Prevalence and Associated Factors of Hypertension Among Civil Servants Working in Arba Minch Town, South Ethiopia

Despite Hypertension is a global public health challenge and a leading modifiable risk factor for cardiovascular disease and death attention was not given in developing countries. Therefore measuring the prevalence and identifying predictors of Hypertension is very important. Institution based cross sectional study design was employed from March–April, 2016 by taking 319 randomly selected civil servants working in in Arba Minch town. Data was collected using structured questionnaire and standardized instruments for physical examination by 5 trained nurses. SPSS version 20 was used for data analysis. Bi-variable and Multivariate logistic regression was employed for analysis of risk factors. The mean SBP and DBP of study participants were 120.87 + 14.15 mmHg and 80.28 + 8.8 mmHg, respectively. The prevalence of hypertension was found to be 27.8% (95% CI = 22.9-32.7%). Civil servants of age 50 years and above [AOR = 13.3], age 40-49 years [AOR = 5], age 30-39 years [AOR = 3.5], abdominal obesity [AOR=12.2], general obesity [AOR = 4.2], stress status [AOR = 12.3], current alcohol drink [AOR = 3.3], ex-drinker [AOR = 8.9] and family history of hypertension [AOR = 5.6] were found to be significantly associated with hypertension. The prevalence indicates that it is hidden epidemic in this population; therefore for screening and risk reduction program are needed

Incidence of Opportunistic Infections Among Adult HIV Positive People Receiving Co-trimoxazole Prophylaxis

In Ethiopia, Co-trimoxazole prophylaxis therapy (CPT) used to prevent opportunistic infections among people living with HIV is the standard of practice; however incidence of opportunistic infection and their predictors are rarely documented in the country. This was a retrospective follow up study to describe the incidence and predictors of opportunistic infections among 244 adults receiving CPT. Participants were followed for a median time of 72 weeks. During a study period a total of 53opportunistic infections were recorded; making the overall incidence rate 23.9/100 person-years. High incidence of opportunistic infections is likely to occur if: the clients were married (adjusted hazard ratio (AHR) 1.965;(95% CI: 1.109, 3.451), had history of tuberculosis treatment (AHR: 2.34(95% CI:1.05, 5.24)), patients who are indicated for CPT because of both clinical and WHO clinical staging criteria(AHR 2.418 (95% CI:1.02, 5.72 ),and had poor adherence to CPT (AHR, 2.11 (95% CI: 1.19-3.72)). Eventhough adherence is non-substitutable strategy to prevent opportunistic infection, the cohort of HIV patients failed to adhere to CPT, which in turn resulthigh incidence of opportunistic infections among them, therefore improving adherence as guideline should be a priority to prevent OIs among people living with HIV in the study region

Performance of organically grown tomato cultivars under greenhouse conditions

A agricultura orgânica no Brasil cresce a taxas superiores a 30% ao ano, devido principalmente à maior conscientização dos consumidores que buscam alimentos saudáveis, livres de resíduos químicos e biológicos. Dentre as hortaliças cultivadas em sistema orgânico, o tomate constitui grande desafio para os produtores devido à inexistência de recomendações de manejo cultural e de cultivares desenvolvidas específicas para esse sistema de cultivo. Diante disso, o presente trabalho teve como objetivo avaliar o desempenho de cultivares de tomate sob sistema orgânico, em ambiente protegido. O experimento foi conduzido de maio a outubro de 2004 em campo, no município de Araraquara-SP. O delineamento experimental adotado foi blocos ao acaso, com quatro repetições e oito tratamentos (cultivares Avalon, Colibri, HTX-5415, HTX-8027, Sahel, San Marzano, San Vito e Jane). As plantas foram conduzidas em fileiras duplas, com duas hastes por planta no espaçamento de 0,8 m entre linhas e 0,6 m entre plantas (cerca de 20.000 plantas ha-1), sem poda apical. O híbrido Sahel destacou-se com o melhor desempenho para rendimento comercial. A traça-do-tomateiro se revelou como fator limitante à produção de tomate em sistema orgânico, sendo responsável, em média, por 17% de danos nos frutos colhidos das oito cultivares que foram avaliadas.Organic agriculture in Brazil has been increasing about 30% per year over the last few years, since consumers are seeking for healthier foods, i.e. nutritious and free of pesticide residues. Among organically grown vegetable crops, tomato is an attractive economic opportunity for growers. However, the lack of information about management practices and adapted cultivars to organic production systems under protected cultivation are pointed out as important constraints that prevents this activity to expand. This work aimed at evaluating the performance of indeterminate tomato cultivars in organic management systems in unheated plastic greenhouse. In both experiments tomato plants were staked. Plant spacing was 1.5 m between rows and 0.35 m between plants. They were planted in double line and spaced 0.8 m between lines and 0.6 m between plants (about 20,000 plants ha-1). The experiment was set up in a randomized complete block design, with four replications and eight treatments (cultivars: Avalon, Colibri, HTX-5415, HTX-8027, Sahel, San Marzano, San Vito, and Jane). Sahel hybrid exhibited an outstanding performance for marketable yield under organic cultivation. Tomato pinworm (Tuta absoluta) was a serious limiting pest for organically grown tomatoes, responding for 17% of damage in the fruits harvested from the evaluated cultivars

Both ghrelin deletion and unacylated ghrelin overexpression preserve muscles in aging mice

Sarcopenia, the decline in muscle mass and functionality during aging, might arise from age-associated endocrine dysfunction. Ghrelin is a hormone circulating in both acylated (AG) and unacylated (UnAG) forms with antiatrophic activity on skeletal muscle. Here, we show that not only lifelong overexpression of UnAG (Tg) in mice, but also the deletion of ghrelin gene (Ghrl KO) attenuated the age-associated muscle atrophy and functionality decline, as well as systemic inflammation. Yet, the aging of Tg and Ghrl KO mice occurs with different dynamics: while old Tg mice seem to preserve the characteristics of young animals, Ghrl KO mice features deteriorate with aging. However, young Ghrl KO mice show more favorable traits compared to WT animals that result, on the whole, in better performances in aged Ghrl KO animals. Treatment with pharmacological doses of UnAG improved muscle performance in old mice without modifying the feeding behavior, body weight, and adipose tissue mass. The antiatrophic effect on muscle mass did not correlate with modifications of protein catabolism. However, UnAG treatment induced a strong shift towards oxidative metabolism in muscle. Altogether, these data confirmed and expanded some of the previously reported findings and advocate for the design of UnAG analogs to treat sarcopenia