Search for AGN counterparts of unidentified Fermi-LAT sources with optical polarimetry: Demonstration of the technique

The third Fermi-LAT catalog (3FGL) presented the data of the first four years of observations from the Fermi Gamma-ray Space Telescope mission. There are 3034 sources, 1010 of which still remain unidentified. Identifying and classifying gamma-ray emitters is of high significance with regard to studying high-energy astrophysics. We demonstrate that optical polarimetry can be an advantageous and practical tool in the hunt for counterparts of the unidentified gamma-ray sources (UGSs). Using data from the RoboPol project, we validated that a significant fraction of active galactic nuclei (AGN) associated with 3FGL sources can be identified due to their high optical polarization exceeding that of the field stars. We performed an optical polarimetric survey within $3\sigma$ uncertainties of four unidentified 3FGL sources. We discovered a previously unknown extragalactic object within the positional uncertainty of 3FGL J0221.2+2518. We obtained its spectrum and measured a redshift of $z=0.0609\pm0.0004$. Using these measurements and archival data we demonstrate that this source is a candidate counterpart for 3FGL J0221.2+2518 and most probably is a composite object: a star-forming galaxy accompanied by AGN. We conclude that polarimetry can be a powerful asset in the search for AGN candidate counterparts for unidentified Fermi sources. Future extensive polarimetric surveys at high galactic latitudes (e.g., PASIPHAE) will allow the association of a significant fraction of currently unidentified gamma-ray sources.Comment: accepted to A&

RoboPol: Connection between optical polarization plane rotations and gamma-ray flares in blazars

We use results of our 3 year polarimetric monitoring program to investigate the previously suggested connection between rotations of the polarization plane in the optical emission of blazars and their gamma-ray flares in the GeV band. The homogeneous set of 40 rotation events in 24 sources detected by {\em RoboPol} is analysed together with the gamma-ray data provided by {\em Fermi}-LAT. We confirm that polarization plane rotations are indeed related to the closest gamma-ray flares in blazars and the time lags between these events are consistent with zero. Amplitudes of the rotations are anticorrelated with amplitudes of the gamma-ray flares. This is presumably caused by higher relativistic boosting (higher Doppler factors) in blazars that exhibit smaller amplitude polarization plane rotations. Moreover, the time scales of rotations and flares are marginally correlated.Comment: 12 pages, 16 figures, accepted to MNRA

Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.

Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson's disease (PD), multiple system atrophy, and dementia with Lewy bodies. Therefore, examination of compounds that abolish the process of seeding is considered a key step towards therapy of several synucleinopathies. Using biophysical, biochemical and cell-culture-based assays, assessment of eleven compounds, extracted from Chinese medicinal herbs, was performed in this study for their effect on α-syn fibril formation and toxicity caused by the seeding process. Salvianolic acid B and dihydromyricetin were the two compounds that strongly inhibited the fibril growth and neurotoxicity of α-syn. In an in-vitro cell model, these compounds decreased the insoluble phosphorylated α-syn and aggregation. Also, in primary neuronal cells, these compounds showed a reduction in α-syn aggregates. Both compounds inhibited the seeded fibril growth with dihydromyricetin having the ability to disaggregate preformed α-syn fibrils. In order to investigate the inhibitory mechanisms of these two compounds towards fibril formation, we demonstrated that salvianolic acid B binds predominantly to monomers, while dihydromyricetin binds to oligomeric species and to a lower extent to monomers. Remarkably, these two compounds stabilized the soluble non-toxic oligomers lacking β-sheet content after subjecting them to proteinase K digestion. Eleven compounds were tested but only two showed inhibition of α-syn aggregation, seeded fibril formation and toxicity in vitro. These findings highlight an essential beginning for development of new molecules in the field of synucleinopathies treatment.The work conducted by Dr. El-Agnaf laboratory was supported by Qatar Biomedical Research Institute under the Start-up Fund SF 2017–007. Funding for this work was provided in part by NIH/NIA grant R37AG019391 to D.E. This study was made possible by NPRP grant 4–1371–1-223 from the Qatar National Research Fund (a member of Qatar Foundation). The funding bodies provided financial support for this study; they had no role in the study design, performance, data collection and analysis, decision to publish and preparation/writing of the manuscript

