1,149 research outputs found
A Computer-Aided Method to Expedite the Evaluation of Prognosis for Childhood Acute Lymphoblastic Leukemia
This study presented a fully-automated computer-aided method (scheme) to detect metaphase chromosomes depicted on microscopic digital images, count the total number of chromosomes in each metaphase cell, compute the DNA index, and correlate the results to the prognosis of childhood acute lymphoblastic leukemia (ALL). The computer scheme first uses image filtering, threshold, and labeling algorithms to segment and count the number of the suspicious “chromosome,” and then computes a feature vector for each “detected chromosome.” Based on these features, a knowledge-based classifier is used to eliminate those “non-chromosome” objects (i.e., inter-phase cells, stain debris, and other kinds of background noises). Due to the possible overlap of the chromosomes, a classification criterion was used to identify the overlapped chromosomes and adjust the initially counted number of the total chromosomes in each image. In this preliminary study with 60 testing images (depicting metaphase chromosome cells) acquired from three pediatric patients, the computer scheme generated results matched with the diagnostic results provided by the clinical cytogeneticists. The results demonstrated the feasibility or potential of using a computerized method to replace the tedious and the reader-dependent diagnostic methods commonly used in genetic laboratories to date.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Mode locking of vortex matter driven through mesoscopic channels
We investigated the driven dynamics of vortices confined to mesoscopic flow
channels by means of a dc-rf interference technique. The observed mode-locking
steps in the -curves provide detailed information on how the number of rows
and lattice structure in the channel change with magnetic field. Minima in flow
stress occur when an integer number of rows is moving coherently, while maxima
appear when incoherent motion of mixed and row configurations is
predominant. Simulations show that the enhanced pinning at mismatch originates
from quasi-static fault zones with misoriented edge dislocations induced by
disorder in the channel edges.Comment: some minor changes were made, 4 pages, 4 figures, accepted for
publication in Phys. Rev. Let
Oxygen pressure-tuned epitaxy and optoelectronic properties of laser-deposited ZnO films on sapphire
Mode-locking in ac-driven vortex lattices with random pinning
We find mode-locking steps in simulated current-voltage characteristics of
ac-driven vortex lattices with {\it random} pinning. For low frequencies there
is mode-locking above a finite ac force amplitude, while for large frequencies
there is mode-locking for any small ac force. This is correlated with the
nature of temporal order in the different regimes in the absence of ac drive.
The mode-locked state is a frozen solid pinned in the moving reference of
frame, and the depinning from the step shows plastic flow and hysteresis.Comment: 4 pages, 4 figure
Phase-Locking of Vortex Lattices Interacting with Periodic Pinning
We examine Shapiro steps for vortex lattices interacting with periodic
pinning arrays driven by AC and DC currents. The vortex flow occurs by the
motion of the interstitial vortices through the periodic potential generated by
the vortices that remain pinned at the pinning sites. Shapiro steps are
observed for fields B_{\phi} < B < 2.25B_{\phi} with the most pronouced steps
occuring for fields where the interstitial vortex lattice has a high degree of
symmetry. The widths of the phase-locked current steps as a function of the
magnitude of the AC driving are found to follow a Bessel function in agreement
with theory.Comment: 5 pages 5 postscript figure
Structure and Magnetization of Two-Dimensional Vortex Arrays in the Presence of Periodic Pinning
Ground-state properties of a two-dimensional system of superconducting
vortices in the presence of a periodic array of strong pinning centers are
studied analytically and numerically. The ground states of the vortex system at
different filling ratios are found using a simple geometric argument under the
assumption that the penetration depth is much smaller than the spacing of the
pin lattice. The results of this calculation are confirmed by numerical studies
in which simulated annealing is used to locate the ground states of the vortex
system. The zero-temperature equilibrium magnetization as a function of the
applied field is obtained by numerically calculating the energy of the ground
state for a large number of closely spaced filling ratios. The results show
interesting commensurability effects such as plateaus in the B-H diagram at
simple fractional filling ratios.Comment: 12 pages, 19 figures, submitted for publicatio
Mode-locking in driven vortex lattices with transverse ac-drive and random pinning
We find mode-locking steps in simulated current-voltage characteristics of
driven vortex lattices with {\it random} pinning when an applied ac-current is
{\it perpendicular} to the dc-current. For low frequencies there is
mode-locking only above a non-zero threshold ac force amplitude, while for
large frequencies there is mode-locking for any small ac force. This is
consistent with the nature of {\it transverse} temporal order in the different
regimes in the absence of an applied ac-drive. For large frequencies the
magnitude of the fundamental mode-locked step depends linearly with the ac
force amplitude.Comment: 4 pages, 4 figures, .tar.gz fil
Dynamical Phases of Driven Vortices Interacting with Periodic Pinning
The finite temperature dynamical phases of vortices in films driven by a
uniform force and interacting with the periodic pinning potential of a square
lattice of columnar defects are investigated by Langevin dynamics simulations
of a London model. Vortices driven along the [0,1] direction and at densities
for which there are more vortices than columnar defects () are
considered. At low temperatures, two new dynamical phases, elastic flow and
plastic flow, and a sharp transition between them are identified and
characterized according to the behavior of the vortex spatial order, velocity
distribution and frequency-dependent velocity correlationComment: 4 pages with 4 figures. To be published in Phys. Rev. B Rapid
Communication
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