1,638 research outputs found
Detecting Spin-Polarized Currents in Ballistic Nanostructures
We demonstrate a mesoscopic spin polarizer/analyzer system that allows the
spin polarization of current from a quantum point contact in an in-plane
magnetic field to be measured. A transverse focusing geometry is used to couple
current from an emitter point contact into a collector point contact. At large
in-plane fields, with the point contacts biased to transmit only a single spin
(g < e^2/h), the voltage across the collector depends on the spin polarization
of the current incident on it. Spin polarizations of greater than 80% are found
for both emitter and collector at 300mK and 7T in-plane field.Comment: related papers at http://marcuslab.harvard.ed
The Open Access Advantage Revisited
This paper is a revision of one that appeared in 2008, incorporating the many developments and changes that have happened since then.published_or_final_versio
Mechanical suppression of osteolytic bone metastases in advanced breast cancer patients: A randomised controlled study protocol evaluating safety, feasibility and preliminary efficacy of exercise as a targeted medicine
Background: Skeletal metastases present a major challenge for clinicians, representing an advanced and typically incurable stage of cancer. Bone is also the most common location for metastatic breast carcinoma, with skeletal lesions identified in over 80% of patients with advanced breast cancer. Preclinical models have demonstrated the ability of mechanical stimulation to suppress tumour formation and promote skeletal preservation at bone sites with osteolytic lesions, generating modulatory interference of tumour-driven bone remodelling. Preclinical studies have also demonstrated anti-cancer effects through exercise by minimising tumour hypoxia, normalising tumour vasculature and increasing tumoural blood perfusion. This study proposes to explore the promising role of targeted exercise to suppress tumour growth while concomitantly delivering broader health benefits in patients with advanced breast cancer with osteolytic bone metastases.
Methods: This single-blinded, two-armed, randomised and controlled pilot study aims to establish the safety, feasibility and efficacy of an individually tailored, modular multi-modal exercise programme incorporating spinal isometric training (targeted muscle contraction) in 40 women with advanced breast cancer and stable osteolytic spinal metastases. Participants will be randomly assigned to exercise or usual medical care. The intervention arm will receive a 3-month clinically supervised exercise programme, which if proven to be safe and efficacious will be offered to the control-arm patients following study completion. Primary endpoints (programme feasibility, safety, tolerance and adherence) and secondary endpoints (tumour morphology, serum tumour biomarkers, bone metabolism, inflammation, anthropometry, body composition, bone pain, physical function and patient-reported outcomes) will be measured at baseline and following the intervention.
Discussion: Exercise medicine may positively alter tumour biology through numerous mechanical and nonmechanical mechanisms. This randomised controlled pilot trial will explore the preliminary effects of targeted exercise on tumour morphology and circulating metastatic tumour biomarkers using an osteolytic skeletal metastases model in patients with breast cancer. The study is principally aimed at establishing feasibility and safety. If proven to be safe and feasible, results from this study could have important implications for the delivery of this exercise programme to patients with advanced cancer and sclerotic skeletal metastases or with skeletal lesions present in haematological cancers (such as osteolytic lesions in multiple myeloma), for which future research is recommended.
