1,695 research outputs found
Electrostatics of ions inside the nanopores and trans-membrane channels
A model of a finite cylindrical ion channel through a phospholipid membrane
of width separating two electrolyte reservoirs is studied. Analytical
solution of the Poisson equation is obtained for an arbitrary distribution of
ions inside the trans-membrane pore. The solution is asymptotically exact in
the limit of large ionic strength of electrolyte on the two sides of membrane.
However, even for physiological concentrations of electrolyte, the
electrostatic barrier sizes found using the theory are in excellent agreement
with the numerical solution of the Poisson equation. The analytical solution is
used to calculate the electrostatic potential energy profiles for pores
containing charged protein residues. Availability of a semi-exact interionic
potential should greatly facilitate the study of ionic transport through
nanopores and ion channels
Asymptotics and local constancy of characters of p-adic groups
In this paper we study quantitative aspects of trace characters
of reductive -adic groups when the representation varies. Our approach
is based on the local constancy of characters and we survey some other related
results. We formulate a conjecture on the behavior of relative to
the formal degree of , which we are able to prove in the case where
is a tame supercuspidal. The proof builds on J.-K.~Yu's construction and the
structure of Moy-Prasad subgroups.Comment: Proceedings of Simons symposium on the trace formul
Study of Mill Island ice core (East Antarctica): A sensitive site for high resolution ocean climate signals?
第2回極域科学シンポジウム 氷床コアセッション 11月16日(水) 国立極地研究所 2階大会議
Rupture of multiple parallel molecular bonds under dynamic loading
Biological adhesion often involves several pairs of specific receptor-ligand
molecules. Using rate equations, we study theoretically the rupture of such
multiple parallel bonds under dynamic loading assisted by thermal activation.
For a simple generic type of cooperativity, both the rupture time and force
exhibit several different scaling regimes. The dependence of the rupture force
on the number of bonds is predicted to be either linear, like a square root or
logarithmic.Comment: 8 pages, 2 figure
The 10 sea urchin receptor for egg jelly proteins (SpREJ) are members of the polycystic kidney disease-1 (PKD1) family
<p>Abstract</p> <p>Background</p> <p>Mutations in the human polycystic kidney disease-1 (<it>hPKD1</it>) gene result in ~85% of cases of autosomal dominant polycystic kidney disease, the most frequent human monogenic disease. PKD1 proteins are large multidomain proteins involved in a variety of signal transduction mechanisms. Obtaining more information about members of the PKD1 family will help to clarify their functions. Humans have five hPKD1 proteins, whereas sea urchins have 10. The PKD1 proteins of the sea urchin, <it>Strongylocentrotus purpuratus</it>, are referred to as the Receptor for Egg Jelly, or SpREJ proteins. The SpREJ proteins form a subfamily within the PKD1 family. They frequently contain C-type lectin domains, PKD repeats, a REJ domain, a GPS domain, a PLAT/LH2 domain, 1–11 transmembrane segments and a C-terminal coiled-coil domain.</p> <p>Results</p> <p>The 10 full-length SpREJ cDNA sequences were determined. The secondary structures of their deduced proteins were predicted and compared to the five human hPKD1 proteins. The genomic structures of the 10 SpREJs show low similarity to each other. All 10 SpREJs are transcribed in either embryos or adult tissues. SpREJs show distinct patterns of expression during embryogenesis. Adult tissues show tissue-specific patterns of SpREJ expression.</p> <p>Conclusion</p> <p>Possession of a REJ domain of about 600 residues defines this family. Except for SpREJ1 and 3, that are thought to be associated with the sperm acrosome reaction, the functions of the other SpREJ proteins remain unknown. The sea urchin genome is one-fourth the size of the human genome, but sea urchins have 10 SpREJ proteins, whereas humans have five. Determination of the tissue specific function of each of these proteins will be of interest to those studying echinoderm development. Sea urchins are basal deuterostomes, the line of evolution leading to the vertebrates. The study of individual PKD1 proteins will increase our knowledge of the importance of this gene family.</p
Measurement of one-particle correlations and momentum distributions for trapped 1D gases
van Hove's theory of scattering of probe particles by a macroscopic target is
generalized so as to relate the differential cross section for atomic ejection
via stimulated Raman transitions to one-particle momentum-time correlations and
momentum distributions of 1D trapped gases. This method is well suited to
probing the longitudinal momentum distributions of 1D gases in situ, and
examples are given for bosonic and fermionic atoms.Comment: 4 pages, 2 .eps figure
Irreducible characters of GSp(4, q) and dimensions of spaces of fixed vectors
In this paper, we compute the conjugacy classes and the list of irreducible
characters of GSp(4,q), where q is odd. We also determine precisely which
irreducible characters are non-cuspidal and which are generic. These characters
are then used to compute dimensions of certain subspaces of fixed vectors of
smooth admissible non-supercuspidal representations of GSp(4,F), where F is a
non-archimedean local field of characteristic zero with residue field of order
q.Comment: 48 pages, 21 tables. Corrected an error in Table 16 for type V*
representations (theta_11 and theta_12 were switched
On the elliptic nonabelian Fourier transform for unipotent representations of p-adic groups
In this paper, we consider the relation between two nonabelian Fourier
transforms. The first one is defined in terms of the Langlands-Kazhdan-Lusztig
parameters for unipotent elliptic representations of a split p-adic group and
the second is defined in terms of the pseudocoefficients of these
representations and Lusztig's nonabelian Fourier transform for characters of
finite groups of Lie type. We exemplify this relation in the case of the p-adic
group of type G_2.Comment: 17 pages; v2: several minor corrections, references added; v3:
corrections in the table with unipotent discrete series of G
Coherent Tunneling of Atoms from Bose-condensed Gases at Finite Temperatures
Tunneling of atoms between two trapped Bose-condensed gases at finite
temperatures is explored using a many-body linear response tunneling formalism
similar to that used in superconductors. To lowest order, the tunneling
currents can be expressed quite generally in terms of the single-particle
Green's functions of the isolated Bose gases. A coherent first-order tunneling
Josephson current between two atomic Bose-condensates is found, in addition to
coherent and dissipative contributions from second-order
condensate-noncondensate and noncondensate-noncondensate tunneling. Our work is
a generalization of Meier and Zwerger, who recently treated tunneling between
uniform atomic Bose gases. We apply our formalism to the analysis of an
out-coupling experiment induced by light wave fields, using a simple
Bogoliubov-Popov quasiparticle approximation for the trapped Bose gas. For
tunneling into the vacuum, we recover the results of Japha, Choi, Burnett and
Band, who recently pointed out the usefulness of studying the spectrum of
out-coupled atoms. In particular, we show that the small tunneling current of
noncondensate atoms from a trapped Bose gas has a broad spectrum of energies,
with a characteristic structure associated with the Bogoliubov quasiparticle
u^2 and v^2 amplitudes.Comment: 26 pages, 5 figures, minor changes, to appear in PR
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