frequently in patients with DM and IGT (p<0.001 and p<0.01, respectively). The frequency of allopurinol prescribing was low: 49 (2%) patients received therapy, while of the 284 patients with HU, only 20 (7%) were prescribed allopurinol.Conclusion: in real clinical practice, only 29.1% of patients with AH and 20-25% of patients with other CVDs were monitored for sUA levels, every third patient had data on sUA levels at a repeat visit. In the presence of gout, the proportion of patients with current UA was higher (65%). For those with AH and IGT, positive correlations were found between the presence of the disease and control of sUA levels. A low frequency of prescribing drugs for the correction of HU was revealed

Macronyssus granulosus

Macronyssus granulosus (Kolenati, 1856) Dermanissus [sic] granulosus Kolenati, 1856: 20. Dermanissus [sic] glutinosus Kolenati, 1856: 20. Lepronyssus granulosus.— Kolenati, 1858: 6; Fonseca, 1948: 307. Lepronyssus glutinosus.— Kolenati, 1858: 6. Lepronyssus leprosus Kolenati, 1858: 5 (synonymy by Radovsky, 1966). Liponyssus granulosus.— Hirst, 1921: 794. Hirstesia transvaalensis Zumpt, 1950: 89 (synonymy by Radovsky, 1966). Hirstesia transvaalensis.— Keegan, 1956: 213. Bdellonyssus pollerae Lombardini, 1957: 284 (synonymy by Radovsky, 1966). Ichoronyssus pollerae.— Wen, 1975: 351. Ichoronyssus leprosus.—Strandtmann & Warton, 1958: 91. Ichoronyssus granulosus.— Vshivkov, 1963: 324; Costa, 1967: 107; Dubovchenko, 1968: 8; Pinchuk, 1970: 73. Macronyssus granulosus.— Radovsky, 1966: 94; 1967: 132; Beron, 1968: 159; 1974: 65; Uchikawa, 1976: 841; Ogadzhanyan & Arutyunyan, 1974: 79; Cicolani & Manilla, 1980: 35; Rybin, 1983: 356; Rybin et al., 1989: 425; Whitaker et al., 1990: 54; Estrada-Peña & Serra-Cobo, 1991: 345; Lourenço & Palmeirim, 2007: 163; Radovsky, 2010: 56. Type locality: Banat (Romania) (Kolenati, 1856). Type host: Miniopterus schreibersi (Kolenati, 1856). Distribution in Russian Federation: Crimea (as Ichoronyssus granulosus — Vshivkov, 1963; Stanyukovich, 1997; Orlova & Orlov, 2018), Voronezh Province (Stanyukovich, 1997), Krasnoyarsk Region (Stanyukovich, 1997), Altai Republic (Orlova & Orlov, 2015; Orlova et al., 2015c), Primorskiy Region (Medvedev et al., 1991; Tiunov et al., 2021), Sakhalin Province (Kunashir island) (Orlova & Zhigalin, 2015a; Orlova et al., 2015b), [Far East] (Stanyukovich, 1997). Distribution outside Russian Federation: Eurasia (Radovsky, 1967); Africa (Radovsky, 1967). Hosts. Myotis blythii (Vshivkov, 1963; Stanyukovich, 1997; Orlova & Orlov, 2018), M. myotis (Radovsky, 1967), M. macrodactylus (Stanyukovich, 1997; present paper), M. petax (as M. daubentonii — Medvedev et al., 1991), M. sibiricus (as M. brandtii — Medvedev et al., 1991) M. nattereri (Stanyukovich, 1997), M. dasycneme (Stanyukovich, 1997), M. daubentonii (Stanyukovich, 1997), M. brandtii (Stanyukovich, 1997), M. mystacinus (Stanyukovich, 1997), M. emarginatus E. Geoffroy, 1806 (Vshivkov, 1963), M. cappaccinii (Stanyukovich, 1997), M. tricolor (Radovsky, 1967), Barbastella barbastellus (Stanyukovich, 1997), Pipistrellus javanicus (Beron, 2014), Plecotus auritus (Stanyukovich, 1997), Murina leucogaster (Stanyukovich, 1997), Nyctalus leisleri (Stanyukovich, 1997), Miniopterus fuliginosus (as M. schreibersi — Medvedev et al., 1991), Mi. schreibersi (Dusbábek, 1964), Mi. fraterculus Thomas & Schwann, 1906 (Radovsky, 1967), Rhinolophus clivosus Cretzschmar, 1828 (Radovsky, 1967), Rh. euryale (Radovsky, 1967), Rosettus lanosus Thomas, 1906 (Radovsky, 1967). Ro. aegyptiacus (E. Geoffroy, 1810) (Beron, 2014).Published as part of Orlova, M. V., Klimov, P. B., Orlov, O. L., Smirnov, D. G., Zhigalin, A. V., Budaeva, I. V., Emelyanova, A. A. & Anisimov, N. V., 2021, A checklist of bat-associated macronyssid mites (Acari: Gamasina: Macronyssidae) of Russia, with new host and geographical records, pp. 537-564 in Zootaxa 4974 (3) on pages 547-548, DOI: 10.11646/zootaxa.4974.3.4, http://zenodo.org/record/477806

