Oscillatory behavior of chromospheric fine structures in a network and a semi-active regions

In the present work, we study the periodicities of oscillations in dark fine structures using observations of a network and a semi-active region close to the solar disk center. We simultaneously obtained spatially high resolution time series of white light images and narrow band images in the H$\alpha$ line using the 2D G\"ottingen spectrometer, which were based on two Fabry-Perot interferometers and mounted in the VTT/Observatorio del Teide/Tenerife. During the observations, the H$\alpha$ line was scanned at 18 wavelength positions with steps of 125 m\AA. We computed series of Doppler and intensity images by subtraction and addition of the H$\alpha$ $\pm$ 0.3 \AA\ and $\pm$ 0.7 \AA\ pairs, sampling the upper chromosphere and the upper photosphere, respectively. Then we obtained power, coherence and phase difference spectra by performing a wavelet analysis to the Doppler fluctuations. Here, we present comparative results of oscillatory properties of dark fine structures seen in a network and a semi-active region.Comment: 8 pages, 5 figures, accepted for publication in MNRA

Sensor fusion of camera, GPS and IMU using fuzzy adaptive multiple motion models

A tracking system that will be used for augmented reality applications has two main requirements: accuracy and frame rate. The first requirement is related to the performance of the pose estimation algorithm and how accurately the tracking system can find the position and orientation of the user in the environment. Accuracy problems of current tracking devices, considering that they are low-cost devices, cause static errors during this motion estimation process. The second requirement is related to dynamic errors (the end-to-end system delay, occurring because of the delay in estimating the motion of the user and displaying images based on this estimate). This paper investigates combining the vision-based estimates with measurements from other sensors, GPS and IMU, in order to improve the tracking accuracy in outdoor environments. The idea of using Fuzzy Adaptive Multiple Models was investigated using a novel fuzzy rule-based approach to decide on the model that results in improved accuracy and faster convergence for the fusion filter. Results show that the developed tracking system is more accurate than a conventional GPS–IMU fusion approach due to additional estimates from a camera and fuzzy motion models. The paper also presents an application in cultural heritage context running at modest frame rates due to the design of the fusion algorithm

Role of Porphyromonas gingivalis gingipains in multi-species biofilm formation

BackgroundPeriodontal diseases are polymicrobial diseases that cause the inflammatory destruction of the tooth-supporting (periodontal) tissues. Their initiation is attributed to the formation of subgingival biofilms that stimulate a cascade of chronic inflammatory reactions by the affected tissue. The Gram-negative anaerobes Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola are commonly found as part of the microbiota of subgingival biofilms, and they are associated with the occurrence and severity of the disease. P. gingivalis expresses several virulence factors that may support its survival, regulate its communication with other species in the biofilm, or modulate the inflammatory response of the colonized host tissue. The most prominent of these virulence factors are the gingipains, which are a set of cysteine proteinases (either Arg-specific or Lys-specific). The role of gingipains in the biofilm-forming capacity of P. gingivalis is barely investigated. Hence, this in vitro study employed a biofilm model consisting of 10 ¿subgingival¿ bacterial species, incorporating either a wild-type P. gingivalis strain or its derivative Lys-gingipain and Arg-gingipan isogenic mutants, in order to evaluate quantitative and qualitative changes in biofilm composition.ResultsFollowing 64 h of biofilm growth, the levels of all 10 species were quantified by fluorescence in situ hybridization or immunofluorescence. The wild-type and the two gingipain-deficient P. gingivalis strains exhibited similar growth in their corresponding biofilms. Among the remaining nine species, only the numbers of T. forsythia were significantly reduced, and only when the Lys-gingipain mutant was present in the biofilm. When evaluating the structure of the biofilm by confocal laser scanning microscopy, the most prominent observation was a shift in the spatial arrangement of T. denticola, in the presence of P. gingivalis Arg-gingipain mutant.ConclusionsThe gingipains of P. gingivalis may qualitatively and quantitatively affect composition of polymicrobial biofilms. The present experimental model reveals interdependency between the gingipains of P. gingivalis and T. forsythia or T. denticola

Porphyry Cu-Mo-(Au) Mineralization at Paraga Area, Nakhchivan District, Azerbaijan: Evidence from Mineral Paragenesis, Hyrothermal Alteration and Geochemical Studies

