44 research outputs found
Study of areas and development strategy for regional planning in East Pakistan.
Massachusetts Institute of Technology. Dept. of City and Regional Planning. Thesis. 1965. M.C.P.Bibliography: leaves 178-180.M.C.P
A Proposed Model for Developing Creative Leadership Practices for Managers of Inclusive Educational Institutions in Jordan
The paper contributes to the existing literature to know the degree to which principals of inclusive educational institutions in Jordan practice creative leadership from their point of view. Building a proposed vision to develop creative leadership practices for the principals of inclusive educational institutions in Jordan, from their point of view. According to the variable of gender, educational qualification, experience, and the study used the descriptive approach. The study sample consisted of (46) male and female managers. A questionnaire consisting of (5) dimensions and (41) indicators distributed over the dimensions of the scale was used. Its validity and reliability were confirmed. The results indicated that the total score on the dimensions of the tool as a whole was low. The results also showed that there are statistically significant differences due to the gender variable in favor of males, and there are no statistically significant differences due to the effect of educational qualification and experience
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RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins
In higher eukaryotes, most mRNAs that encode secreted or membrane-bound proteins contain elements that promote an alternative mRNA nuclear export (ALREX) pathway. Here we report that ALREX-promoting elements also potentiate translation in the presence of upstream nuclear factors. These RNA elements interact directly with, and likely co-evolved with, the zinc finger repeats of RanBP2/Nup358, which is present on the cytoplasmic face of the nuclear pore. Finally we show that RanBP2/Nup358 is not only required for the stimulation of translation by ALREX-promoting elements, but is also required for the efficient global synthesis of proteins targeted to the endoplasmic reticulum (ER) and likely the mitochondria. Thus upon the completion of export, mRNAs containing ALREX-elements likely interact with RanBP2/Nup358, and this step is required for the efficient translation of these mRNAs in the cytoplasm. ALREX-elements thus act as nucleotide platforms to coordinate various steps of post-transcriptional regulation for the majority of mRNAs that encode secreted proteins
Genome Analysis Reveals Interplay between 5′UTR Introns and Nuclear mRNA Export for Secretory and Mitochondrial Genes
In higher eukaryotes, messenger RNAs (mRNAs) are exported from the nucleus to the cytoplasm via factors deposited near the 5′ end of the transcript during splicing. The signal sequence coding region (SSCR) can support an alternative mRNA export (ALREX) pathway that does not require splicing. However, most SSCR–containing genes also have introns, so the interplay between these export mechanisms remains unclear. Here we support a model in which the furthest upstream element in a given transcript, be it an intron or an ALREX–promoting SSCR, dictates the mRNA export pathway used. We also experimentally demonstrate that nuclear-encoded mitochondrial genes can use the ALREX pathway. Thus, ALREX can also be supported by nucleotide signals within mitochondrial-targeting sequence coding regions (MSCRs). Finally, we identified and experimentally verified novel motifs associated with the ALREX pathway that are shared by both SSCRs and MSCRs. Our results show strong correlation between 5′ untranslated region (5′UTR) intron presence/absence and sequence features at the beginning of the coding region. They also suggest that genes encoding secretory and mitochondrial proteins share a common regulatory mechanism at the level of mRNA export
¿Cómo se llamaban los edificios andalusÃes? La evolución denominativa de los palacios de Comares y de los Leones en la Alhambra
Enhancement of silicon nanowire micro-TEG using a plasmonic mid-IR absorber
[abstract not available
Comparative bioacoustic studies in the Yellow-bellied toad, Bombina varietaga (L.), and relationships of European and Asian species and subspecies of the genus Bombina (Anura, Amphibia)
Volume: 37Start Page: 49End Page: 6
Photon harvesting and light trapping in pentacene and PTCDI-C13H27 for organic solar cell application
The deep understanding of optical and spectroscopic properties of organic semiconductors is essential for designing the organic photovoltaic solar cells (OSCs) and estimating their prospect performance. In this work, the optoelectronic properties of pentacene and PTCDI-C13H27 conjugated molecules were estimated using density function theory (DFT) calculations. Hence, the parameters of energy gaps, charge transfer (CT), open circuit voltage (VOC), reorganization energy and light harvesting efficiency (LHE) have been extracted using the DFT at B3LYP/6-311G(d,p) level. The results predicted that pentacene and PTCDI-C13H27 molecules possess an efficient broad-band photon harvesting over the visible spectrum with absorption maximum at 643 and 514.5 nm respectively. Moreover, the light trapping inside the pentacene and PTCDI-C13H27 layers integrated in a proposed OSC have been studied using 3D finite difference time domain (FDTD) model. The optimum thickness of the OSC layers were evaluated based on their absorption capability