1,750 research outputs found
A Study to Determine Where and at What Age Senior Boys in Three Selected Senior High Schools of Utah Acquired Knowledge and Skill in Activities
The purpose of this study is to determine the student\u27s ability (according to his own rating), where his interests lie, and at what age, and where male students first learned physical activities that are taught in the high schools of Utah
Probing neutrino and Higgs sectors in model with lepton-flavor non-universality
The neutrino and Higgs sectors in the \mbox{SU(2)}_1 \times \mbox{SU(2)}_2
\times \mbox{U(1)}_Y model with lepton-flavor non-universality are discussed.
We show that active neutrinos can get Majorana masses from radiative
corrections, after adding only new singly charged Higgs bosons. The mechanism
for generation of neutrino masses is the same as in the Zee models. This also
gives a hint to solving the dark matter problem based on similar ways discussed
recently in many radiative neutrino mass models with dark matter. Except the
active neutrinos, the appearance of singly charged Higgs bosons and dark matter
does not affect significantly the physical spectrum of all particles in the
original model. We indicate this point by investigating the Higgs sector in
both cases before and after singly charged scalars are added into it. Many
interesting properties of physical Higgs bosons, which were not shown
previously, are explored. In particular, the mass matrices of charged and
CP-odd Higgs fields are proportional to the coefficient of triple Higgs
coupling . The mass eigenstates and eigenvalues in the CP-even Higgs
sector are also presented. All couplings of the SM-like Higgs boson to normal
fermions and gauge bosons are different from the SM predictions by a factor
, which must satisfy the recent global fit of experimental data, namely
. We have analyzed a more general diagonalization of gauge boson
mass matrices, then we show that the ratio of the tangents of the and
mixing angles is exactly the cosine of the Weinberg angle, implying that
number of parameters is reduced by 1. Signals of new physics from decays of new
heavy fermions and Higgs bosons at LHC and constraints of their masses are also
discussed.Comment: 40 pages, 1 figure; Journal vesio
General one-loop formulas for decay
Radiative corrections to the are evaluated in the
one-loop approximation. The unitary gauge gauge is used. The analytic result is
expressed in terms of the Passarino-Veltman functions. The calculations are
applicable for the Standard Model as well for a wide class of its gauge
extensions. In particular, the decay width of a charged Higgs boson can be derived. The consistence of our formulas and
several specific earlier results is shown.Comment: 33 pages, 3 figures, a new section (V) and references were improved
in the published versio
Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation
BACKGROUND: The hematopoietic syndrome of the acute radiation syndrome (HSARS) is a life-threatening condition in humans exposed to total body irradiation (TBI); no drugs are approved for treating this condition. Recombinant human interleukin-12 (rHuIL-12) is being developed for HSARS mitigation under the FDA Animal Rule, where efficacy is proven in an appropriate animal model and safety is demonstrated in humans. METHODS: In this blinded study, rhesus monkeys (9 animals/sex/dose group) were randomized to receive a single subcutaneous injection of placebo (group 1) or rHuIL-12 at doses of 50, 100, 250, or 500 ng/kg (groups 2–5, respectively), without antibiotics, fluids or blood transfusions, 24–25 hours after TBI (700 cGy). RESULTS: Survival rates at Day 60 were 11%, 33%, 39%, 39%, and 50% for groups 1–5, respectively (log rank p < 0.05 for each dose vs. control). rHuIL-12 also significantly reduced the incidences of severe neutropenia, severe thrombocytopenia, and sepsis (positive hemoculture). Additionally, bone marrow regeneration following TBI was significantly greater in monkeys treated with rHuIL-12 than in controls. CONCLUSIONS: Data from this study demonstrate that a single injection of rHuIL-12 delivered one day after TBI can significantly increase survival and reduce radiation-induced hematopoietic toxicity and infections. These data significantly advance development of rHuIL-12 toward approval under the Animal Rule as an effective stand-alone medical countermeasure against the lethal effects of radiation exposure
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