Показатели липидного состава кожного барьера у новорожденных детей

Study results of neutral lipids of superficial hydro-lipid film (SHLF) in healthy newborns ( n = 46), in the children with severe allergic history ( n = 29), in newborns with toxic erythema ( n = 34) and nappies dermatitis ( n = 29) are presented in the article. The study is performed using thin-layer chromatography. Marked changes in lipid structure of dermal SHLF in all children in comparison with controls are revealed which needs further observation and correction.Представлены результаты исследования нейтральных липидов поверхностной гидролипидной пленки (ПГЛП) кожи у здоровых новорожденных ( n = 46), у детей с отягощенным аллергоанамнезом ( n = 29), у новорожденных с токсической эритемой ( n = 34) и пеленочным дерматитом ( n = 29), выполненного методом тонкослойной хроматографии. Выявлены значительные изменения в липидном составе ПГЛП кожи у обследуемых детей всех групп в сравнении с контролем, что требует дальнейшего наблюдения и своевременной коррекции

Networks of Emotion Concepts

The aim of this work was to study the similarity network and hierarchical clustering of Finnish emotion concepts. Native speakers of Finnish evaluated similarity between the 50 most frequently used Finnish words describing emotional experiences. We hypothesized that methods developed within network theory, such as identifying clusters and specific local network structures, can reveal structures that would be difficult to discover using traditional methods such as multidimensional scaling (MDS) and ordinary cluster analysis. The concepts divided into three main clusters, which can be described as negative, positive, and surprise. Negative and positive clusters divided further into meaningful sub-clusters, corresponding to those found in previous studies. Importantly, this method allowed the same concept to be a member in more than one cluster. Our results suggest that studying particular network structures that do not fit into a low-dimensional description can shed additional light on why subjects evaluate certain concepts as similar. To encourage the use of network methods in analyzing similarity data, we provide the analysis software for free use (http://www.becs.tkk.fi/similaritynets/)

“Folk History” of the Battle of Stalingrad (Based on the Materials of the Research Project “Stalingraders in the Battle of Stalingrad”)

In 2012–2013, a project of high social significance, novelty, and a scientific challenge was implemented in Volgograd. The goal of the project was to prepare the manuscript of a biographic encyclopedia “Stalingraders in The Battle of Stalingrad”. The database of sources that have never been published consists of materials of 80 museums and archives of Volgograd and 30 municipal subjects of the Volgograd region. The novelty of the project consists in the fact that it constitutes the first case of biographic and prosopographic research on the local aspect of the battle. The manuscript includes more than 5 000 biographic articles. The project bears high social significance since it generalizes the data on people for whom the Battle of Stalingrad was the battle for their “little Motherland”. Introducing the biographies of Stalingraders into the research has a memorial goal. The research problems under the project are also important. The new research paradigm, defined as “human dimension of war” leads to collecting a huge amount of empirical data. The idea of the project, as well as the difficulties in its completion, are very characteristic for the current stage of Russian research of the Great Patriotic War. Data collection, large-scale search projects on war cites, interest to all new resources go beyond the professional society of historians. However, generalizing this material, and verifying sources remains within the competence of experts. The historians must evaluate the conceptual idea of quantitative methods in studying war history of Russia. In the project, the quantitative methods lead to supported conclusions about close interaction of the front and the rear at the level of everyday life; they remove the stereotypes of exclusively sacrificial role of civilians in the Battle of Stalingrad. The project overcomes the one-sided look at the war generation as to the “chosen” one, having a special part in history; this allows the return to the historic justice in the space of memory. Description of the project work, analysis of problems and prospects of using prosopographic methods in the study of the Battle of Stalingrad are performed by E.V. Ogarkova. Collection of biographical articles, work with sources, selection of fragments of biographies of Stalingradians for publication in the article are performed by A.A. Ogarkov. General editing of the article is carried out by I.O. Tyumentsev

Tuning of Electronic and Vibrational Properties of Transition Metal Selenides TSe₂ (T = Os, Ru) and Their Metallization under High Pressure