Macronyssus ellipticus

Macronyssus ellipticus (Kolenati, 1856) Caris ellipticus Kolenati, 1856: 16. Liponyssus ellipticus.— Hirst, 1922: 795. Ichoronyssus mohrae Vitzthum, 1932: 32 (synonymy by Radovsky, 1966). Ichoronyssus ellipticus.— Pinchuk, 1970: 82. Macronyssus ellipticus.—Fonseca, 1941: 263; Radovsky, 1966: 94; 1967: 128; Beron, 1968: 159; Haitlinger, 1978: 707; Haitlinger & Ruprecht, 1985: 616; Baker & Beccaloni, 2006: 173; Scheffler, 2010; Radovsky, 2010: 56. Type locality: unknown. Type host: Myotis myotis (Kolenati, 1856). Material. F, 4 N1 ex Natterer’s bat Myotis nattereri, from Staritsa, 29 February 2020, leg. O.L. Orlov, A.A. Emelyanova; 9 N1 ex Myotis nattereri, N1 ex Myotis mystacinus, 3 N1 ex Myotis brandtii, from Samara, 25 November 2001, leg. D.G. Smirnov; N1 ex M. brandtii, M ex Plecotus auritus, 5 N1 ex M. daubentonii, 4 N1 ex M. dasycneme, from SNR “Samarskaya Luka”, 1-31 May 2005 leg. D.G. Smirnov. Distribution in Russian Federation: Leningrad Province (Stanyukovich, 1990a; Orlova et al., 2015d), Tver Province (present paper), Samara Province (present paper), Northern Osetiya Republic (Stanyukovich, 1997), Sverdlovsk Province (Orlova, 2011), Chelyabinsk Province (Orlova & Orlov, 2013), Altai Region (Orlova et al., 2017a), Primorskiy Region (Tiunov et al., 2021), [Far East] (Stanyukovich, 1997), [Urals, Altai] (Orlova et al., 2015d). Distribution outside Russian Federation: Europe (Radovsky, 1967), Central Asia (Stanyukovich, 1997). Hosts. Myotis myotis (Radovsky, 1967), M. blythii (Radovsky, 1967), M. brandtii (Orlova, 2011), M. dasycneme (Stanyukovich, 1990a), M. daubentonii (Stanyukovich, 1990a), M. nattereri (Stanyukovich, 1997; present paper), M. brandtii (Stanyukovich, 1990a), M. macrodactylus (present paper), M. mystacinus (Orlova & Orlov, 2013), Vespertilio murinus (Beron, 2014), Plecotus auritus (Orlova & Orlov, 2013), Murina hilgendorfi (as M. leucogaster — Stanyukovich, 1997), Rhinolophus ferrumequinum (Radovsky, 1967), Rh. hipposideros (Radovsky, 1967), Miniopterus schreibersi (Beron, 2014).Published as part of Orlova, M. V., Klimov, P. B., Orlov, O. L., Smirnov, D. G., Zhigalin, A. V., Budaeva, I. V., Emelyanova, A. A. & Anisimov, N. V., 2021, A checklist of bat-associated macronyssid mites (Acari: Gamasina: Macronyssidae) of Russia, with new host and geographical records, pp. 537-564 in Zootaxa 4974 (3) on page 546, DOI: 10.11646/zootaxa.4974.3.4, http://zenodo.org/record/477806

