A Comparison of Measured and Predicted Haemoglobin Genotype in a Nigerian Population in Bonny, Rivers State, Nigeria

Cellulose acetate electrophoresis technique has been used to estimate haemoglobin genotype and the predicted values from the estimate in accordance with the population genetics studies (Fleming and Lehman1982) were evaluated in 850 subjects (386 males and 464 females) selected randomly from Bonny, in Rivers State, Nigeria of ages between 3 and 77 years. There was significant differences (P < 0.001) between the measured and the predicted haemoglobin genotype values suggesting that the predicted cannot be substituted for the measured. Two further haemoglobinopatheis, HbSC and HbCC were predicted to be the expected haemoglobin genotype of newborn into the population in the next decade suggesting that the incidence of abnormal haemoglobin in the population may arise from the complex interaction between the genetic constitution of the individual and some unidentified environmental factors

A Comparison of Measured and Predicted Haemoglobin Genotype in a Nigerian Population in Bonny, Rivers State, Nigeria

Cellulose acetate electrophoresis technique has been used to estimate haemoglobin genotype and the predicted values from the estimate in accordance with the population genetics studies (Fleming and Lehman 1982) were evaluated in 850 subjects (386 males and 464 females) selected randomly from Bonny, in Rivers State, Nigeria of ages between 3 and 77 years. There was significant differences (P < 0.001) between the measured and the predicted haemoglobin genotype values suggesting that the predicted cannot be substituted for the measured. Two further haemoglobinopatheis, HbSC and HbCC were predicted to be the expected haemoglobin genotype of newborn into the population in the next decade suggesting that the incidence of abnormal haemoglobin in the population may arise from the complex interaction between the genetic constitution of the individual and some unidentified environmental factors. @ JASE

A Comparison of Measured and Predicted Haemoglobin Genotype in a Nigerian Population in Bonny, Rivers State, Nigeria

Cellulose acetate electrophoresis technique has been used to estimate haemoglobin genotype and the predicted values from the estimate in accordance with the population genetics studies (Fleming and Lehman 1982) were evaluated in 850 subjects (386 males and 464 females) selected randomly from Bonny, in Rivers State, Nigeria of ages between 3 and 77 years. There was significant differences (P < 0.001) between the measured and the predicted haemoglobin genotype values suggesting that the predicted cannot be substituted for the measured. Two further haemoglobinopatheis, HbSC and HbCC were predicted to be the expected haemoglobin genotype of newborn into the population in the next decade suggesting that the incidence of abnormal haemoglobin in the population may arise from the complex interaction between the genetic constitution of the individual and some unidentified environmental factors. @ JASEM The percentage of person with one of two types of haemoglobin genes – normal haemoglobin (HbAA) and abnormal haemoglobin (sickle cell trait, HbAS, sickle cell disease HbSS etc) in a community is an indication of Health awareness of its population. Knowledge and care of whether one is a carrier or a sickler or have normal haemoglobin is therefore the responsibility of the person and the entire community. Available reports indicate important differences in the distribution of haemoglobin genotypes between Causcasians and Africans (Schnelder et al 1976, Graham 1988, Reid and Famodu, 1988, Fleming and Lehman 1982). The most prominent feature is the prevalence of sickle cell trait/sickle cell disease among Africans than Caucasians and this correlates with falciparium malaria parasite transmission theory (Allison, 1964). There is however, a limited number of information of studies which described the distribution of haemoglobin genotypes among Nigerian population, in particularly, for a ethnic group in the swampy environment of the Niger Delta. The present report is, therefore, a study designed to find out the frequency of haemoglobin genotype in the population of Bonny ethnic group in the Niger Delta from which further information about the pattern of distribution of normal and abnormal haemoglobin genotypes for Nigerian may emerge. The Hardy-Weinbery law (Fleming and Lehman, 1982) has been used to predict the expected distribution of haemoglobin genotype of newborn into the population in the next decade

