The high-frequency backscattering angular response of gassy sediments: Model/data comparison from the Eel River Margin, California

A model for the high-frequency backscatter angular response of gassy sediments is proposed. For the interface backscatter contribution we adopted the model developed by Jackson et al. @J. Acoust. Soc. Am. 79, 1410–1422 ~1986!#, but added modifications to accommodate gas bubbles. The model parameters that are affected by gas content are the density ratio, the sound speed ratio, and the loss parameter. For the volume backscatter contribution we developed a model based on the presence and distribution of gas in the sediment. We treat the bubbles as individual discrete scatterers that sum to the total bubble contribution. This total bubble contribution is then added to the volume contribution of other scatters. The presence of gas affects both the interface and the volume contribution of the backscatter angular response in a complex way that is dependent on both grain size and water depth. The backscatter response of fine-grained gassy sediments is dominated by the volume contribution while that of coarser-grained gassy sediments is affected by both volume and interface contributions. In deep water the interface backscatter is only slightly affected by the presence of gas while the volume scattering is strongly affected. In shallow water the interface backscatter is severely reduced in the presence of gas while the volume backscatter is only slightly increased. Multibeam data acquired offshore northern California at 95 kHz provides raw measurements for the backscatter as a function of grazing angle. These raw backscatter measurements are then reduced to scattering strength for comparison with the results of the proposed model. The analysis of core samples at various locations provides local measurements of physical properties and gas content in the sediments that, when compared to the model, show general agreement

Canadian Speaker Session 10: Canada and U.S. Approaches to Cross-Border Sales of Pharmaceuticals - Canadian Speaker

cross-border sales of pharmaceuticals-Canada and United State

Information Dissemination Needs of Indonesian Migrant Domestic Workers in Malaysia

Substantial numbers of Indonesian women are seeking employment as domestic workers in Malaysia in order to escape poverty and unemployment and to be able to support their families back home. Most Indonesian domestic workers in Malaysia face unpleasant working conditions with long working hours and no freedom to move or communicate; some find themselves in a situation of abuse. In many cases, the decision to work abroad is made without being properly informed about what to expect. Furthermore, most of the Indonesian migrant domestic workers do not know about process and procedures and are not aware of their rights and the possibilities of seeking assistance when problems occur. In order to empower the target group, relevant information need to be disseminated. Current strategies do not seem to achieve the desired effect. Many of the affected women come from remote areas, are poor and have a low level of education; therefore, their skills to make use of written or even digital information are limited. Appropriate strategies are suggested to utilise traditional and commonly used information dissemination channels such as cultural performances, group discussions and radio. Educational measures should be combined with aspects of local entertainment culture in order to attract attention and to provoke identification with the issues discussed. Further research is necessary to actually develop an appropriate information dissemination strategy with regard to the target group and to evaluate its benefits by conducting pilot projects

The gastric acid pocket is attenuated in H. pylori infected subjects

Objective Gastric acid secretory capacity in different anatomical regions, including the postprandial acid pocket, was assessed in Helicobacter pylori positive and negative volunteers in a Western population. Design We studied 31 H. pylori positive and 28 H. pylori negative volunteers, matched for age, gender and body mass index. Jumbo biopsies were taken at 11 predetermined locations from the gastro-oesophageal junction and stomach. Combined high-resolution pH metry (12 sensors) and manometry (36 sensors) was performed for 20 min fasted and 90 min postprandially. The squamocolumnar junction was marked with radio-opaque clips and visualised radiologically. Biopsies were scored for inflammation and density of parietal, chief and G cells immunohistochemically. Results Under fasting conditions, the H. pylori positives had less intragastric acidity compared with negatives at all sensors >1.1 cm distal to the peak lower oesophageal sphincter (LES) pressure (p<0.01). Postprandially, intragastric acidity was less in H. pylori positives at sensors 2.2, 3.3 and 4.4 cm distal to the peak LES pressure (p<0.05), but there were no significant differences in more distal sensors. The postprandial acid pocket was thus attenuated in H. pylori positives. The H. pylori positives had a lower density of parietal and chief cells compared with H. pylori negatives in 10 of the 11 gastric locations (p<0.05). 17/31 of the H. pylori positives were CagA-seropositive and showed a more marked reduction in intragastric acidity and increased mucosal inflammation. Conclusions In population volunteers, H. pylori positives have reduced intragastric acidity which most markedly affects the postprandial acid pocket

Resistance training leads to large improvements in strength and moderate improvements in physical function in adults who are overweight or obese: a systematic review