Macronyssus crosbyi

Macronyssus crosbyi (Ewing & Stover, 1915) Liponyssus crosbyi Ewing & Stover, 1915: 109. Leiognathus crosbyi.— Ewing, 1923: 7. Ichoronyssus hasei Vitzthum, 1932: 23 (synonymy by Radovsky, 1966). Ichoronyssus kolenatii Fonseca, 1948: 280 (synonymy by Radovsky, 1966). Ichoronyssus crosbyi.— Fonseca, 1948: 299; Yunker & Radovsky, 1966: 98. Ichoronyssus britanicus.— Furman, 1950: 480 (misidentification). Ichoronyssus quadridentatus Strandtmann & Hunt, 1951: 462; Baker & Strandtmann, 1959: 225 (synonymy by Radovsky, 1966). Macronyssus crosbyi.— Radovsky, 1966: 94; 1967: 119; Anciaux de Faveaux, 1971: 52; Hoffmann et al., 1972: 153; Whitaker, 1973: 1149; Yunker et al., 1975: 252; Whitaker et al., 1983; Whitaker & Maser, 1985: 73; Stanjukovich, 1990: 197; Ritzi et al., 2001: tabl.; Reeves et al., 2007: 53; Jaunbauere et al., 2008: 40; Radovsky, 2010: 56. Type locality: Rockport, Missouri (Ewing & Stover, 1915). Type host: “ Vesper subulatus ” (Ewing & Stover, 1915). Material. M ex soprano pipistrelle Pipistrellus pygmaeus Leach, 1825 from biological station “Venevitinovo”, 4 June 2019, leg. O.L. Orlov, I. V. Budaeva. Distribution in Russian Federation: Karelia Republic (Lebedeva et al., 2020), Voronezh Province (present paper), Krasnoyarsk Region (Orlova et al., 2017a), Irkutsk Province (Orlova et al., 2017a), Buryatiya Republic (Orlova et al., 2017a), Yakutiya Republic (Orlova et al., 2017a), Khabarovsk Region (Medvedev et al., 1991), Magadan Province (Medvedev et al., 1991), [Urals, Altai, Russian Far East— Orlova et al., 2015d]. Distribution outside Russian Federation: Europe (Baltic states— Stanyukovich, 1990a; Jaunbauere et al., 2008), North and South America (Radovsky, 1967; Hoffmann et al., 1972; Presley 2004). Hosts (Old World): Eptesicus nilssonii (Stanyukovich, 1990a; Lebedeva et al., 2020), Myotis daubentonii (Stanyukovich, 1990a), M. dasycneme (Stanyukovich, 1990a), M. mystacinus (Stanyukovich, 1990a), M. sibiricus (Orlova et al., 2017a), M. brandtii (Stanyukovich, 1990a), Pipistrellus nathusii (Stanyukovich, 1990a), Pipistrellus pygmaeus (present paper), Vespertilio murinus (Stanyukovich, 1990a), Plecotus ognevi (as Pl. auritus) (Medvedev et al., 1991).Published as part of Orlova, M. V., Klimov, P. B., Orlov, O. L., Smirnov, D. G., Zhigalin, A. V., Budaeva, I. V., Emelyanova, A. A. & Anisimov, N. V., 2021, A checklist of bat-associated macronyssid mites (Acari: Gamasina: Macronyssidae) of Russia, with new host and geographical records, pp. 537-564 in Zootaxa 4974 (3) on pages 544-545, DOI: 10.11646/zootaxa.4974.3.4, http://zenodo.org/record/477806

