74 research outputs found

    ANALYSIS OF LIFE INSURANCE INVESTMENT COMPOSITION

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    Economic recession and global mettle down have brought the question of insurance company investment to the forefront. Growing attention has shifted to the pattern of investments by the insurance and question of how to evaluate such investments. The aim of this research is to evaluate investment compositions which are made by life insurance companies in Indonesia, as well as to know the effects on the performance of Insurance companies

    Tidal Volume Single Breath Washout of Two Tracer Gases - A Practical and Promising Lung Function Test

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    Small airway disease frequently occurs in chronic lung diseases and may cause ventilation inhomogeneity (VI), which can be assessed by washout tests of inert tracer gas. Using two tracer gases with unequal molar mass (MM) and diffusivity increases specificity for VI in different lung zones. Currently washout tests are underutilised due to the time and effort required for measurements. The aim of this study was to develop and validate a simple technique for a new tidal single breath washout test (SBW) of sulfur hexafluoride (SF(6)) and helium (He) using an ultrasonic flowmeter (USFM)

    Ventilation heterogeneity in the acinar and conductive zones of the normal ageing lung

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    Rationale: Small airways function studies in lung disease have used three promising multiple breath washout (MBW) derived indices: indices of ventilation heterogeneity in the acinar (S acin) and conductive (S cond) lung zones, and the lung clearance index (LCI). Since peripheral lung structure is known to change with age, ventilation heterogeneity is expected to be affected too. However, the age dependence of the MBW indices of ventilation heterogeneity in the normal lung is unknown. Objectives: The authors systematically investigated S acin, S cond or LCI as a function of age, testing also the robustness of these relationships across two laboratories. Methods: MBW tests were performed by never-smokers (50% men) in the age range 25e65 years, with data gathered across two laboratories (n=120 and n=60). For comparison with the literature, the phase III slopes from classical single breath washout tests were also acquired in one group (n=120). Measurements and main results: All three MBW indices consistently increased with age, representing a steady worsening of ventilation heterogeneity in the age range 25-65. Age explained 7-16% of the variability in S acin and S cond and 36% of the variability in LCI. There was a small but significant gender difference only for S acin. Classical single breath washout phase III slopes also showed age dependencies, with gender effects depending on the normalisation method used. Conclusions: With respect to the clinical response, age is a small but consistent effect that needs to be factored in when using the MBW indices for the detection of small airways abnormality in disease.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Modeling Axial Distribution of Nitric Oxide Production in Normal Subjects.

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