Application of Evaporation Method Using Two Tensiometers for Determining Unsaturated Hydraulic Conductivity beyond Tensiometric Range

Accurate determination of unsaturated hydraulic conductivity in low pressure head range is critical for predicting evaporation rate under localized irrigation or root water uptake under drought stress conditions. We proposed a relatively low cost and fast laboratory method to simultaneously determine water retention and hydraulic conductivity functions across a wide range of pressure heads. The method is quite similar to conventional evaporation method using two tensiometers. In addition to tensiometer readings, the proposed method uses water content profile at the end and cumulative evaporation. Experimental results for three soils with different textures showed that inversely optimized hydraulic conductivity functions agreed with K-data measured with the steady state evaporation method, indicating the reliability of the proposed method. The hydraulic conductivity functions fitted for K-data obtained by tensiometer readings with Campbell’s K(θ) function also agreed well with the reference K-data for two of the three soils, but largely deviated from those for the third soil. This indicates the importance of actual measurement of K(θ) in low pressure head range

Direct observation of the current oscillation in a dc SQUID

学術論文 (Article)journal articl

NMR and NQR study of pressure-induced superconductivity and the origin of critical-temperature enhancement in the spin-ladder cuprate Sr2_2Ca12_{12}Cu24_{24}O41_{41}

Pressure-induced superconductivity was studied for a spin-ladder cuprate Sr$_2$Ca$_{12}$Cu$_{24}$O$_{41}$ using nuclear magnetic resonance (NMR) under pressures up to the optimal pressure 3.8 GPa. Pressure application leads to a transitional change from a spin-gapped state to a Fermi-liquid state at temperatures higher than $T_c$. The relaxation rate $1/T_1$ shows activated-type behavior at an onset pressure, whereas Korringa-like behavior becomes predominant at the optimal pressure, suggesting that an increase in the density of states (DOS) at the Fermi energy leads to enhancement of $T_c$. Nuclear quadrupole resonance (NQR) spectra suggest that pressure application causes transfer of holes from the chain to the ladder sites. The transfer of holes increases DOS below the optimal pressure. A dome-shaped $T_c$ versus pressure curve arises from naive balance between the transfer of holes and broadening of the band width

The degree of aqueous alteration of nine CM chondrites estimated from mineralogy and chemical variations of matrix.

第2回極域科学シンポジウム/第34回南極隕石シンポジウム 11月17日（木） 国立国語研究所 2階講

Huntingtin-lowering strategies for Huntington's disease.

INTRODUCTION: Huntington's disease (HD) is an incurable, autosomal dominant neurodegenerative disease caused by an abnormally long polyglutamine tract in the huntingtin protein. Because this mutation causes disease via gain-of-function, lowering huntingtin levels represents a rational therapeutic strategy. AREAS COVERED: We searched MEDLINE, CENTRAL, and other trial databases, and relevant company and HD funding websites for press releases until April 2020 to review strategies for huntingtin lowering, including autophagy and PROTACs, which have been studied in preclinical models. We focussed our analyses on oligonucleotide (ASOs) and miRNA approaches, which have entered or are about to enter clinical trials. EXPERT OPINION: ASO and mRNA approaches for lowering mutant huntingtin protein production and strategies for increasing mutant huntingtin clearance are attractive because they target the cause of disease. However, questions concerning the optimal mode of delivery and associated safety issues remain. It is unclear if the human CNS coverage with intrathecal or intraparenchymal delivery will be sufficient for efficacy. The extent that one must lower mutant huntingtin levels for it to be therapeutic is uncertain and the extent to which CNS lowering of wild-type huntingtin is safe is unclear. Polypharmacy may be an effective approach for ameliorating signs and symptoms and for preventing/delaying onset and progression

A quantitative model for IcR product in d-wave Josephson junctions

We study theoretically the Josephson effect in d-wave superconductor / diffusive normal metal /insulator/ diffusive normal metal/ d-wave superconductor (D/DN/I/DN/D) junctions. This model is aimed to describe practical junctions in high-$T_C$ cuprate superconductors, in which the product of the critical Josephson current ($I_C$) and the normal state resistance ($R$) (the so-called $I_{\rm C}R$ product) is very small compared to the prediction of the standard theory. We show that the $I_{\rm C}R$ product in D/DN/I/DN/D junctions can be much smaller than that in d-wave superconductor / insulator / d-wave superconductor junctions and formulate the conditions necessary to achieve large $I_{\rm C}R$ product in D/DN/I/DN/D junctions. The proposed theory describes the behavior of $I_{\rm C}R$ products quantitatively in high-$T_{\rm C}$ cuprate junctions.Comment: 4 pages, 6 figure

Experimental observation of the crystallization of a paired holon state

A new excitation is observed at 201 meV in the doped-hole ladder cuprate Sr$_{14}$Cu$_{24}$O$_{41}$, using ultraviolet resonance Raman scattering with incident light at 3.7 eV polarized along the direction of the rungs. The excitation is found to be of charge nature, with a temperature independent excitation energy, and can be understood via an intra-ladder pair-breaking process. The intensity tracks closely the order parameter of the charge density wave in the ladder (CDW$_L$), but persists above the CDW$_L$ transition temperature ($T_{CDW_L}$), indicating a strong local pairing above $T_{CDW_L}$. The 201 meV excitation vanishes in La$_{6}$Ca$_{8}$Cu$_{24}$O$_{41+\delta}$, and La$_{5}$Ca$_{9}$Cu$_{24}$O$_{41}$ which are samples with no holes in the ladders. Our results suggest that the doped holes in the ladder are composite bosons consisting of paired holons that order below $T_{CDW}$.Comment: Accepted for publication in Physical Review Letters (4 figures