Macronyssus flavus

Macronyssus flavus (Kolenati, 1856) Dermanissus [sic] flavus Kolenati, 1856: 19. ? Dermanissus lobatus Kolenati, 1856: 20. Liponyssus lobatus.— Kolenati, 1856: 22; Porta, 1914: 481. Lepronyssus flavus.— Kolenati, 1858: 6; Fonseca, 1948: 306; Turk, 1953: 13; Bogdanov, 1953: 31. Lepronyssus lobatus.— Kolenati, 1858: 6; Turk, 1953: 13. Liponyssus flavus.— Hirst 1922: 791. Ichoronyssus britannicus Fonseca, 1948: 299 (synonymy by Radovsky, 1966). Ichoronyssus flavus.— Arzamasov & Kurskov, 1962: 203; Vshivkov, 1963: 324; Bregetova, 1953: 330; Morozova et al., 1964: 162; Dusbábek, 1964a: 81; 1966: 44; Zemskaya, 1965: 316; Dubovchenko, 1968: 8; Pinchuk, 1970: 73; Mahnert, 1971: 926. Macronyssus flavus.— Evans et al., 1961: 140; Radovsky, 1966: 94; 1967: 131; Juvara, 1967: 187; Beron, 1968: 159; Uchikawa, 1976: 841; Rybin, 1983: 357; Rybin et al., 1989: 425; Baker & Beccaloni, 2006: 173; Haitlinger & Lupicky, 2008: 124; Radovsky, 2010: 56. Type locality: Czech Republic (“Böhmen, Mähren ”) (Kolenati, 1856). Type host: Nyctalus noctula (Kolenati, 1856). Material. N1 ex Nyctalus noctula from Akhshtyrskaya cave, 1-31 August 2001, leg. D.G. Smirnov; 2 MM, N1 ex Nyctalus noctula from NP “Nurgush”, 24 June 2006, leg. D.G. Smirnov; 2 FF, 9 N1 ex N. noctula from Mordovskiy State Natural Reserve, 21 June 2016, leg. D.G. Smirnov; 6 FF, 3 MM, 5 N1 ex N. noctula from Shaytan-Kazak, 19 May 2019, leg. D.G. Smirnov, A.M. Lukyanenko; N1 ex Pipistrellus pipistrellus from neighborhood of Khasavyurt town, 20 May 2019, leg. D.G. Smirnov, A.M. Lukyanenko; 18 FF, 10 N1, N2 ex N. noctula from State Nature Reserve “Samarskaya Luka”, 1-31 June 2006, leg. D.G. Smirnov; 6 FF, M, N2 ex N. leisleri from SNR “Samarskaya Luka”, 1-31 June 2006, leg. D.G. Smirnov; 42 FF, 2 MM, 203 N1, 7 N2 ex N. lasiopterus from SNR “Samarskaya Luka”, 25 July 2006, leg. D.G. Smirnov; 5 FF ex Myotis daubentonii from SNR “Samarskaya Luka”, 1-31 November 2005, leg. D.G. Smirnov; F, M ex Myotis daubentonii from SNR “Samarskaya Luka”, 1-31 July 2006, leg. D.G. Smirnov; 4 MM, 5 N1 ex Eptesicus