Developing Organ Offer and Acceptance Measures: When ‘Good’ Organs Are Turned Down

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75521/1/j.1600-6143.2007.01784.x.pd

Kidney and pancreas transplantation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106710/1/j.1600-6135.2004.00399.x.pd

Decision making in kidney paired donation programs with altruistic donors

In recent years, kidney paired donation has been extended to include living non-directed or altruistic donors, in which an altruistic donor donates to the candidate of an incompatible donor candidate pair with the understanding that the donor in that pair will further donate to the candidate of a second pair, and so on; such a process continues and thus forms an altruistic donor-initiated chain. In this paper, we propose a novel strategy to sequentially allocate the altruistic donor (or bridge donor) so as to maximize the expected utility; analogous to the way a computer plays chess, the idea is to evaluate different allocations for each altruistic donor (or bridge donor) by looking several moves ahead in a derived look-ahead search tree. Simulation studies are provided to illustrate and evaluate our proposed method

Planning for Uncertainty and Fallbacks Can Increase the Number of Transplants in a Kidney‐Paired Donation Program

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/113739/1/ajt13413.pd

Transplanting Kidneys Without Points for HLA‐B Matching: Consequences of the Policy Change

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87103/1/j.1600-6143.2011.03606.x.pd

Association of Center Volume with Outcome After Liver and Kidney Transplantation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73934/1/j.1600-6143.2004.00462.x.pd

Health‐Related Quality of Life in Kidney Donors From the Last Five Decades: Results From the RELIVE Study

Live donation benefits recipients, but the long‐term consequences for donors remain uncertain. Renal and Lung Living Donors Evaluation Study surveyed kidney donors (N = 2455; 61% women; mean age 58, aged 24–94; mean time from donation 17 years, range 5–48 years) using the Short Form‐36 Health Survey (SF‐36). The 95% confidence intervals for White and African‐American donors included or exceeded SF‐36 norms. Over 80% of donors reported average or above average health for their age and sex (p 1 SD below norm). Obesity, history of psychiatric difficulties and non‐White race were risk factors for impaired physical health; history of psychiatric difficulties was a risk factor for impaired mental health. Education, older donation age and a first‐degree relation to the recipient were protective factors. One percent reported that donation affected their health very negatively. Enhanced predonation evaluation and counseling may be warranted, along with ongoing monitoring for overweight donors. Questionnaires completed by 2544 living donors 5 to 48 years postnephrectomy show that 80% have average or better health‐related quality of life for their age and sex based on SF‐36 norms and that obesity, history of psychiatric difficulties and nonwhite race are risk factors for poor health‐related quality of life outcomes, whereas being older, having more education and/or being a first‐degree relation to the recipient predict better outcomes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/100300/1/ajt12434.pd

Access and Outcomes Among Minority Transplant Patients, 1999–2008, with a Focus on Determinants of Kidney Graft Survival

Coincident with an increasing national interest in equitable health care, a number of studies have described disparities in access to solid organ transplantation for minority patients. In contrast, relatively little is known about differences in posttransplant outcomes between patients of specific racial and ethnic populations. In this paper, we review trends in access to solid organ transplantation and posttransplant outcomes by organ type, race and ethnicity. In addition, we present an analysis of categories of factors that contribute to the racial/ethnic variation seen in kidney transplant outcomes. Disparities in minority access to transplantation among wait-listed candidates are improving, but persist for those awaiting kidney, simultaneous kidney and pancreas and intestine transplantation. In general, graft and patient survival among recipients of solid organ transplants is highest for Asians and Hispanic/Latinos, intermediate for whites and lowest for African Americans. Although much of the difference in outcomes between racial/ethnic groups can be accounted for by adjusting for patient characteristics, important observed differences remain. Age and duration of pretransplant dialysis exposure emerge as the most important determinants of survival in an investigation of the relative impact of center-related versus patient-related variables on kidney graft outcomes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79270/1/j.1600-6143.2009.03009.x.pd

Repeat Organ Transplantation in the United States, 1996–2005

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72698/1/j.1600-6143.2007.01786.x.pd