878 research outputs found
A General Model of Information Sharing in Oligopoly
Under which circumstances do oligopolists have an incentive to share private information about a stochastic demand or stochastic costs? We present a general model which includes virtually all models of the existing literature on information sharing as special cases. The analysis reveals that in contrast to the apparent inconclusivenss of previous results some simple principles determining the incentives to share information can be obtained. Most existing results are generalized and some interpretations are corrected, leading to a single general theory of the topic.Oligopoly, information sharing, stochastic demand, stochastic costs.
Product Differentiation, Uncertainty and the Stability of Collusion
The conventional view that product heterogeneity limits the scope for collusion among oligolpolists has been challenged in recent theoretical work. This paper provides an argument in support of the conventional view by emphasising the role of uncertainty. I introduce the idea that, with stochastic demand, an increase in the heterogeneity of products also leads to a decrease in the correlation of the firms? demand shocks. With imperfect monitoring, this makes collusion more difficult to sustain, as discriminating between random demand shocks and marginal deviations from the cartel strategy becomes more difficult. These effects are illustrated within a Hotelling-type duopoly model.Collusion, product differentiation, imperfect monitoring
Morphological Studies of the Immune Response to Vasectomy
1. The morphological changes in the epididymis, testes, and spleen, were studied at seven postoperative periods (6 wks and 4, 6, 9, 12, 15, and 18 mos.) after unilateral (left) vasectomy or sham operation, in a series of 72 mature Albino rats
Theory of Spin Relaxation in Two-Electron Lateral Coupled Si/SiGe Quantum Dots
Highly accurate numerical results of phonon-induced two-electron spin
relaxation in silicon double quantum dots are presented. The relaxation,
enabled by spin-orbit coupling and the nuclei of Si (natural or purified
abundance), are investigated for experimentally relevant parameters, the
interdot coupling, the magnetic field magnitude and orientation, and the
detuning. We calculate relaxation rates for zero and finite temperatures (100
mK), concluding that our findings for zero temperature remain qualitatively
valid also for 100 mK. We confirm the same anisotropic switch of the axis of
prolonged spin lifetime with varying detuning as recently predicted in GaAs.
Conditions for possibly hyperfine-dominated relaxation are much more stringent
in Si than in GaAs. For experimentally relevant regimes, the spin-orbit
coupling, although weak, is the dominant contribution, yielding anisotropic
relaxation rates of at least two order of magnitude lower than in GaAs.Comment: 11 pages, 10 figure
Equine recurrent uveitis - A spontaneous horse model of uveitis
Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis. We already identified and characterized novel autoantigens (malate dehydrogenase, recoverin, CRALBP) by analyzing the autoantibody-binding pattern of horses affected by spontaneous recurrent uveitis (ERU) to the retinal proteome. CRALBP also seems to be relevant to human autoimmune uveitis. Proteomic screening of vitreous and retinal samples from ERU diseased cases in comparison to healthy controls has led to the identification of a series of differentially regulated proteins, which are functionally linked to the immune system and the maintenance of the blood-retinal barrier. Copyright (c) 2008 S. Karger AG, Basel
Autologous point‐of‐care stromal vascular fraction transplantation in dogs with advanced osteoarthritis of the knee and hip joints
Objective
The aim of the study was to assess lameness in dogs with advanced osteoarthritis of the hip and knee joints after a single autologous point-of-care transplantation of the Stromal Vascular Fraction (SVF) into the affected joint.
Materials and methods
During a minilaparotomy, 10 g of falciform fat was removed from each patient for each joint to be treated. A modern and time-saving procedure (ARC TM System, InGeneron GmbH, Houston, USA) was used for the in-house preparation of the SVF, so that the isolated cells could be applied to the respective joint within 2 h after fat removal. In total, five knee joints of five patients and seven hip joints of four patients were treated.
Results
Improvement in lameness according to owner questionnaires was seen in 3 of 5 patients with knee joint arthritis and 2 of 4 patients with hip joint arthritis. Based on gait analysis, only one dog with gonarthrosis and one dog with coxarthrosis showed improvement up to a maximum of 3 months after surgery.
Conclusion
This is the first case series on the treatment of osteoarthrosis of the knee or hip joint using point-of-care transplantation of the SVF. In individual cases, this method may represent a therapeutic approach for the treatment in dogs with advanced cox- or gonarthrosis, although only a short-term effect can be expected, which calls into question the effort and costs involved
Amnion cells engineering: A new perspective in fetal membrane healing after intrauterine surgery?
In this study we aimed to set up an in vitro culture of the rabbit amnion in order to support in vivo fetal membrane healing capacity following fetoscopy. Fetal membranes were collected from a mid- gestational rabbit, and cultured on collagen support material for 14 days. 34 rabbits at 22 - 23 days gestational age ( GA) underwent fetoscopy. The entry site was randomly allocated to 4 closure technique study groups: group I, human amnion membrane ( n = 23); group II, collagen foil ( n = 16); group III, collagen plug ( n = 19), and group IV, collagen plug with cultured amnion cells ( n = 19). In all groups membrane access sites were additionally sealed with fibrin sealant, and the myometrium was closed with sutures. Fetal survival, amnion membrane integrity, and the presence of amniotic fluid were evaluated at 30 days GA. Cultures showed good survival in the collagen support material. Increased cellularity, survival and proliferations were observed. The amnion at the access site resealed in 58 - 64% of cases in groups II - IV, but none of the tested techniques was significantly better than the other. Histological examination indirectly revealed the anatomic repair of the membranes, since no entrapment of the membranes could be demonstrated in the myometrial wound. Copyright (c) 2006 S. Karger AG, Basel
Metamorphic conditions in the Nilgiri Granulite Terrane and the adjacent Moyar and Bhavani Shear Zones: A reevaluation
Data were presented on pressure and temperature determinations from the Nilgiri Hills. About 70 samples were analyzed by probe and several calibrations of garnet-pyroxene thermometry and barometry applied. Most calibrations gave considerable scatter; however, a new calibration by Bhattacharya, Raith, Lal, and others, accounting for nonideality in both garnet and orthopyroxene, gave consistent results of 754 + or - 52 C and 9.2 + or - 0.7 kbar. On the regional scale, a pressure increase of 6.5 to 7 kbar in the SW to 11 kbar in the NE was related to block tilting. A continuous pressure gradient into the Moyar shear zone suggests that the zone is not a suture juxtaposing unrelated blocks
A multiobjective optimization approach to compute the efficient frontier in data envelopment analysis
Data envelopment analysis is a linear programming-based operations research technique for performance measurement of decision-making units. In this paper, we investigate data envelopment analysis from a multiobjective point of view to compute both the efficient extreme points and the efficient facets of the technology set simultaneously. We introduce a dual multiobjective linear programming formulation of data envelopment analysis in terms of input and output prices and propose a procedure based on objective space algorithms for multiobjective linear programmes to compute the efficient frontier. We show that using our algorithm, the efficient extreme points and facets of the technology set can be computed without solving any optimization problems. We conduct computational experiments to demonstrate that the algorithm can compute the efficient frontier within seconds to a few minutes of computation time for real-world data envelopment analysis instances. For large-scale artificial data sets, our algorithm is faster than computing the efficiency scores of all decision-making units via linear programming
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