7 research outputs found
Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC)
Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes
Functional and evolutionary insights from the genomes of three parasitoid Nasonia species
Conformational Changes in the Lower Palm Domain of ASIC1a Contribute to Desensitization and RFamide Modulation
Functional and evolutionary insights from the genomes of three Parasitoid nasonia species
We report here genome sequences and comparative analyses of three closely related parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. tongicomis. Parasitoids are important regulators of arthropod populations, including major agricultural pests and disease vectors, and Nasonia is an emerging genetic model, particularly for evolutionary and developmental genetics. Key findings include the identification of a functional DNA methylation tool kit; hymenopteran-spedfic genes including diverse venoms; lateral gene transfers among Pox viruses, Wolbachia, and Nasonia; and the rapid evolution of genes involved in nuclearmitochondrial interactions that are implicated in spedation. Newly developed genome resources advance Nasonia for genetic research, accelerate mapping and cloning of quantitative trait loci, and will ultimately provide tools and knowledge for further increasing the utility of parasitoids as pest insect-control agents