Ácido ursólico: un compuesto de origen natural con actividad antiviral en infecciones in vitro por rotavirus

Rotavirus (RV) es el principal agente causal de gastroenteritis aguda en niños menores de 5 años. En la Argentina las infecciones por RV son responsables de más del 1,2% de las muertes totales en este grupo etario. A partir de 2015 se ha incorporado una vacuna anti-RV como parte del calendario nacional de vacunación; sin embargo, su eficacia y seguridad continúan siendo evaluadas. El Ácido Ursólico (AU) es un triterpeno que se encuentra formando parte de la estructura de saponinas en diversas plantas. Diversos estudios han demostrado que el AU tiene actividad antiviral frente a ciertos virus. Por ello, nuestro grupo de investigación se centró en la evaluación del posible efecto antiviral del compuesto AU frente a RV, a partir de la utilización de un modelo de infección por RV in vitro, trabajando con la línea celular susceptible MA104. Nuestra hipótesis de trabajo es que el AU podría tener acción antiviral en infecciones por RV, afectando a una o más etapas de su ciclo de replicación. En primer lugar, con el fin de determinar las concentraciones de trabajo no citotóxicas del compuest

Ecological Interactions of the Sexually Deceptive Orchid Orchis Galilaea

Plant species dependent on highly specific interactions with pollinators are vulnerable to environmental change. Conservation strategies therefore require a detailed understanding of pollination ecology. This two-year study examined the interactions between the sexually deceptive orchid, Orchis galilaea, and its pollinator Lasioglossum marginatum. Relationships were investigated across three different habitats known to support O. galilaea (garrigue, oak woodland, and mixed oak/pine woodland) in Lebanon. Visitation rates to flowers were extremely low and restricted to male bees. The reproductive success of O. galilaea under ambient conditions was 29.3% (±2.4), compared to 89.0% (±2.1) in plants receiving cross-pollination by hand. No difference in reproductive success was found between habitat types, but values of reproductive success were positively correlated to the abundance of male bees. Pollination limitation can have negative impacts on the population growth of orchids, and this study provides clear evidence for more holistic approaches to habitat conservation to support specific interactions

Argumentation as Exogenous Coordination

Formal argumentation is one of the most popular approaches in modern logic and reasoning. The theory of abstract argumentation introduced by Dung in 1995 has shifted the focus from the internal structure of arguments to relations among arguments, and temporal dynamics for abstract argumentation was proposed by Barringer, Gabbay and Woods in 2005. In this tradition, we see arguments as reasoning processes, and the interaction among them as a coordination process.We argue that abstract argumentation can adopt ideas and techniques from formal theories of coordination, and as an example we propose a model of sequential abstract argumentation loosely inspired by Reo’s model of exogenous coordination. We show how the argumentation model can represent the temporal dynamics of the liar paradox and predator-prey like behaviour

UTRAN Traffic Parameters Estimation

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