We present a systematic analysis of electrical properties of two transition metal selenides OsSe2 and RuSe2 under conditions of low temperature down to 1.8K and external pressure up to 43 GPa. Both compounds have a pyrite-type crystal structure under ambient conditions and, according to Raman spectroscopy, do not undergo phase transitions up to the highest pressures. OsSe2 and RuSe2 undergo semiconductor-to-metal transitions at pressures up to 15 GPa. Further increase in pressure leads to the appearance of a superconducting transition at low temperatures. At 40 GPa, the critical temperatures of the superconducting transition reach maximum values of 5.5 and 6K for RuSe2 and OsSe2, respectively. © 2020, Pleiades Publishing, Inc

Distribution of Iron Atoms in Nonequivalent Crystallographic Sites of Fe7C3 Carbide in Core–Shell Nanostructures

International audienc

The Condorcet paradox revisited

We analyze the Condorcet paradox within a strategic bargaining model with majority voting, exogenous recognition probabilities, and no discounting. Stationary subgame perfect equilibria (SSPE) exist whenever the geometric mean of the players' risk coefficients, ratios of utility differences between alternatives, is at most one. SSPEs ensure agreement within finite expected time. For generic parameter values, SSPEs are unique and exclude Condorcet cycles. In an SSPE, at least two players propose their best alternative and at most one player proposes his middle alternative with positive probability. Players never reject best alternatives, may reject middle alternatives with positive probability, and reject worst alternatives. Recognition probabilities represent bargaining power and drive expected delay. Irrespective of utilities, no delay occurs for suitable distributions of bargaining power, whereas expected delay goes to infinity in the limit where one player holds all bargaining power. Contrary to the case with unanimous approval, a player benefits from an increase in his risk aversion

Sputnik Light and Sputnik V Vaccination Is Effective at Protecting Medical Personnel from COVID-19 during the Period of Delta Variant Dominance

Medical personnel are a group of people that often encounter infectious agents, leading to greater risk of contracting infectious diseases. Specific prevention of diseases in this group is a priority. The epidemiological effectiveness of COVID-19 prevention in the group of medical workers due to the emergence of new variants of concern of the SARS-CoV-2 virus has not been studied in sufficient depth. We conducted a study of the effectiveness of vaccine use to protect medical workers at a large medical center for obstetrics and gynecology in Moscow. Sputnik V and Sputnik Light were the main vaccines used for the prevention of COVID-19. The vaccines are based on a variant of the S-protein of the SARS-CoV-2 virus, with adenovirus serotypes 5 and 26 as the vector for delivery. Vaccination of employees occurred during the period in which the Delta variant was spreading. The overall epidemiological effectiveness was 81.7% (73.1–87.6%) during the period in which the Delta variant was dominant. During the period from the beginning of vaccination (26 November 2020) until 8 February 2022, the overall effectiveness was 89.1% (86.9–91.0%). As expected, the highest effectiveness during this period was obtained in the group that received the third and fourth doses—96.5% (75.0–99.5%). The severity of COVID-19 in the vaccinated group was significantly lower than in the unvaccinated group

Predictors of Acute Encephalopathy in Patients with COVID-19

Introduction: The majority of patients with severe COVID-19 suffer from delirium as the main sign of encephalopathy associated with this viral infection. The aim of this study was to identify early markers of the development of this condition. Materials: The prospective cohort-based study included patients with community-acquired pneumonia and confirmed pulmonary tissue infiltration based on CT data, with a lesion consisting of at least 25% of one lung. The main group included patients who have developed acute encephalopathy (10 patients, 3 (30%) women; average age, 47.9 ± 7.3 years). The control group included patients who at discharge did not have acute encephalopathy (20 patients, 11 (55%) women; average age, 51.0 ± 10.5 years). The study collected clinical examination data, comprehensive laboratory data, neurophysiological data, pulse oximetry and CT data to identify the predictors of acute encephalopathy (study ClinicalTrials.gov identifier NCT04405544). Results: Data analysis showed a significant relationship between encephalopathy with the degree of lung tissue damage, arterial hypertension, and type 2 diabetes mellitus, as well as with D-dimer, LDH, and lymphopenia. Conclusions: The development of encephalopathy is secondary to the severity of the patient’s condition since a more severe course of the coronavirus infection leads to hypoxic brain damage