The Paraga area is located at the extreme eastern part of Nakhchivan district at the boundary with Armenia. The field study is situated at Ordubad region placed in 9 km from Paraga village and stays at 2300-2800 m height over sea level. It lies within a region of low-grade metamorphic porphyritic volcanic and plutonic rocks. The detailed field studies revealed that this area composed mainly of metagabbro-diorite intrusive rocks with porphyritic character emplaced into meta-andesitic rocks. This complex is later intruded by unmapped olivine gabbroic rocks. The Cu-Mo-(Au) mineralization at Paraga deposit is vein-type mineralization that is essentially related to quartz veins stockwork which cut the dioritic rocks and concentrated at the eastern and northeastern parts of the area with different directions N80W, N25W, N70E and N45E. Also, this mineralization is associated with two shearing zones directed N75W and N15E. The host porphyritic rocks were affected by intense sulfidation, carbonatization, sericitization and silicification with pervasive hematitic alterations accompanied with mineralized quartz veins and quartz-carbonate veins. Sulfide minerals which are chalcopyrite, pyrite, arsenopyrite and sphalerite occurred in two cases either inside these mineralized quartz veins or disseminated in the highly altered rocks as well as molybdenite and also at the peripheries between the altered host rock and veins. Gold found as inclusion disseminated in arsenopyrite and pyrite as well as in their cracks

Porphyry Cu-Mo-(Au) Mineralization at Paraga Area, Nakhchivan District, Azerbaijan: Evidence from Mineral Paragenesis, Hyrothermal Alteration and Geochemical Studies

The Paraga area is located at the extreme eastern part of Nakhchivan district at the boundary with Armenia. The field study is situated at Ordubad region placed in 9 km from Paraga village and stays at 2300-2800 m height over sea level. It lies within a region of low-grade metamorphic porphyritic volcanic and plutonic rocks. The detailed field studies revealed that this area composed mainly of metagabbro-diorite intrusive rocks with porphyritic character emplaced into meta-andesitic rocks. This complex is later intruded by unmapped olivine gabbroic rocks. The Cu-Mo-(Au) mineralization at Paraga deposit is vein-type mineralization that is essentially related to quartz veins stockwork which cut the dioritic rocks and concentrated at the eastern and northeastern parts of the area with different directions N80W, N25W, N70E and N45E. Also, this mineralization is associated with two shearing zones directed N75W and N15E. The host porphyritic rocks were affected by intense sulfidation, carbonatization, sericitization and silicification with pervasive hematitic alterations accompanied with mineralized quartz veins and quartz-carbonate veins. Sulfide minerals which are chalcopyrite, pyrite, arsenopyrite and sphalerite occurred in two cases either inside these mineralized quartz veins or disseminated in the highly altered rocks as well as molybdenite and also at the peripheries between the altered host rock and veins. Gold found as inclusion disseminated in arsenopyrite and pyrite as well as in their cracks

Impact of aging on TREM-1 responses in the periodontium: a cross-sectional study in an elderly population

BACKGROUND: Aging is associated with altered immune response, which increases susceptibility to infections. sTREM-1 is involved in the amplification of the inflammatory response to bacterial infection. The present cross-sectional study aims to investigate local sTREM-1 levels in gingival crevicular fluid (GCF) as well as key periodontal pathogen levels in the subgingival plaque in an elderly cohort with periodontal health, gingivitis, and chronic periodontitis (CP). METHODS: Subjects were 51 systemically healthy, elderly individuals (mean age, 68 ± 4.5 years) who had undergone full-mouth periodontal examinations. Subgingival plaque and GCF samples were collected from the healthy sites of participants without periodontal disease (n = 17), the sites with gingival inflammation from patients with gingivitis (n = 19), and the periodontitis sites of patients with CP (n = 15). GCF volumes were measured by an electronic impedance device, and total protein levels were assessed by a flouremetric assay. sTREM-1 levels in GCF were measured by enzyme-linked immunosorbent assay. The subgingival plaque total bacteria, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Fusobacterium nucleatum, and Prevotella intermedia levels were determined by quantitative real-time polymerase chain reaction. Statistical analysis was performed using nonparametric methods. RESULTS: GCF volume, total protein concentrations, and sTREM-1 levels in GCF were similar among the groups (p > 0.05). Significantly higher T. forsythia levels were observed in subgingival plaque samples harvested from patients with gingivitis and CP, than in those from healthy participants (p < 0.05). However, the subgingival levels of the other four periodontal pathogens and total bacteria were not statistically different among the groups (p > 0.05). CONCLUSIONS: Our findings suggest that there are no differences in GCF volume, total protein, and sTREM-1 levels between healthy and periodontally diseased elderly adults. We found only limited differences in the studied subgingival microbial profile. This finding indicates an already deregulated, local inflammatory response in this elderly cohort, on which bacterial biofilm challenge may have a limited further impact

