Characterization and In Silico Analysis of Pregnancy-Associated Glycoprotein-1 Gene of Buffalo (Bubalus bubalis)

Pregnancy-Associated Glycoproteins (PAGs) are trophoblastic proteins belonging to the Aspartic proteinase family secreted by different placental cells of many mammalian species. They play a pivotal role in placentogenesis, foetomaternal unit remodeling, and implantation. The identification of the genes encoding those proteins will be helpful to unravel the intricate embryogenomic functions during pregnancy establishment. Considering importance of these proteins, the present study was undertaken to characterize the pregnancy associated glycoprotein-1 gene of buffalo. An 1181 base pairs buffalo Pregnancy-Associated Glycoprotein PAG-1 gene was PCR amplified from the RNA obtained from the fetal cotyledons. BLAST analysis of the buffalo PAG-1 sequence retrieved a total of 20 cattle, 5 goat, and 4 sheep PAG sequences, exhibiting more than 80% similarity. Buffalo PAG-1 gene contained an uninterrupted open reading frame of 1140 base pairs encoding 380 amino acids that possess a 15 amino acid signal peptide and mature peptide of 365 amino acids. The phylogenetic study of the buffalo PAG-1 gene revealed buffalo PAG-1 is more related to cattle, goat, and sheep PAG-1 sequences. By this study characterization of buffalo PAG-1 gene and its evolutionary relationship was deduced for the first time

A study on measuring service quality of Domino’s in Panvel Region

The purpose of this study is to measure service quality of Domino’s in Panvel Region. Dominos is one of the oldest & finest fast food restaurants since the 1960s. Dominos pizza is most preferred by the customers. The retail franchise outlet of dominos, on the Forbes Private 500 list, Domino's has the position of the 200th largest private firm. In addition to specialty items like flavored crust pizzas, Domino's offers a wide range of ‘pizza products, including pan, thin-crust and deep-dish pizzas’. Here the primary & Secondary method is used for data collection for the research. A Structured Questionnaire was prepared to collect data from the respondents for the analysis. It is observed that Paired Sample T-test ( Perceived & Expected Mean )  and Reliability Analysis is used for scale data. Resulting into P-value  0.971 which indicates that scale data is quite reliable and reductant. factors like “Reliability, Price & Usage, Assurance, Ambience, Empathy” etc are used to measure service quality of Domino’s in Panvel Region. It is concluded that variables like  Convenient staff, order & Management systems, location, cleanliness proves no significant difference between expected and perceived mean of service quality of Dominos in Panvel Region

Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti

Bianchi type-I cosmological model in Lyra\u27s manifold is obtained assuming a massless scalar field as the source of gravitational field. Some physical and geometrical properties of the model are discussed.Razvili smo Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti kada je izvor gravitacijskog polja bezmaseno skalarno polje. Raspravljaju se neka fizička i geometrijska svojstva modela

Spectrum of vulvar lesions: patient’s anxiety, clinician’s concern and pathologist’s diagnostic challenge

Background: A wide variety of inflammatory, premalignant and malignant lesions can occur on the vulva. Some of the lesions are limited to the vulva, while some also involve other parts of the body. Although vulvar diseases can cause a significant issue in the patients, they are less commonly discussed than those of cervix, uterus and ovary. Most of the asymptomatic lesions remain un-noticed, and are seen during routine gynecological checkups. Common complaints in symptomatic lesions are lumps, discomfort, itching and pain. Since the symptoms are nonspecific; determining the location of the lesion can assist with the diagnosis. Being a genital part with skin covering on outer aspect and mucosal lining inside, it is associated with various dermatological, nutritional, and hormonal as well as sexually transmitted diseases. The present study thus was conducted to categorize vulvar lesions based on their histological diagnosis and also to study the morphological spectrum of precursor lesions for malignancy.Methods: Present study includes all types of vulvar lesions sent for pathological study in the Department of pathology, at GMC Nagpur over the period of one year.Results: Total 34 lesions were studied including a wide diagnostic range from inflammatory, dermatological to benign, premalignant and malignant. Inflammatory lesions including various infections and LSA (Lichen sclerosus atrophicus) were the most commonly seen lesions along with collection of neoplastic lesions.Conclusions: Proper diagnostic categorization of the lesions is essential for initiating therapy and reducing patient’s anxiety. Morphology of these lesions along with their diagnostic significance is discussed

Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti

Bianchi type-I cosmological model in Lyra\u27s manifold is obtained assuming a massless scalar field as the source of gravitational field. Some physical and geometrical properties of the model are discussed.Razvili smo Bianchijev kozmološki model tipa I u Lyrinoj mnogostrukosti kada je izvor gravitacijskog polja bezmaseno skalarno polje. Raspravljaju se neka fizička i geometrijska svojstva modela

Neutrino mass hierarchy and octant determination with atmospheric neutrinos

The recent discovery by the Daya-Bay and RENO experiments, that \theta_{13} is nonzero and relatively large, significantly impacts existing experiments and the planning of future facilities. In many scenarios, the nonzero value of \theta_{13} implies that \theta_{23} is likely to be different from \pi/4. Additionally, large detectors will be sensitive to matter effects on the oscillations of atmospheric neutrinos, making it possible to determine the neutrino mass hierarchy and the octant of \theta_{23}. We show that a 50 kT magnetized liquid argon neutrino detector can ascertain the mass hierarchy with a significance larger than 4 sigma with moderate exposure times, and the octant at the level of 2-3 sigma with greater exposure.Comment: 4 pages, 4 figures. Version published in Phys. Rev. Let

First record of Trachicephalus uranoscopus (Bloch and Schneider, 1801) from Chilika lagoon, Odisha coast of India

1335-1337The present study deals with the first record of Trachicephalus uranoscopus and its morphological descriptions from Chilika lagoon, Odisha coast of India. The species (T. uranoscopus) as well as the family (Synanceiidae) are new additions to the ichthyofaunal diversity of the lagoon