164 research outputs found

    Large thoracic tumour without superior vena cava syndrome

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    A 62-year-old male with long-standing smoking history presented with haemoptysis. Plain chest X-ray showed abnormal findings proximate to the right pulmonary hilum. Bronchoscopy revealed a fragile exophytic tumour of the right wall of the lower third of the trachea, infiltrating the right main bronchus (75% stenosis) and the right upper lobar bronchus (near total occlusion). Contrast-enhanced chest computed tomography demonstrated a 7.2 × 4.9 cm tumour contiguous to the above-mentioned structures, mediastinal lymph node pathology, and a vessel coursing inferiorly to the left of the aortic arch and anterior to the left hilum. Despite the tumour constricting the right superior vena cava (SVC), no signs of SVC syndrome were present. In this case, the patient does not present with SVC syndrome, as expected due to the constriction of the (right) SVC caused by the tumour, since head and neck veins drain through the persistent left superior vena cava (PLSVC). PLSVC is the most common thoracic venous anomaly with an incidence of 0.3% to 0.5% of the general population and it is a congenital anomaly caused by the failure of the left anterior cardinal vein to regress and to consequently form the ligament of Marshall during foetal development. It is associated with absence of the left brachiocephalic vein and in 10% to 20% of cases the right SVC is absent. Two potential draining points of the PLSVC have been previously reported. In the majority of cases PLSVC drains directly into the coronary sinus, but less frequently it drains into the left atrium or the left superior pulmonary vein (LSPV). In cases where the PLSVC drains into the coronary sinus, congenital heart defects are rare. The patient usually remains asymptomatic and PLSVC is an incidental finding during radiographic imaging or medical procedures. When the PLSVC drains into the left atrium or the LSPV, a right-to-left shunt is formed; a condition usually asymptomatic. In some reported cases this PLSVC variant presents with persistent, unexplained hypoxia or cyanosis and embolisation causing recurrent transient ischaemic attacks and/or cerebral abscesses. This PLSVC variant is more often associated with absence of the right SVC and congenital heart abnormalities.

    A protein-glucan intermediate during paramylon synthesis

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    “Luck’s always to blame”: silent wounds of a penetrating gunshot trauma sustained 20 years ago

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    Gunshot tracheal injuries represent life-threatening events and usually necessitate emergent surgical intervention. We report a case of an exceptional finding of a patient with retained ballistic fragments in the soft tissues of the thorax, proximal to the right subclavian artery and the trachea, carrying silently his wounds for two decades without any medical or surgical intervention. The bullet pellet on the upper part of the trachea seen accidentally in the chest computed tomography, was also found during bronchoscopy. In short “luck’s always to blame”

    Diffuse Idiopathic Skeletal Hyperostosis (DISH) and non small cell lung cancer: case presentation and review of the literature

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    Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier’s disease, is a systemic non inflammatory disease of unknown cause. It is characterized by the presence of osteophytes due to calcification and ossification of spinal ligaments and entheses. Moreover, diffuse idiopathic skeletal hyperostosis has been associated with a variety of metabolic disorders. However, to the best of our knowledge no association with non small cell lung cancer (NSCLC) has been reported so far. In the present study we report a case of a patient with NSCLC and DISH.Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier’s disease, is a systemic non inflammatory disease of unknown cause. It is characterized by the presence of osteophytes due to calcification and ossification of spinal ligaments and entheses. Moreover, diffuse idiopathic skeletal hyperostosis has been associated with a variety of metabolic disorders. However, to the best of our knowledge no association with non small cell lung cancer (NSCLC) has been reported so far. In the present study we report a case of a patient with NSCLC and DISH

    Successful combined surgical approach in a rare case of retrotracheal goitre in a patient with anatomical impediments

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    Diving goitres can descend the cervical region expanding directly into the thoracic cavity. In most cases, diving goitres extend into the anterosuperior compartment, but they may also extend behind the trachea. We herein present a case of a male patient with retrotracheal goitre and history of left thyroid lobectomy and median sternotomy for thoracic aortic aneurysm repair with graft placement. After detailed preoperative evaluation, the patient underwent surgical resection of the mass through a combined approach; the existing cervical incision and a right posterolateral mini-thoracotomy. The postoperative course of the patient was uncomplicated. One year after surgery, the patient is asymptomatic and disease-free. (Folia Morphol 2018; 77, 1: 166–169

    Unilateral hypertransparency on chest radiograph: the congenital Poland Syndrome

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      Unilateral hypertransparent hemithorax requires a particular diagnostic approach as it can be the result of diverse pulmonary diseases, including pneumothorax, large pulmonary embolus, unilateral large bullae, mucous plag, airway obstruction and contralateral pleural effusion. Congenital syndromes with chest wall abnormalities, are rare, but often underdiagnosed causes. Poland Syndrome consists of such a rare, congenital anomaly and is characterized by the absence of the pectoralis major muscle and upper limb ipsilateral abnormalities. We present a case of a patient with acute exacerbation of chronic obstructive pulmonary disease (COPD) and a unilateral hypertransparency on chest radiology, attributed to the underlying Poland Syndrome.  