Sectored DRAM: A Practical Energy-Efficient and High-Performance Fine-Grained DRAM Architecture

We propose Sectored DRAM, a new, low-overhead DRAM substrate that reduces wasted energy by enabling fine-grained DRAM data transfers and DRAM row activation. Sectored DRAM leverages two key ideas to enable fine-grained data transfers and row activation at low chip area cost. First, a cache block transfer between main memory and the memory controller happens in a fixed number of clock cycles where only a small portion of the cache block (a word) is transferred in each cycle. Sectored DRAM augments the memory controller and the DRAM chip to execute cache block transfers in a variable number of clock cycles based on the workload access pattern with minor modifications to the memory controller's and the DRAM chip's circuitry. Second, a large DRAM row, by design, is already partitioned into smaller independent physically isolated regions. Sectored DRAM provides the memory controller with the ability to activate each such region based on the workload access pattern via small modifications to the DRAM chip's array access circuitry. Activating smaller regions of a large row relaxes DRAM power delivery constraints and allows the memory controller to schedule DRAM accesses faster. Compared to a system with coarse-grained DRAM, Sectored DRAM reduces the DRAM energy consumption of highly-memory-intensive workloads by up to (on average) 33% (20%) while improving their performance by up to (on average) 36% (17%). Sectored DRAM's DRAM energy savings, combined with its system performance improvement, allows system-wide energy savings of up to 23%. Sectored DRAM's DRAM chip area overhead is 1.7% the area of a modern DDR4 chip. We hope and believe that Sectored DRAM's ideas and results will help to enable more efficient and high-performance memory systems. To this end, we open source Sectored DRAM at https://github.com/CMU-SAFARI/Sectored-DRAM.Comment: Extended version of paper that is to appear in ACM Transactions on Architecture and Code Optimization (ACM TACO

Functionally-Complete Boolean Logic in Real DRAM Chips: Experimental Characterization and Analysis

Processing-using-DRAM (PuD) is an emerging paradigm that leverages the analog operational properties of DRAM circuitry to enable massively parallel in-DRAM computation. PuD has the potential to reduce or eliminate costly data movement between processing elements and main memory. Prior works experimentally demonstrate three-input MAJ (MAJ3) and two-input AND and OR operations in commercial off-the-shelf (COTS) DRAM chips. Yet, demonstrations on COTS DRAM chips do not provide a functionally complete set of operations. We experimentally demonstrate that COTS DRAM chips are capable of performing 1) functionally-complete Boolean operations: NOT, NAND, and NOR and 2) many-input (i.e., more than two-input) AND and OR operations. We present an extensive characterization of new bulk bitwise operations in 256 off-the-shelf modern DDR4 DRAM chips. We evaluate the reliability of these operations using a metric called success rate: the fraction of correctly performed bitwise operations. Among our 19 new observations, we highlight four major results. First, we can perform the NOT operation on COTS DRAM chips with a 98.37% success rate on average. Second, we can perform up to 16-input NAND, NOR, AND, and OR operations on COTS DRAM chips with high reliability (e.g., 16-input NAND, NOR, AND, and OR with an average success rate of 94.94%, 95.87%, 94.94%, and 95.85%, respectively). Third, data pattern only slightly affects bitwise operations. Our results show that executing NAND, NOR, AND, and OR operations with random data patterns decreases the success rate compared to all logic-1/logic-0 patterns by 1.39%, 1.97%, 1.43%, and 1.98%, respectively. Fourth, bitwise operations are highly resilient to temperature changes, with small success rate fluctuations of at most 1.66% when the temperature is increased from 50C to 95C. We open-source our infrastructure at https://github.com/CMU-SAFARI/FCDRAMComment: A shorter version of this work is to appear at the 30th IEEE International Symposium on High-Performance Computer Architecture (HPCA-30), 202