199 research outputs found

    Asymmetric multilayers elements for magnetic detection

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    In this paper, we study a magnetic impedance characteristics of film multilayer elements of the strip type [Ti / FeNi] 5 / Ti / Cu / Ti / (FeNi / Ti) x, x = 0...5, prepared by magnetron sputtering. We observed in these structures similar type of magnetization reversal in an array of layers between the substrate and the central conductive layer of copper for all the samples and changing the type of magnetization reversal in the array of the conductive layer of copper with a decrease in the number of upper magnetic layers. Despite the fact that the absolute maximum MI ratio amounted impedance ΔZ / Z = 126% for a symmetrical structure, an asymmetrical structure with four magnetic layers above the layer of copper also has high MI ratio ΔZ / Z = 121% in the lower fields, which allows to recommend asymmetric structure for the subsequent functionalization of the upper layer in detectors of weak magnetic fields.В данной работе исследуются особенности магнитного импеданса плёночных многослойных элементов в форме полос типа [Ti/FeNi]5/Ti/Cu/Ti/(FeNi/Ti)x, x = 0…5, полученных магнетронным распылением. На полученных структурах наблюдался сходный тип перемагничивания в массиве слоев между подложкой и центральным проводящим слоем меди для всех образцов и смена типа перемагничивания в массиве над проводящим слоем меди при уменьшении количества верхних магнитных слоев. Несмотря на то, что абсолютный максимум МИ соотношения импеданса составил ∆Z/Z=126% для симметричной структуры, асимметричная структура с 4 магнитными слоями над слоем меди также обладает высоким МИ соотношением ∆Z/Z=121% в меньших полях, что позволяет рекомендовать асимметричную структуру для последующей функционализации верхнего слоя в детекторах слабых магнитных полей

    Design magnetic matrices for cell technology supporting devices

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    Biomedical applications of magnetic materials are a hot topic of present day research. Special attention is paid for design and development of appropriate instrumentation. In this work magnetic system consisting of an equidistant set of commercial permanent magnets (6 × 4 assay) was proposed, designed and tested for further employment in the experiments in cell cultivation experiments. Magnetic field distribution was experimentally measured in 3 axes: OX, OY, OZ by gaussmeter. The results were statistically analyzed. Constant magnetic field near the center of XY plane was relatively homogeneous but at edges significant value of magnetic field gradient was observed. With increasing of Z distance, the decreasing of magnetic field strength was observed. Obtained parameters of a designed system are satisfactory and therefore it can be recommended for cell cultivation experiments when application of external magnetic field is desired. © Published under licence by IOP Publishing Ltd.Russian Science Foundation, RSF: 18-19-00090This research was funded by the Russian Science Foundation, grant number 18-19-00090

    Broadband Microwave Absorption in Co-Based Amorphous Ribbons

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    Ferromagnetic resonance of Fe3Co67Cr3Si15B12 amorphous ribbons was measured using Rohde&Schwartz ZVA-67 Vector Network Analyzer in a wide frequency range 1–15 GHz.This research was funded by Ministry of Science and Higher Education of the Russian Federation, grant number FEUZ-2020-0051

    Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization

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    The protein C is a small viral protein encoded in an overlapping frame of the P gene in the subfamily Orthoparamyxovirinae. This protein, expressed by alternative translation initiation, is a virulence factor that regulates viral transcription, replication, and production of defective interfering RNA, interferes with the host-cell innate immunity systems and supports the assembly of viral particles and budding. We expressed and purified full-length and an N-terminally truncated C protein from Tupaia paramyxovirus (TupV) C protein (genus Narmovirus). We solved the crystal structure of the C-terminal part of TupV C protein at a resolution of 2.4 Å and found that it is structurally similar to Sendai virus C protein, suggesting that despite undetectable sequence conservation, these proteins are homologous. We characterized both truncated and full-length proteins by SEC-MALLS and SEC-SAXS and described their solution structures by ensemble models. We established a mini-replicon assay for the related Nipah virus (NiV) and showed that TupV C inhibited the expression of NiV minigenome in a concentration-dependent manner as efficiently as the NiV C protein. A previous study found that the Orthoparamyxovirinae C proteins form two clusters without detectable sequence similarity, raising the question of whether they were homologous or instead had originated independently. Since TupV C and SeV C are representatives of these two clusters, our discovery that they have a similar structure indicates that all Orthoparamyxovirine C proteins are homologous. Our results also imply that, strikingly, a STAT1-binding site is encoded by exactly the same RNA region of the P/C gene across Paramyxovirinae, but in different reading frames (P or C), depending on which cluster they belong to.French Agence Nationale de la RechercheFond de la Recherche Médicale (FRM)Grenoble Instruct-ERIC centerFRISBIUniversity Grenoble Alpes graduate school (Ecoles Universitaires de Recherche)Peer Reviewe

    Computer modeling methods for solving the tasks of interventional cardiology

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    This work is devoted to the development of technology for computer visualization of cardiac vessels and assessment of the morphofunctional characteristics of the coronary arteries based on the results of standard angiographic examination of patients. Automated computer modeling methods based on the finite element method are considered.Настоящая работа посвящена разработке технологии для компьютерной визуализации сосудов сердца и оценки морфофункциональных характеристик коронарных артерий по результатам стандартного ангиографического обследования пациентов. Рассмотрены автоматизированные методы компьютерного моделирования на основе метода конечных элементов

    Computer modeling methods for solving the tasks of interventional cardiology

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    This work is devoted to the development of technology for computer visualization of cardiac vessels and assessment of the morphofunctional characteristics of the coronary arteries based on the results of standard angiographic examination of patients. Automated computer modeling methods based on the finite element method are considered.Настоящая работа посвящена разработке технологии для компьютерной визуализации сосудов сердца и оценки морфофункциональных характеристик коронарных артерий по результатам стандартного ангиографического обследования пациентов. Рассмотрены автоматизированные методы компьютерного моделирования на основе метода конечных элементов
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