Genomic structure of the bovine <i>ALX4</i> gene and positions of variants detected in Galloway cattle.

<p>The genomic structure of the bovine <i>ALX4</i> gene as deduced from AC_00172 (Bos_taurus_UMD_3.1), NC_007313 (Btau_4.6.1), and NM_001030304 is depicted [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0129208#pone.0129208.ref033" target="_blank">33</a>]. Sizes of intron 1 and 2 are not yet known due to larger gaps. Numbering of positions refers to AC_000172. Duplicated sequences in exon 2 and exon 4 in the affected animals are shown with gray bars. Numbers below the sequences indicate the corresponding nucleotide positions of the wildtype (wt_ex2, wt_ex4) and mutated (mut_ex2dup, mut_ex4dup) alleles within the corresponding exon. Positions of the SNPs and duplications according to HGVS [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0129208#pone.0129208.ref035" target="_blank">35</a>] are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0129208#pone.0129208.t002" target="_blank">Table 2</a>.</p