QuestionsWhat are the effects of resistance training on muscle strength, physical function and muscle power in adults who are overweight or obese? Which factors moderate the effects?DesignSystematic review of randomised controlled trials, with random effects meta-analyses and meta-regressions.ParticipantsAdults who are overweight or obese.InterventionResistance training lasting ≥ 4 weeks.Outcome measuresMuscle strength, muscle power and physical function.ResultsThirty trials with 1,416 participants met the eligibility criteria. Pooled analyses indicated that resistance training has a large beneficial effect on muscle strength (SMD 1.39, 95% CI 1.05 to 1.73, I2 = 85%) and a moderate effect on physical function (SMD 0.67, 95% CI 0.25 to 1.08, I2 = 71%) in adults who are overweight or obese. However, the effect of resistance training on muscle power was unclear (SMD 0.42, 95% CI −3.3 to 4.2, I2 = 46%). The effect of resistance training on strength was greatest for the upper body (versus lower/whole body: β = 0.35, 95% CI 0.05 to 0.66) and in dynamic strength tests (versus isometric/isokinetic: β = 1.20, 95% CI 0.60 to 1.81), although trials judged to have good methodological quality reported statistically smaller effects (versus poor/fair quality: β = −1.21, 95% CI −2.35 to −0.07). Concomitant calorie restriction did not modify strength gains but reduced the effect of resistance training on physical function (β = −0.79, 95% CI −1.41 to −0.17). Small study effects were evident for strength outcomes (β = 5.9, p < 0.001).ConclusionsResistance training has a large positive effect on muscle strength and a moderate effect on physical function in adults who are overweight or obese. However, the effect of resistance training on muscle power is uncertain. In addition, concomitant calorie restriction may compromise the functional adaptations to resistance training

Effect of home‐based resistance training performed with or without a high‐speed component in adults with severe obesity

1) To evaluate the effects of walking and home‐based resistance training on function, strength, power, anthropometry and quality of life (QoL) in adults with severe obesity, and 2) to assess whether performing resistance exercises with maximal concentric velocity provides additional benefits compared with traditional slow‐speed resistance training.MethodsAdults with a body mass index of ≥40 kg/m2 were randomised to slow‐speed strength training (ST; n = 19) or high‐speed power training (PT; n = 19). Both groups completed a walking intervention and home‐based resistance training (2x/week for 6‐months). The PT group performed resistance exercises with maximal intended concentric velocity, whereas the ST group maintained a slow (2‐s) concentric velocity.ResultsAt 6‐months, weight loss was ~3 kg in both groups. Both groups significantly improved function (gz = 1.04‐1.93), strength (gz = 0.65‐1.77), power (gz = 0.66‐0.85), contraction velocity (gz = 0.65‐1.12) and QoL (gz = 0.62‐1.54). Between‐group differences in shoulder press velocity (‐0.09 m·s‐1, gs = ‐0.95 [‐1.63, ‐0.28]) and six‐minute walk test (‐16.9 m, gs = ‐0.51 [‐1.16, 0.13]) favoured the PT group.ConclusionsHome‐based resistance training and walking leads to significant improvements in functional and psychological measures in adults with severe obesity. In addition, considering the between‐group effect sizes and their uncertainty, performing resistance exercises with maximal concentric speed is a simple adjustment to conventional resistance training that yields negligible negative effects but potentially large benefits on walking capacity and upper‐limb contraction velocity

Short-Term Training and Detraining Effects of Supervised vs. Unsupervised Resistance Exercise in Aging Adults

Orange, ST, Marshall, P, Madden, LA, and Vince, RV. Short-term training and detraining effects of supervised vs. unsupervised resistance exercise in aging adults. J Strength Cond Res 33(10): 2733-2742, 2019-This study compared the effects of a 4-week supervised (SUP) resistance training program and unsupervised (UNSUP) resistance training program followed by 12 weeks of detraining (DET). Thirty-six healthy aging adults (age: 53.6 ± 3.6 years; body mass index: 28.3 ± 5.1 kg·m) were randomly allocated to an SUP group (n = 17) or a UNSUP group (n = 19). Participants completed 3 training sessions per week using resistance bands and body weight movements. Measures of physical performance were administered at baseline, at the end of the training program, and after the DET period. Function was assessed with the 6-minute walk test (6MWT), timed up-and-go (TUG), 30-second chair sit-to-stand (STS), stair-climb test (SCT), 40-m fast-paced walk test (FPWT) and sit-and-reach test (SRT), whereas the isometric midthigh pull (IMTP) and hand grip test were used to measure muscle strength. After training, improvements in performance were found in the 6MWT, TUG, 30-second chair STS, SCT, FPWT, SRT, and IMTP (p ≤ 0.05), with no significant differences between groups (p > 0.05). In addition, most of the training-induced improvements remained significantly above baseline values after the DET period (p ≤ 0.05). No significant between-group differences were observed after training or DET (p > 0.05). Four weeks of either SUP or UNSUP resistance training is sufficient to substantially improve muscle strength and function in aging adults, and these gains are largely preserved after prescribed exercise cessation. Home-based resistance training seems to be a practical and effective alternative to traditional SUP programs that may help circumvent many barriers to physical activity in aging adults