Pengaruh Kualitas Pelayanan Terhadap Kepuasan Dan Loyalitas Mahasiswa (Studi Pada Mahasiswa Strata I Fakultas Ilmu Sosial Dan Ilmu Politikuniversitas Merdeka Malang)

Penelitan ini dilatarbelakangi oleh perkembangan dunia bisnis saat ini telah banyak kita temui suatu Perusahaan yang telah memasuki dunia pasar jasa. Hal itulah yang membuat suatu Perusahaan berlomba-lomba menawarkan kualitas pelayanan yang bera-gam dan terbaik.Tujuan dilakukan penelitian ini adalah untuk mengetahui seberapa besar pengaruh variabel kualitas pelayanan dalam mempengaruhi kepuasan dan loyalitas maha-siswa. Populasi dalam penelitian ini adalah mahasiswa Universitas Merdeka Malang Fakul-tas Ilmu Sosial Ilmu Politik sebanyak 207 responden dengan menggunakan teknik Slovin. Metode dalam penelitian ini adalah deskriptif kuantitatif. Data yang telah meme-nuhi uji validitas dan reliabilitas, maka melalui analisis Path.Penelitian ini menggunakan metode deskriptif kuantitatif. Hasil dari penelitian ini adalah kualitas pelayanan berpe-ngaruh signifikan terhadap loyalitas. Kualitas pelayanan berpengaruh signifikan terhadap kepu-asan dan kepuasan berpengaruh signifikan terhadap loyalitas

Thiol modified mycolic acids

Patient serum antibodies to mycolic acids have the potential to be surrogate markers of active tuberculosis (TB) when they can be distinguished from the ubiquitously present cross-reactive antibodies to cholesterol. Mycolic acids are known to interact more strongly with antibodies present in the serum of patients with active TB than in patients with latent TB or no TB. Examples of single stereoisomers of mycolic acids with chain lengths corresponding to major homologues of those present in Mycobacterium tuberculosis have now been synthesised with a sulfur substituent on the terminal position of the -chain; initial studies have established that one of these binds to a gold electrode surface, offering the potential to develop second generation sensors for diagnostic patient antibody detection.MMS and ADS wish to acknowledge support from the Government of Iraq through the award of PhD studentships.http://www.elsevier.com/locate/chemphysliphb2017BiochemistryChemistr

The presence of JAK2V617F in primary myelofibrosis or its allele burden in polycythemia vera predicts chemosensitivity to hydroxyurea

JAK2V617F-positive patients with essential thrombocythemia, as opposed to their mutation-negative counterparts, require lower doses of hydroxyurea (HU) for control of their platelet count. In the current study, we looked for predictors of HU response in 69 patients with primary myelofibrosis (PMF) and 56 with polycythemia vera (PV). JAK2V617F analysis was performed on bone marrow-derived DNA obtained at or near the time of diagnosis. HU response in PMF was associated with a shorter disease duration (P = 0.008), absence of previous therapy (P = 0.01), older age at diagnosis (P = 0.009), and presence of JAK2V617F (P = 0.02). On multivariable analysis, only the latter retained its significance (48% vs. 8% response in mutation positive vs. negative cases). In PV, JAK2V617F allele burden correlated directly with HU response (P = 0.05) and inversely with daily HU dose in responding patients (P = 0.02). The current study suggests that JAK2V617F presence identifies PMF patients who are likely to respond to HU therapy, and information on its allele burden helps in assigning the optimal starting dose in individual patients with PV