serotinus from Biological station “Venevitinovo”, 17 June 2019, leg. I. V. Budaeva. Distribution in Russian Federation: Crimea (as Ichoronyssus flavus — Bregetova, 1956; Vshivkov, 1963; Stanyukovich, 1997), Pskov Province (Medvedev et al., 2000), Leningrad Province (Bregetova, 1956; Stanyukovich, 1997), Penza Province (Stanyukovich, 1997), Voronezh Province (present paper), Nizhniy Novgorod Province (Stanyukovich, 1997), Samara Province (Stanyukovich, 1997; present paper), Volgograd Province (Bregetova, 1956; Stanyukovich, 1997), Rostov Province (Zabashta et al., 2019), Krasnodar Region (present paper), Dagestan Republic (present paper), Kirov Province (present paper), Udmurtia Republic (Orlova et al., 2011), Khabarovsk Region (Bregetova, 1956; as Far East— Stanyukovich, 1997). Distribution outside Russian Federation: Europe (Radovsky, 1967). Asia (Stanyukovich, 1997). Hosts. Nyctalus noctula (Vshivkov, 1963; Stanyukovich, 1997; Medvedev et al., 2000; present paper), N. leisleri (Kuhl, 1817) (Stanyukovich, 1997; present paper), N. lasiopterus (Schreber, 1780) (Stanyukovich, 1997; present paper), Myotis daubentonii (Stanyukovich, 1997), M. myotis (Stanyukovich, 1997), M. blythii (Stanyukovich, 1997), M. mystacinus (Stanyukovich, 1997), M. nattereri (Stanyukovich, 1997), Pipistrellus pipistrellus (Vshivkov, 1963; Stanyukovich, 1997; present paper), P. nathusii (Stanyukovich, 1997; Medvedev et al., 2000), Vespertilio murinus (Stanyukovich, 1997), Eptesicus nilssonii (Stanyukovich, 1997), Ep. serotinus (Beron, 2014), Eptesicus bottae ognevi Bobrinskoy, 1918 (Beron, 2014), Barbastella barbastellus (Dusbábek, 1964), Rhinolophus ferrumequinum (Vshivkov, 1963).Published as part of Orlova, M. V., Klimov, P. B., Orlov, O. L., Smirnov, D. G., Zhigalin, A. V., Budaeva, I. V., Emelyanova, A. A. & Anisimov, N. V., 2021, A checklist of bat-associated macronyssid mites (Acari: Gamasina: Macronyssidae) of Russia, with new host and geographical records, pp. 537-564 in Zootaxa 4974 (3) on page 547, DOI: 10.11646/zootaxa.4974.3.4, http://zenodo.org/record/477806

