Performance Analysis of Water Filtration Units for Reduction of pH, Turbidity, Solids and Electricity Conductivity

The main objective of this study was to analyze the performance of different filtration units that reduce turbidity, pH, total dissolved solids (TDS) and electrical conductivity (EC) of canal water. For that, three different types of filtration units, namely, slow sand, rapid sand and dual media were fabricated. Typical parameters of canal and filtered water, like pH, turbidity, TDS and EC were examined, and then the filtered water quality was compared with World Health Organizations (WHO) standards. Maximum pH reduction was noted with dual media and less by the rapid system, while more turbidity was reduced with the slow sand and less with the dual media filtration system. In contrary to the pH and turbidity results, increment in both TDS and EC values were noted in filtered samples compared to that of raw water samples due to the transfer of dissolved minerals present in the sand into the filtered water during the contact period with media in the bed. However, all examined parameters of filtered water were within WHO standards

Evaluating implementation of LEAPS, a youth-led early childhood care and education intervention in rural Pakistan: protocol for a stepped wedge cluster-randomized trial

BACKGROUND: The Sustainable Development Goals (SDGs) highlight the importance of investments in early childhood care and education (ECCE) and youth development. Given Pakistan's large young population, and gender and urban-rural inequalities in access to education, training, and employment, such investments offer opportunities. LEAPS is a youth-led ECCE program that trains female youth, 18-24 years, as Community Youth Leaders (CYLs) to deliver high-quality ECCE for children, 3.5-5.5 years, in rural Sindh, Pakistan. METHODS: We use a stepped wedge cluster-randomized trial to evaluate implementation of LEAPS. Ninety-nine clusters will be randomized to receive the intervention in one of three 7-month steps (33 clusters/step). The primary outcome is children's school readiness (indexed by the total score on the International Development and Early Learning Assessment (IDELA)). Secondary child outcomes are children's IDELA domain scores and executive functions. Data are collected in cross-sectional surveys of 1089 children (11 children/cluster from 99 clusters) aged 4.5-5.5 years at four timepoints (baseline and at the end of each step). Additionally, we will enroll three non-randomized youth participant open cohorts, one per step (33 CYLs: 66 comparison youth per cohort; 99:198 in total). Youth cohorts will be assessed at enrollment and every 7 months thereafter to measure secondary outcomes of youth personal and professional development, depressive symptoms, and executive functions. A non-randomized school cohort of 330 LEAPS students (10 students/cluster from 33 clusters) will also be enrolled and assessed during Step 1 after intervention rollout and at endline. The quality of the learning environment will be assessed in each LEAPS ECCE center and in a comparison center at two timepoints midway following rollout and at endline. A concurrent mixed-methods implementation evaluation will assess program fidelity and quality, and the extent to which a technical support strategy is successful in strengthening systems for program expansion. A cost evaluation will assess cost per beneficiary. Data collection for implementation and cost evaluations will occur in Step 3. DISCUSSION: Youth-led models for ECCE offer a promising approach to support young children and youth. This study will contribute to the evidence as a means to promote sustainable human development across multiple SDG targets. TRIAL REGISTRATION: ClinicalTrials.gov NCT03764436 . Registered on December 5, 2018

RECLAMATION OF SALINE CLAY SOIL WITH DIFFERENT LEACHING METHOD

The availability of water for land reclamation is limited due to water shortage crises in the world. An experiment of leaching of saline soil in micro-plots of size 3m x 4 m was carried out with different leaching methods in order to assess their leaching efficiency. Three leaching methods viz. continuous ponding, continuous ponding With 5 cm salt crust removal (scrapping) and continuous ponding with tillage were used. Equal depth of water (70cm) was applied to all the plots replicated three times for 30 days. Soil samples were taken regularly from all plots at soil depths of 0, 20, 30, 40, 60 and 80 cm for determining the change in EC of the soil. The experimental results revealed that continuous ponding with tillage was efficient method of leaching than other leaching methods used in this experiment. The continuous ponding with tillage method of leaching was efficient because small aggregates were formed and the salts held in small aggregates diffused faster due to shorter diffusion pathways

Applications of nanotechnology in diagnostics and therapeutics of Alzheimer's and Parkinson's disease

In this paper, an extended review analysis has been presented concerning the developments in brain drug delivery through new and efficient applications of nanotechnology. Modern nanotechnological approaches for the diagnosis and treatment of Alzheimer's and Parkinson's diseases are described along with simultaneous analysis of safety and practical clinical usage of these strategies. © 2015 Bentham Science Publishers

Groundwater Quality Analysis for Human Consumption: A Case Study of Sukkur City, Pakistan

Drinking water quantity and quality is of the utmost importance. If the drinking water gets contaminated, it can result in severe health problems. For example, the continuous consumption of drinking water containing more than permissible amounts of fluoride can lead to bone deterioration and increased risk of bone fracture [1]. The present study was carried out to check the quality of underground water of Sukkur city. The analyzed parameters were fluoride, sodium, magnesium, calcium, potassium, iron, arsenic, TDS, pH, conductivity, odor, color and taste. World Health Organization (WHO) standards were followed in present study. Underground water samples were collected from 20 different populated locations of Sukkur city. Only arsenic, pH, iron and potassium were found to be within health safe limits while the rest of the parameters exceeded the permissible standards set out by WHO. The TDS, sodium, fluoride and magnesium were over the limits at some locations