    A systematic investigation of the intrinsic flow properties of fractures using a combined 3D printing and micro-computed tomography approach

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    Geological storage operations spanning energy, nuclear material and carbon dioxide (CO2) storage, require meticulous understanding of the integrity of geological seals over a range of temporal and spatial scales. Fluid-conductive fault and fracture systems in otherwise low-permeability rocks may threaten seal performance and compromise subsurface storage projects. The understanding of these systems is complicated by the occurrence of anisotropic aperture distribution caused by inherent surface roughness. Difficulties predicting fluid flow through fractures stems from our limited understanding of the fundamental controls on their intrinsic permeabilities, and the prevalence, severity and complexity of hydromechanical responses arising from the coupling of multiphase flow, pore pressure and effective stress. In this study, we systematically investigated the effect of surface roughness on the transport properties of 3D-printed (Acrylonitrile Butadiene Styrene resin) fracture surfaces with micrometre surface roughness distributions. We printed 11 separate fractures, 7 of which are synthetically generated self-affine surfaces encompassing a range of fractal dimensions (Df = 1.2 to 2.4) observed in nature. The remaining 4 are acquired from micrometre-scale surface scans from natural fractures within the Carmel mudrock, a caprock from a natural CO2 leakage site in Utah, USA. Fluid flow experiments using single (brine) and multiple fluids (decane and brine) are undertaken to investigate the fluid pathways and interactions between each phase across a range of effective stresses (5 to 25 bar). We investigate the interplay between multiphase flow dynamics, surface roughness and hydraulic aperture distribution to gain insight into the intrinsic transport properties of fractures with different origins of roughness. Experiments are performed and imaged using a micro-computed tomography scanner (EMCT; (Bultreys et al., 2016)), where the results can be used to further the understanding of the governing parameters influencing fracture transmissivity, while also constraining surface roughness inputs for single- and multiphase fracture flow models

    Transpiration Induces Radial Turgor Pressure Gradients in Wheat and Maize Roots

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    Jednostronnie jasne płuco na radiogramie klatki piersiowej — wrodzony zespół Polanda

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    Zwiększenie przejrzystości jednego płuca wymaga wdrożenia szczególnych procedur diagnostycznych, ponieważ przyczyną takiego stanu może być wiele różnorodnych chorób układu oddechowego, włączając odmę opłucnową, masywny zator płucny, duży jednostronny pęcherz rozedmowy, czop śluzowy, zamknięcie dużego oskrzela oraz płyn w przeciwległej jamie opłucnowej. Wrodzone zaburzenia budowy ściany klatki piersiowej należą do rzadkich, choć często niezdiagnozowanych przyczyn. Zespół Polanda należy do takich rzadkich wrodzonych anomalii i polega na niewykształceniu mięśnia piersiowego większego i nieprawidłowościach budowy kończyny górnej po tej samej stronie. W pracy przedstawiono przypadek chorego z zaostrzeniem przewlekłej obturacyjnej choroby płuc (POChP) i obrazem jednostronnie jasnego płuca na radiogramie klatki piersiowej, spowodowanym zespołem Polanda.Zwiększenie przejrzystości jednego płuca wymaga wdrożenia szczególnych procedur diagnostycznych, ponieważ przyczyną takiego stanu może być wiele różnorodnych chorób układu oddechowego, włączając odmę opłucnową, masywny zator płucny, duży jednostronny pęcherz rozedmowy, czop śluzowy, zamknięcie dużego oskrzela oraz płyn w przeciwległej jamie opłucnowej. Wrodzone zaburzenia budowy ściany klatki piersiowej należą do rzadkich, choć często niezdiagnozowanych przyczyn. Zespół Polanda należy do takich rzadkich wrodzonych anomalii i polega na niewykształceniu mięśnia piersiowego większego i nieprawidłowościach budowy kończyny górnej po tej samej stronie. W pracy przedstawiono przypadek chorego z zaostrzeniem przewlekłej obturacyjnej choroby płuc (POChP) i obrazem jednostronnie jasnego płuca na radiogramie klatki piersiowej, spowodowanym zespołem Polanda
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