Macronyssus corethroproctus

Macronyssus corethroproctus (Oudemans, 1902) Liponyssus corethroproctus Oudemans, 1902: 15. Macronyssus corethroproctus (Oudemans).— Buitendijk, 1945: 306; Radovsky, 1966: 94; 1967: 117; 2010: 56; Beron, 1969: 160; Haitlinger, 1978: 712. Type locality: Sneek (Netherlands) (Oudemans, 1902). Type host: Myotis dasycneme (Oudemans, 1902). Material. 3 FF, 31 N1 ex pond bat Myotis dasycneme, 1-31 November 2005, N1 ex Myotis mystacinus, 25 November 2001, 4 N1 from Natterer’s bat Myotis nattereri, from State Nature Reserve “Samarskaya Luka”, 25 November 2001, leg. D.G. Smirnov; F ex Eptesicus nilssonii, from Kuminskiy settlement, 7 August 2008, leg. K. V. Bernikov; 2 N1 ex Myotis dasycneme, from Mordovian State Natural Reserve, 23 June 2016, leg. D.G. Smirnov; 2 N1 ex Pipistrellus nathusii from Pogromnoye settlement 26 June 2003, leg. D.G. Smirnov; F ex Myotis dasycneme, from Barsukovskaya cave, 8 November 2013, leg. A. V. Zhigalin. Distribution in Russian Federation: Leningrad Province (Stanyukovich, 1997; Orlova et al., 2014), Penza Province (Stanyukovich, 1997), Samara Province (present paper), Mordovia Republic (present paper), Stavropol Region (Stanyukovich, 1997), Udmurtiya Republic (Orlova et al., 2011), Bashkiriya Republic (Orlova et al., 2014; Orlova & Orlov, 2013), Orenburg Province (present paper), Sverdlovsk Province (Orlova et al., 2012; Vinarskaya & Orlova, 2012), Chelyabinsk Province (Orlova et al., 2014), Khanty-Mansi Autonomous Region (Orlova et al., 2014; Orlova & Tomishina, 2019; present paper), Altai Region (Orlova et al., 2014), Novosibirsk Province (present paper), [Urals, Western Siberia— Orlova et al., 2015d]. Distribution outside Russian Federation: Europe (Radovsky, 1967). Hosts. Myotis dasycneme (Stanyukovich, 1997; Orlova et al., 2011; Orlova et al., 2012; Orlova et al., 2012; Vinarskaya & Orlova, 2012; Orlova et al., 2014), Myotis blythii (Beron, 2014) Myotis daubentonii (Orlova et al., 2011), Myotis nattereri (present paper), Myotis mystacinus (Orlova & Orlov, 2013; present paper), Myotis brandtii (present paper), Pipistrellus nathusii (Stanyukovich, 1997; present paper), Eptesicus nilssonii (present paper), Vespertilio murinus (Stanyukovich, 1997).Published as part of Orlova, M. V., Klimov, P. B., Orlov, O. L., Smirnov, D. G., Zhigalin, A. V., Budaeva, I. V., Emelyanova, A. A. & Anisimov, N. V., 2021, A checklist of bat-associated macronyssid mites (Acari: Gamasina: Macronyssidae) of Russia, with new host and geographical records, pp. 537-564 in Zootaxa 4974 (3) on page 544, DOI: 10.11646/zootaxa.4974.3.4, http://zenodo.org/record/477806

Steatonyssus noctulus Rybin 1992

Steatonyssus noctulus Rybin, 1992 Steatonyssus noctulus Rybin, 1992: 157. Steatonyssus noctulus.—Rybin, 1995: 47; Rupp & Ludwig, 2000: 275; Baker & Craven, 2003: 6; Radovsky, 2010: 101. Type locality: Osh, Oshskaya province (Kirghizstan). Type host: Nyctalus noctula. Material. 2 FF, 21 N1 ex Eptesicus serotinus from Biological station “Venevitinovo”, 17 June 2019, leg. I. V. Budaeva; M ex Nyctalus lasiopterus from State Nature Reserve “Samarskaya Luka”, 7 July 2016, leg. D.G. Smirnov; N1 ex Nyctalus leisleri from SNR “Samarskaya Luka”, 8 July 2016, leg. D.G. Smirnov. Distribution in Russian Federation: Crimea (Stanyukovich, 1997), Pskov Province (Medvedev et al., 2000), Penza Province (Stanyukovich, 1997), Voronezh Province (present paper), Samara Province (present paper), Rostov Province (Zabashta et al., 2019), Dagestan Republic (Orlova et al., 2020a), [Russia] (Orlova et al., 2015d). Distribution outside Russian Federation: Europe (Stanyukovich, 1997; Rupp & Ludwig 2000). Asia (Rybin 1992; Stanyukovich, 1997). Hosts. Nyctalus noctula (Stanyukovich, 1997; Medvedev et al., 2000; Zabashta et al., 2019), Ny. lasiopterus (present paper), Ny. leisleri (present paper), Miniopterus schreibersi (Stanyukovich, 1997); Eptesicus serotinus (present paper).Published as part of Orlova, M. V., Klimov, P. B., Orlov, O. L., Smirnov, D. G., Zhigalin, A. V., Budaeva, I. V., Emelyanova, A. A. & Anisimov, N. V., 2021, A checklist of bat-associated macronyssid mites (Acari: Gamasina: Macronyssidae) of Russia, with new host and geographical records, pp. 537-564 in Zootaxa 4974 (3) on page 551, DOI: 10.11646/zootaxa.4974.3.4, http://zenodo.org/record/477806