Relief and geology of the north polar region of the planet Venus

Description of topographic features is given for the North polar region of the planet Venus. Principal geomorphic types of terrain are characterized as well as their geologic relations. Relative ages of geologic units in Venus North polar region are discussed

Радиочастотная нейроабляция в борьбе с болевым синдромом крестцово-подвздошного сустава

Синдром (дисфункция) крестцово-подвздошного сустава (КПС) является основным источником боли пояснично-крестцового отдела позвоночника у 10–25 % пациентов. Радиочастотная нейроабляция КПС была предложена в качестве продолжительного по эффективности варианта лечения болевого синдрома при непродолжительном облегчении симптомов после применения внутрисуставных инъекций гормональных препаратов. Цель исследования: анализ эффективности применения радиочастотной нейроабляции крестцово-подвздошных суставов. Материал и методы. Проанализированы данные 8 пациентов (1 мужчина и 7 женщин) в возрасте от 55 до 91 года, прошедших амбулаторное лечение в отделении реабилитации ГУ «Институт травматологии и ортопедии НАМН Украины». Результаты. Было установлено снижение болевого синдрома по ВАШ с 7,0 ± 0,41 на момент обращения до 4,33 ± 0,58, 3,75 ± 0,25 и 2,75 ± 0,33 после процедуры, через 6 и 12 мес., соответственно. Данные оценки качества жизни по анкетированию Оswestry Disability Index (ODI) и Роланда – Морриса на всех этапах наблюдения коррелируют с данными болевого синдрома по ВАШ (при начальном обследовании rcan = 0,74, на момент окончательного наблюдения rcan = 0,99). Выводы: Радиочастотная нейроабляция – эффективный метод лечения болевого синдрома крестцово- подвздошного сустава

Effect of antibodies to glutamate on age-related memory changes in C57Bl/6 mice

Chronic intranasal administration of antibodies to glutamate to aging C57Bl/6 mice improved passive avoidance conditioning, had no effect on horizontal and vertical locomotor activity, but slowed locomotion in the open-field test. Administration of antibodies to glutamate increased the content of dopamine and its metabolites in mouse hippocampus, but had no effect on the metabolism of neurotransmitter amino acids. In the frontal cortex, antibodies to glutamate did not affect neurotransmitter metabolism, but increased the level of both excitatory and inhibitory amino acids without changing their ratio

The alimentary impact of the hemp seed

Hemp seed and hemp seed oil can supply us with many important substances. Their essential fatty acid compositions are favourable, but they may contain non-psychotropic cannabinoids. Emerging data show that these components can influence the health status of the population beneficially. Some data also showed trace amounts of tetrahydrocannabinol in seed oils, the main psychotropic cannabinoid that is contraindicated.Our aim was to examine cannabinoids and fatty acid composition as well as metal and non-metal element compositions in products, like hemp seed oil and chopped hemp seed capsule.The cannabinoids were separated by thin layer chromatography. Fatty acid composition was determined with gas chromatography, and elements (Al, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, P, Pb, S, Si, Sn, Sr, V, and Zn) were measured by inductively coupled plasma optical emission spectrometric method. Selenium was determined with polarographic analyser.Cannabinoids were not detectable by thin layer chromatography, so hemp seed oil, as well as the capsule, have no psychotropic adverse effect. Our data showed that hemp seed contains essential fatty acids close to the recommended ratio. The B and Se concentrations of the oils and the P concentration of the capsule are also relevant

Delayed behavioral and neurochemical effects of anti-glutamate antibodies in aging C57BL/6 mice

We analyzed delayed effect of intranasal administration of anti-glutamate antibodies on mnestic function and tissue concentrations of neurotransmitters in the hippocampus and prefrontal cortex in aging C57BL/6 mice. It was found that after 14-day administration of anti-glutamate antibodies, improvement of the passive avoidance conditioning persisted for 7 days after the treatment was discontinued. In 7 days after discontinuation of treatment, increased content of dopamine and its metabolites as well as aspartic acid and taurine was observed in the hippocampus of mice treated with anti-glutamate antibodies. In the prefrontal cortex, administration of anti-glutamate antibodies had no effect on the levels of neurotransmitters, but increased the concentration of glutamate