RoboPol: the optical polarization of gamma-ray-loud and gamma-ray-quiet blazars

We present average R-band optopolarimetric data, as well as variability parameters, from the first and second RoboPol observing season. We investigate whether gamma-ray-loud and gamma-ray-quiet blazars exhibit systematic differences in their optical polarization properties. We find that gamma-ray-loud blazars have a systematically higher polarization fraction (0.092) than gamma-ray-quiet blazars (0.031), with the hypothesis of the two samples being drawn from the same distribution of polarization fractions being rejected at the 3σ level. We have not found any evidence that this discrepancy is related to differences in the redshift distribution, rest-frame R-band luminosity density, or the source classification. The median polarization fraction versus synchrotron-peak-frequency plot shows an envelope implying that high-synchrotron-peaked sources have a smaller range of median polarization fractions concentrated around lower values. Our gamma-ray-quiet sources show similar median polarization fractions although they are all low-synchrotron-peaked. We also find that the randomness of the polarization angle depends on the synchrotron peak frequency. For high-synchrotron-peaked sources, it tends to concentrate around preferred directions while for low-synchrotron-peaked sources, it is more variable and less likely to have a preferred direction. We propose a scenario which mediates efficient particle acceleration in shocks and increases the helical B-field component immediately downstream of the shock

Search for AGN counterparts of unidentified Fermi-LAT sources with optical polarimetry Demonstration of the technique

Context. The third Fermi-LAT catalog (3FGL) presented the data of the first four years of observations from the Fermi Gamma-ray Space Telescope mission. There are 3034 sources, 1010 of which still remain unidentified. Identifying and classifying gamma-ray emitters is of high significance with regard to studying high-energy astrophysics.Aims. We demonstrate that optical polarimetry can be an advantageous and practical tool in the hunt for counterparts of the unidentified gamma-ray sources (UGSs).Methods. Using data from the RoboPol project, we validated that a significant fraction of active galactic nuclei (AGN) associated with 3FGL sources can be identified due to their high optical polarization exceeding that of the field stars. We performed an optical polarimetric survey within 3 sigma uncertainties of four unidentified 3FGL sources.Results. We discovered a previously unknown extragalactic object within the positional uncertainty of 3FGL J0221.2 + 2518. We obtained its spectrum and measured a redshift of z = 0.0609 +/- 0.0004. Using these measurements and archival data we demonstrate that this source is a candidate counterpart for 3FGL J0221.2 + 2518 and most probably is a composite object: a star-forming galaxy accompanied by AGN.Conclusions. We conclude that polarimetry can be a powerful asset in the search for AGN candidate counterparts for unidentified Fermi sources. Future extensive polarimetric surveys at high Galactic latitudes (e.g., PASIPHAE) will allow the association of a significant fraction of currently unidentified gamma-ray sources

Search for AGN counterparts of unidentified Fermi-LAT sources with optical polarimetry: Demonstration of the technique

Context. The third Fermi-LAT catalog (3FGL) presented the data of the first four years of observations from the Fermi Gamma-ray Space Telescope mission. There are 3034 sources, 1010 of which still remain unidentified. Identifying and classifying γ-ray emitters is of high significance with regard to studying high-energy astrophysics. Aims. We demonstrate that optical polarimetry can be an advantageous and practical tool in the hunt for counterparts of the unidentified γ-ray sources (UGSs). Methods. Using data from the RoboPol project, we validated that a significant fraction of active galactic nuclei (AGN) associated with 3FGL sources can be identified due to their high optical polarization exceeding that of the field stars. We performed an optical polarimetric survey within 3σ uncertainties of four unidentified 3FGL sources. Results. We discovered a previously unknown extragalactic object within the positional uncertainty of 3FGL J0221.2+2518. We obtained its spectrum and measured a redshift of z = 0.0609 ± 0.0004. Using these measurements and archival data we demonstrate that this source is a candidate counterpart for 3FGL J0221.2+2518 and most probably is a composite object: a star-forming galaxy accompanied by AGN. Conclusions. We conclude that polarimetry can be a powerful asset in the search for AGN candidate counterparts for unidentified Fermi sources. Future extensive polarimetric surveys at high Galactic latitudes (e.g., PASIPHAE) will allow the association of a significant fraction of currently unidentified γ-ray sources