The Inductive Single-Electron Transistor (L-SET)

We demonstrate a sensitive method of charge detection based on radio-frequency readout of the Josephson inductance of a superconducting single-electron transistor. Charge sensitivity $1.4 \times 10^{-4}e/\sqrt{Hz}$, limited by preamplifier, is achieved in an operation mode which takes advantage of the nonlinearity of the Josephson potential. Owing to reactive readout, our setup has more than two orders of magnitude lower dissipation than the existing method of radio-frequency electrometry. With an optimized sample, we expect uncoupled energy sensitivity below $\hbar$ in the same experimental scheme.Comment: 10 page

Quantum capacitive phase detector

We discuss how a single Cooper-pair transistor may be used to detect the superconducting phase difference by using the phase dependence of the input capacitance from gate to the ground. The proposed device has a low power dissipation because its operation is in principle free from quasiparticle generation. According to the sensitivity estimates the device may be used for efficient qubit readout in a galvanically isolated and symmetrized circuit.Comment: 5 pages, published for

Estimation of dynamic SNP-heritability with Bayesian Gaussian process models

Motivation: Improved DNA technology has made it practical to estimate single nucleotide polymorphism (SNP)-heritability among distantly related individuals with unknown relationships. For growth and development related traits, it is meaningful to base SNP-heritability estimation on longitudinal data due to the time-dependency of the process. However, only few statistical methods have been developed so far for estimating dynamic SNP-heritability and quantifying its full uncertainty. / Results: We introduce a completely tuning-free Bayesian Gaussian process (GP) based approach for estimating dynamic variance components and heritability as their function. For parameter estimation, we use a modern Markov Chain Monte Carlo (MCMC) method which allows full uncertainty quantification. Several data sets are analysed and our results clearly illustrate that the 95 % credible intervals of the proposed joint estimation method (which "borrows strength" from adjacent time points) are significantly narrower than of a two-stage baseline method that first estimates the variance components at each time point independently and then performs smoothing. We compare the method with a random regression model using MTG2 and BLUPF90 softwares and quantitative measures indicate superior performance of our method. Results are presented for simulated and real data with up to 1000 time points. Finally, we demonstrate scalability of the proposed method for simulated data with tens of thousands of individuals. / Availability: The C++ implementation dynBGP and simulated data are available in GitHub (https://github.com/aarjas/dynBGP). The programs can be run in R. Real datasets are available in QTL archive (https://phenome.jax.org/centers/QTLA). / Supplementary information: Supplementary data are available at Bioinformatics online

2005–2010 Multiwavelength Campaing of OJ287

The light curve of quasar OJ287 extends from 1891 up today without major gaps. This is partly due to extensive studies of historical plate archives by Rene Hudec and associates, and partly due to several observing campaigns in recent times. Here we summarize the results of the 2005–2010 observing campaign, in which several hundred scientists and amateur astronomers took part. The main results are the following: (1) The 2005 October optical outburst came at the expected time, thus confirming the General Relativistic precession in the binary black hole system, as was originally proposed bySillanp¨a¨a et al. (1988). At the same time, this result disproved the model of a single black hole system with accretion disk oscillations, as well as several toy models of binaries without relativistic precession. In the latter models the main outburst would have been a year later. No particular activity was seen in OJ287 in 2006 October. (2) The nature of the radiation of the 2005 October outburst was expected to be bremsstrahlung from hot gas at a temperature of 3 × 105 K. The reason for the outburst is a collision of the secondary on the accretion disk of the primary, which heats the gas to this temperature. This was confirmed by combined ground based and ultraviolet observations using the XMM-Newton X-ray telescope. (3) A secondary outburst of the same nature was expected at 2007 September 13. Within the accuracy of the observations (about 6 hours), it started at the correct time. Thus the prediction was accurate at the same level as the prediction of the return of Halley’s comet in 1986. Due to the bremsstrahlung nature of the outburst, the radiation was unpolarised, as expected. (4) Further synchrotron outbursts were expected following the two bremsstrahlung outbursts.They came as scheduled between 2007 October and 2009 December. (5) Due to the effect of the secondary on the overall direction of the jet, the parsec scale jet was expected to rotate in the sky by a large angle around 2009. This rotation has been seen in high frequency radio observations. The OJ287 binary black hole system is currently our best laboratory for testing theories of gravitation. Using OJ287, the correctness of General Relativity has now been demonstrated up to second Post-Newtonian order, higher than has been possible using binary pulsars

Charge sensitivity of the Inductive Single-Electron Transistor

We calculate the charge sensitivity of a recently demonstrated device where the Josephson inductance of a single Cooper-pair transistor is measured. We find that the intrinsic limit to detector performance is set by oscillator quantum noise. Sensitivity better than $10^{-6}$e$/\sqrt{\mathrm{Hz}}$ is possible with a high $Q$-value $\sim 10^3$, or using a SQUID amplifier. The model is compared to experiment, where charge sensitivity $3 \times 10^{-5}$e$/\sqrt{\mathrm{Hz}}$ and bandwidth 100 MHz are achieved.Comment: 3 page

Redshift constraints for RGB 0136+391 and PKS 0735+178 from deep optical imaging

We present the results of deep I-band imaging of two BL Lacerate objects, RGB 0136+391 and PKS 0735+178, during an epoch when the optical nucleus was in a faint state in both targets. In PKS 0735+178 we find a significant excess over a point source, which, if fitted by the de Vaucouleurs model, corresponds to a galaxy with I = 18.64 +- 0.11 and r_eff = 1.8 +- 0.4 arcsec. Interpreting this galaxy as the host galaxy of PKS 0735+178 we derive z = 0.45 +- 0.06 using the host galaxy as a "standard candle". We also discuss the immediate optical environment of PKS 0735+178 and the identity of the MgII absorber at z = 0.424. Despite of the optimally chosen epoch and deep imaging we find the surface brightness profile of RGB 0136+391 to be consistent with a point source. By determining a lower limit for the host galaxy brightness by simulations, we derive z > 0.40 for this target.Comment: 6 pages, 5 figures, accepted for publication in Astronomy & Astrophysic