Trial registration: anzctr.org.au, ACTRN-12616001368426. Registered on 4 October 2016
Theory of Current-Induced Magnetization Precession
We solve appropriate drift-diffusion and Landau-Lifshitz-Gilbert equations to
demonstrate that unpolarized current flow from a non-magnet into a ferromagnet
can produce a precession-type instability of the magnetization. The fundamental
origin of the instability is the difference in conductivity between majority
spins and minority spins in the ferromagnet. This leads to spin accumulation
and spin currents that carry angular momentum across the interface. The
component of this angular momentum perpendicular to the magnetization drives
precessional motion that is opposed by Gilbert damping. Neglecting magnetic
anisotropy and magnetostatics, our approximate analytic and exact numerical
solutions using realistic values for the material parameters show (for both
semi-infinite and thin film geometries) that a linear instability occurs when
both the current density and the excitation wave vector parallel to the
interface are neither too small nor too large. For many aspects of the problem,
the variation of the magnetization in the direction of the current flows makes
an important contribution.Comment: Submitted to Physical Review
Spin separation in cyclotron motion
Charged carriers with different spin states are spatially separated in a
two-dimensional hole gas. Due to strong spin-orbit interaction holes at the
Fermi energy have different momenta for two possible spin states travelling in
the same direction and, correspondingly, different cyclotron orbits in a weak
magnetic field. Two point contacts, acting as a monochromatic source of
ballistic holes and a narrow detector in the magnetic focusing geometry are
demonstrated to work as a tunable spin filter.Comment: 4 pages, 2 figure
Growth conditions, structure, and superconductivity of pure and metal-doped FeTe1-xSex single crystals
Superconducting single crystals of pure FeTe1 xSex and FeTe0.65Se0.35 doped
with Co, Ni, Cu, Mn, Zn, Mo, Cd, In, Pb, Hg, V, Ga, Mg, Al, Ti, Cr, Sr or Nd
into Fe ions site have been grown applying Bridgman's method. It has been found
that the sharpness of transition to the superconducting state in FeTe1 xSex is
evidently inversely correlated with crystallographic quality of the crystals.
Among all of the studied dopants only Co, Ni and Cu substitute Fe ions in
FeTe0.65Se0.35 crystals. The remaining examined ions do not incorporate into
the crystal structure. Nevertheless, they form inclusions together with
selenium, tellurium and/or iron, what changes the chemical composition of host
matrix and therefore influences Tc value. Small disorder introduced into
magnetic sublattice, by partial replacement of Fe ions by slight amount of
nonmagnetic ions of Cu (~ 1.5 at%) or by magnetic ions of Ni (~ 2 at%) and Co
(~5 at%) with spin value different than that of Fe ion, completely suppresses
superconductivity in FeTe1 xSex system. This indicates that even if
superconductivity is observed in the system containing magnetic ions it can not
survive when the disorder in magnetic ions sublattice is introduced, most
likely because of magnetic scattering of Cooper pairs.Comment: 18 pages, 12 figures, 3 table
Microwave Oscillations of a Nanomagnet Driven by a Spin-Polarized Current
We describe direct electrical measurements of microwave-frequency dynamics in
individual nanomagnets that are driven by spin transfer from a DC
spin-polarized current. We map out the dynamical stability diagram as a
function of current and magnetic field, and we show that spin transfer can
produce several different types of magnetic excitations, including small-angle
precession, a more complicated large-angle motion, and a high-current state
that generates little microwave signal. The large-angle mode can produce a
significant emission of microwave energy, as large as 40 times the
Johnson-noise background.Comment: 12 pages, 3 figure
Spin Torques in Ferromagnetic/Normal Metal Structures
Recent theories of spin-current-induced magnetization reversal are formulated
in terms of a spin-mixing conductance . We evaluate from
first-principles for a number of (dis)ordered interfaces between magnetic and
non-magnetic materials. In multi-terminal devices, the magnetization direction
of a one side of a tunnel junction or a ferromagnetic insulator can ideally be
switched with negligible charge current dissipation.Comment: 4 pages, 1 figur
Cascaded two-photon nonlinearity in a one-dimensional waveguide with multiple two-level emitters
We propose and theoretically investigate a model to realize cascaded optical
nonlinearity with few atoms and photons in one-dimension (1D). The optical
nonlinearity in our system is mediated by resonant interactions of photons with
two-level emitters, such as atoms or quantum dots in a 1D photonic waveguide.
Multi-photon transmission in the waveguide is nonreciprocal when the emitters
have different transition energies. Our theory provides a clear physical
understanding of the origin of nonreciprocity in the presence of cascaded
nonlinearity. We show how various two-photon nonlinear effects including
spatial attraction and repulsion between photons, background fluorescence can
be tuned by changing the number of emitters and the coupling between emitters
(controlled by the separation).Comment: 6 pages, 4 figure
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