Evaluation of a coupled hydrodynamic-closed ecological cycle approach for modelling dissolved oxygen in surface waters

The description of intertwined ecological processes in surface waters requires a holistic approach that accounts for spatially distributed hydrological/water quality processes. This study describes a new approach to model dissolved oxygen (DO) based on linked hydrodynamic and closed nutrient cycle ecological models. Long term datasets from the River Dommel (Netherlands) are used to determine: 1) if this methodology is suitable for modelling DO concentrations, 2) the model sensitivity to various levels of nutrients input, and 3) the DO production and consumption processes and their response to nutrient input changes. Results show that seasonal dynamics of DO are well quantified at long timescales; the sensitivity of DO to different pollutant sources exhibits significant seasonal variation and the largest influences on DO are aeration and mineralization of organic material. The approach demonstrates an ability to consider the impacts of nutrient input and long term vegetation maintenance on ecological quality

Thermodynamic Properties of the Incommensurate Phase of CuGeO_3

We present high resolution measurements of the specific heat and the thermal expansion of the inorganic spin--Peierls cuprate CuGeO_3 in a magnetic field of 16 Tesla. At the transition from the incommensurate to the uniform phase both quantities show pronounced anomalies, which allow to derive the uniaxial pressure dependencies of the transition temperature. In high magnetic fields the specific heat is dominated by magnetic excitations and follows a T^3 law at low temperatures. The thermal expansion measurements show the occurrence of spontaneous strains along all three lattice constants and yield high resolution measurements of the temperature dependence of the incommensurate structural distortion. The sizes of the spontaneous strains in the incommensurate phase are significantly reduced, but both their anisotropy as well as their temperature dependencies are very similar to those in zero field.Comment: 12 pages (Latex), 4 Figs. (PS), to appear in Phys. Rev. B54 (Vol.21

The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

The leukemia-associated Mllt10/Af10 and its partner the histone methyltransferase Dot1l are identified as Tcf4/β-catenin co-activators and shown to be essential for Wnt-driven endogenous gene expression, intestinal development and homeostasis