53 research outputs found

    Controlled Release of Drugs fromMicroparticles Produced by Ultrasonic Assisted Atomization Based on Biocompatible Polymers

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    Microencapsulation of active molecules in biocompatible polymers is a matter of great interest in pharmaceutical sciences. Ultrasonic assisted atomization as a new technique to produce microencapsulated systems seems to offer several advantages (low level of mechanical stress in materials, reduced energy request, reduced apparatuses size) with respect to more conventional techniques. In this work, fine drug-loaded particles were produced by ionic reticulation of droplets obtained by ultrasonic atomization of biopolymers solutions. The particles were then characterized in terms of morphology and drug release kinetics. Data were used to estimate the PNMS (Polymeric Network Mesh-Size) with the aims of clarifying its role in controlled drug release, and analyzing its relationships with material and process parameters. For materials and operative conditions investigated, the calculated PNMS was found consistent with a fast release of drugs of small molecular size

    Controlled Release of Drugs fromMicroparticles Produced by Ultrasonic Assisted Atomization Based on Biocompatible Polymers

    Get PDF
    Microencapsulation of active molecules in biocompatible polymers is a matter of great interest in pharmaceutical sciences. Ultrasonic assisted atomization as a new technique to produce microencapsulated systems seems to offer several advantages (low level of mechanical stress in materials, reduced energy request, reduced apparatuses size) with respect to more conventional techniques. In this work, fine drug-loaded particles were produced by ionic reticulation of droplets obtained by ultrasonic atomization of biopolymers solutions. The particles were then characterized in terms of morphology and drug release kinetics. Data were used to estimate the PNMS (Polymeric Network Mesh-Size) with the aims of clarifying its role in controlled drug release, and analyzing its relationships with material and process parameters. For materials and operative conditions investigated, the calculated PNMS was found consistent with a fast release of drugs of small molecular size

    A Comunicação da Responsabilidade Social Empresarial (RSE) na Suécia, Tailândia e Brasil: uma abordagem comparativa em empresas de construção civil

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    A Responsabilidade Social Empresarial (RSE) tem recebido crescente atenção, tanto na área acadêmica como corporativa. As empresas, geralmente, definem sua abordagem de RSE sob diferentes visões, sendo influenciadas por distintos fatores em nível regional, industrial, nacional e empresarial. O presente estudo tem como objetivo identificar como as maiores empresas da indústria de construção civil da Suécia, Tailândia e Brasil se apresentam em termos de Responsabilidade Social Empresarial. A pesquisa foi realizada mediante a análise de documentos organizacionais provenientes das maiores empresas de construção civil dos países mencionados. Para coleta de dados, utilizou-se o modelo proposto por Silberhorn e Warren (2007) que inclui princípios motivadores da RSE, processos de RSE e questões relacionadas a Stakeholders. Os resultados sugerem que as motivações corporativas para a RSE são direcionadas predominantemente por valores, o que indica que a RSE tem se tornado um tema estratégico inserido nos valores corporativos. Observou-se uma distinção entre as empresas dos três países. As empresas suecas possuem foco na perspectiva ambiental, as tailandesas na perspectiva econômica por meio da governança corporativa e accountability, enquanto que as empresas brasileiras focam uma perspectiva social

    Micro-Systems Production: A Promising New Technique with Low Energy Consumption

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    Nowadays, a considerable range of industrial applications (pharmaceutics, cosmetics, foods agriculture products) relies on microencapsulation of solids or liquids by polymer coating and entrapment into polymer matrices. [...
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