Multi-criteria evaluation of sources for self-help domestic water supply

Abstract Two multi-criteria decision analysis methods were employed to evaluate six water sources. The analytical hierarchical process (AHP) ranked borehole highest with a rank of 0.321 followed by water board with a rank of 0.284. The other sources ranked far below these two as follows: water tanker (0.139), rainwater harvesting (0.117), shallow well (0.114) and stream (0.130). The Technique for Order Performance by Similarity to the Ideal Solution (TOPSIS) ranked water board highest with a rank of 0.865, followed by borehole with a value of 0.778. Quality and risk of contamination were found to be the most influential criteria while seasonality was the least

Physico-chemical changes in velvet tamarind (Dialium guineense Wild) during fruit development and ripening

Some physical and chemical changes in velvet tamarind (Dialium guineense wild) fruits during development (5th to 11th week), maturation (11th to 13th week) and ripening (13th to 17th week) were studied. The properties investigated during these periods included pod weight, pod diameter, percent fruit portions, sugar and acid composition of the velvet tamarind pulp. Steady changes were recorded in both physical and chemical properties at different stages of fruit development. The single pod weight and diameter increased from mean values of 0.35g and 0.57cm at the 5th week to values of 0.61g and 1.39cm respectively at ripening. The fruit portions maintained steady proportions of about 40%, 37% and 21% for shell, pulp and seed respectively. The values for percent carbohydrate, ethanol soluble sugars and total soluble solids increased significantly (p>0.05) throughout the period of the study, from the 5th week values of 5.80%, 5.30% and 6.25°Brix to values of 35.92%, 29.21%, and 40.01°Brix respectively at ripening (17th week). The sugars identified were glucose, fructose, maltose and sucrose. The titratable acidity increased gradually at first from a value of 1.09% at the 5th week to 3.85% at the 11th week. It then decreased to a value of 3.67% at the 13th week before it rose to a final value to 4.50% at ripening (17th week). The acids identified were tartaric, citric, malic and ascorbic acids. It was observed that the peak period for most acids, sugars and other soluble solids (which are important for the desired flavour of the fruit) is the 17th week. Keywords: velvet tamarind, fruit, development, Rrpening, acids, sugars, maturityNigerian Food Journal Vol. 23 2005: 133-13

Physico-chemical changes in velvet tamarind (Dialium guineense Wild) during fruit development and ripening

Some physical and chemical changes in velvet tamarind (Dialium guineense wild) fruits during development (5th to 11th week), maturation (11th to 13th week) and ripening (13th to 17th week) were studied. The properties investigated during these periods included pod weight, pod diameter, percent fruit portions, sugar and acid composition of the velvet tamarind pulp. Steady changes were recorded in both physical and chemical properties at different stages of fruit development. The single pod weight and diameter increased from mean values of 0.35g and 0.57cm at the 5th week to values of 0.61g and 1.39cm respectively at ripening. The fruit portions maintained steady proportions of about 40%, 37% and 21% for shell, pulp and seed respectively. The values for percent carbohydrate, ethanol soluble sugars and total soluble solids increased significantly (p>0.05) throughout the period of the study, from the 5th week values of 5.80%, 5.30% and 6.25°Brix to values of 35.92%, 29.21%, and 40.01°Brix respectively at ripening (17th week). The sugars identified were glucose, fructose, maltose and sucrose. The titratable acidity increased gradually at first from a value of 1.09% at the 5th week to 3.85% at the 11th week. It then decreased to a value of 3.67% at the 13th week before it rose to a final value to 4.50% at ripening (17th week). The acids identified were tartaric, citric, malic and ascorbic acids. It was observed that the peak period for most acids, sugars and other soluble solids (which are important for the desired flavour of the fruit) is the 17th week. Keywords: velvet tamarind, fruit, development, Rrpening, acids, sugars, maturityNigerian Food Journal Vol. 23 2005: 133-13

Effects of processing on the proximate and sensory quality of ‘oze\' (Bosqueia angolensis) seeds

No Abstract.International Journal of Tropical Agriculture and Food Systems Vol. 2 (1) 2008: pp. 77-8