NAFTA Does Not Matter as Much as You Think (But Renegotiation Matters a Lot)

Most analysis of NAFTA begins by citing the huge increase in bilateral trade between the U.S., Canada and Mexico since 1993. U.S.-Mexico trade—exports plus imports—has grown three and a half times faster than U.S. GDP since NAFTA began in 1994. If NAFTA were solely responsible for that trade, renegotiating it on more favorable terms might have big payoffs. However, there are seven problems with thinking NAFTA has mattered or can matter very much

Polaron relaxation in ferroelectric thin films

We report a dielectric relaxation in ferroelectric thin films of the ABO3 family. We have compared films of different compositions with several growth modes: sputtering (with and without magnetron) and sol-gel. The relaxation was observed at cryogenic temperature (T<100K) for frequencies from 100Hz up to 10MHz. This relaxation activation energy is always lower than 200meV. It is very similar to the polaron relaxation that we reported in the parent bulk perovskites. Being independent of the materials size, morphology and texture, this relaxation can be a useful probe of defects in actual integrated capacitors with no need for specific shapin

Was NAFTA Good for the United States?

NAFTA has neither been the enormous success that its supporters believe, nor the disaster that its detractors claim. Renegotiating NAFTA — or even threatening to repeal it — is not a high-stakes proposition. The treaty simply does not possess the leverage to deliver a major boost or setback to the U.S. manufacturing sector

Co‐existing monophasic teratoma and uterine adenocarcinoma in a female dog

Ovarian teratomas are occasionally reported in dogs; the rarest type is the monophasic teratoma,composed of tissues originating from only one germ layer. Canine endometrial adenocarcinomas are also rare in dogs and mainly affect geriatric females. This report describes case of co-existing ovarian teratoma and uterine adenocarcinoma in a 10-year old nulliparous female Boxer presented with lethargy, anorexia and purulent vaginal discharge. Abdominal ultrasonography evidenced pyometra and a mass in the left ovary. This was composed of a uniform whitish tissue with multiple cystic structures. The histology revealed an atrophy of the ovarian parenchyma, compressed by a proliferation of well-differentiated nervous tissue staining positively to vimentin, S100 and neuronal specific enolase (NSE), and negatively to keratin and inhibin. The left uterine horn, whose diameter was markedly increased, showed foci of endometrial cellular atypia, evident nucleoli and mitoses, at light microscopy. To our best knowledge, this is the first report of a coexisting ovarian monophasic teratoma and endometrial adenocarcinoma, two rare reproductive neoplasia in dogs

A Ranking Method Based on Common Weights and Benchmark Point

The highest efficiency score 1 (100% efficiency) is regarded as a common benchmark for Decision Making Units (DMUs). This brings about the existence of more than one DMU with the highest score. Such a case normally occurs in all Data Envelopment Analysis (DEA) models and also in all the Common Set of Weights (CSWs) methods and it may lead to the lack of thorough ranking of DMUs. And ideal DMU based on its specific structure is a unit that no unit would do better than. Therefore, it can be utilized as a benchmark for other units. We are going to take advantage of this feature to introduce a linear programming problem that will produce CSWs. The proposed method assures that the efficiency of all the units is less than that of the benchmark unit. As a result, it provides a comprehensive ranking of DMUs. Moreover, the proposed method is also noteworthy regarding computation. A numerical example is suggested to clarify and explain the proposed method and compare it to two other CSWs methods. Finally, 33 universities in Iran were ranked and compared using the proposed method

Conception and evaluation of a 3D musculoskeletal finite element foot model.

International audienceThis paper introduces a new patient-specific musculoskeletal and Finite Element (FE) model of the foot aimed to be used in the context of deep pressure ulcer prevention, orthopedic and motion analysis. This model is evaluated in both static and dynamic frameworks

Immunohistochemical Evaluation of TNF Expression in Canine Cystic Endometrial Hyperplasia

Tumour Necrosis Factor (TNF) has been identified in the uterus of several species, and altered TNF expression is reported in some pathological conditions. This study sought to evaluate TNF expression in canine cystic endometrial hyperplasia (CEH; n=20) and compare it with expression in postpartum samples (PP; n=5).This work was supported by Portuguese Foundation for Science and Technology, Center for Studies in Education, Technologies and by Health and by strategic project PEst-OE/CED/UI4016/201

Analyse des mutations des domaines ISDR et V3 de la protéine NS5A du virus de l&#039;hépatite C avant le traitement par l&#039;interféron avec ou sans ribavirine

Aim of the study. – The hepatitis C virus (HCV) non-structural NS5A protein has been controversially implicated in the resistance of HCV to interferon therapy in clinical studies. In Japan, mutations in the interferon sensitivity-determining region (ISDR) in the NS5A gene were associated with response to interferon therapy in patients infected with genotype 1b. In contrast, studies from Europe did not confirm such association. More recently, it has been suggested that the V3 domain outside the putative ISDR might also have amino acids changes that may be involved in the resistance to IFN. In this study, the relationship between NS5A mutations in ISDR and V3 domains and virological response to therapy were investigated. Materials and methods. – The NS5A gene was sequenced from 35 HCV genotype 1b infected patients at D0 of a prospective clinical trial of interferon therapy and interferon plus Ribavirin combination therapy. Results. – In the ISDR domain, we did not observe any significant differences in amino acids changes between responders (1.7 ± 1.8, n = 19, range 0–6) and non-responders (1.1 ± 0.8, n = 14, range: 0–3), (P = 0.483), to therapy before the beginning of treatment. In the V3 domain, we found more mutations in responders (6.5 ± 1.9, range: 2–11) than in non-responders (4.7 ± 1.2, range: 3–8) (P = 0.0013), before the beginning of treatment. Conclusion. – Our results confirm that, in Europe, the ISDR domain is not predictive for treatment success but suggest that the V3 domain have greater variability in responders than non-responders