Assessment the Knowledge of the New Trends in Obesity Treatment among Female Students of Applied Medical Sciences in Umm Al-Qura University-Makkah

Obesity is associated with numerous diseases and metabolic abnormalities. Treatment should begin with lifestyle changes that focus on behavioral modification, diet, and exercise. When lifestyle modification schemes are unsuccessful, drug therapy is an attractive option. Food and Drug Administration (FDA) regulates dietary supplements, including those promoted for weight loss. Weight-loss supplements differ from over-the-counter or prescription medications in that the FDA does not classify them as drugs. In this study we Assess the knowledge and beliefs of students in Faculty of Applied Medical Sciences about new methods used for weight reduction.  The present study was conducted on 70 interviewed of students. Specific questionnaire was used to collect data about methods used for weight control. Statistical analysis was performed by using SPSS software version 19. The obtained data showed that student’s preferred physical activity and diet they have awareness about detox water but little awareness about Conjugated linoleic acid  and blood group diet.  The present study suggested that Healthcare professionals must make efforts to educate themselves and public about new methods used for weight control. Keywords: Obesity, blood group diet, detoxes water and Conjugated linoleic acid

Potentiation of raloxifene cytotoxicity against MCF-7 breast cancer cell lines via transdermal delivery and loading on self-emulsifying nanoemulsions

Purpose: To enhance raloxifene (RLX) delivery and cytotoxicity against breast cancer (MCF-7) cell lines. Methods: This was a solubility study of RLX in different oils, surfactants, and co-surfactants. Twelve formulae were tested to reach the smallest  globular size, and hydroxypropyl methylcellulose, (HPMC), and Carbopol 947 polymers were tested for formation of transdermal films. The formula  with the lowest size was compared with raw RLX in diffusion studies using a Franz diffusion cell. Finally, a cytotoxicity study against MCF-7 breast cancer cell lines was conducted. Results: The maximum solubility of RLX was in Tween 80, peppermint oil, and PEG 200; therefore, these were the main components of the 12 formulations. The release of RLX loaded on the selfnanoemulsion drug delivery system (SNEDDS) was increased 3-fold compared with raw RLX.Cytotoxicity results revealed that RLX SNEDDs decreased MCF-7 cell survival by approximately 40 %, compared with raw RLX (control), which augmented the RLX suppression of breast cancer cell lines. Conclusion: Improvement in RLX cytotoxicity is a novel strategy to suppress breast cancer. Keywords: Raloxifene, Osteoporosis, Bioavailability, Nanoemulsion, Nanoparticle

Conductometric and volumetric study of copper sulphate in aqueous ethanol solutions at different temperatures

AbstractAn Anton Par Model 55 densimeter was used to measure the densities of copper sulphate solutions in H2O and EtOH–H2O at 298.15K, 303.15K, 308.15K, and 313.15K. The acquired information was used to ascertain the apparent molar volumes, limiting partial molar volumes, and transfer partial molar volumes of copper sulphate. These computed parameters were utilized to decipher the solute–solute and solute–solvent interactions of copper sulphate in an aqueous ethanol solution. The ion solvation behavior of copper sulphate in water and aqueous ethanol over the range of 298.15–313.15K was studied using the electrical conductivity principle. The Kraus–Bray and Shedlovsky models of conductivity were used to analyze the obtained conductance data. From the obtained data, the limiting molar conductance λ°m, association constant KA, energy of activation of the rating process (Ea), and related thermodynamic parameters were determined. The Walden product (λ°mη0) was determined. The standard thermodynamic parameters of association (ΔG°A, ΔH°A) were calculated and discussed. Increased ion–solvent and solvent–solvent interactions are indicated by limiting molar conductance values with an increasing amount of ethanol. The negative ΔG°A values indicate that the association processes in all of the studied systems are spontaneous processes. The negative estimation of (ΔH°A) demonstrates that the association processes is exothermic in nature

Modelling of a novel Stand-Alone, Solar Driven Agriculture Greenhouse Integrated With Photo Voltaic /Thermal (PV/T) Panels

This is the author accepted manuscriptThis paper presents an analytical study of a new stand-alone agriculture greenhouse (GH) system. This system utilizes the excess solar radiation (more than that required by the plants for photosynthetic process) to generate electricity via a set of Photo Voltaic/Thermal (PV/T) units which are placed on the GH roof and south side. In addition to electricity generation, PV/Ts reduce the cooling load of the GH and help the system to be naturally ventilated. The system recovers the GH air humidity, including the plants transpiration, and uses it as irrigating water. Two coupled mathematical models are developed using MATLAB. The first model calculates the absorbed and transmitted solar radiation by/through each GH surface for a Clear Sky Day. The results of the first model are used as inputs to the second one that predicts the GH performance (GH surfaces and air temperatures, air relative humidity, air velocity, water production, electricity production and power consumption). These models are applied on climate conditions of Zagazig city, Sharqia, Egypt. The results show that the system presents a good solution for water shortage in Egypt as it has the ability to provide suitable climate conditions for plant growth (high quality and quantity) and produce enough water for irrigation purposes.British CouncilScience & Technology Development Fund (STDF), Egyp

Urethral mobilization and advancement for distal hypospadias

Background/purpose Despite the existence of numerous techniques for the repair of distal penile hypospadias, none of them is completely satisfactory. Advancing the  urethra without mobilization for repair of glanular hypospadias has the advantage of avoiding a common problem occurring with other techniques: urethrocutaneous fistula. This study aims at evaluation of our experience with this technique for repair of distal hypospadias.Materials and methods A prospective study was conducted on patients with glanular, coronal and subcoronal hypospadias during the period from December 2012 to December 2014. Recurrent cases were excluded. Feasibility of the technique and postoperative complications were recorded.Results A total of 30 boys between 9 months and 7 yearsof age were included in the study. They underwent repair of  glanular (five), coronal (10), and subcoronal (15) hypospadias. The urethra was mobilized to the proximal shaft in almost all cases. Three cases developed postoperative hematoma, which were managed conservatively and resolved spontaneously. Two cases  developed wound infection and were managed with antibiotics and daily dressing until infection resolved. None of the patients had major complications such as dehiscence, urethral stricture, or fistula. Three patients developed meatal stenosis; two of them responded to repeated dilatation twice weekly for 2 weeks; and one needed meatoplasty. In one patient, the most distal of the glans approximation sutures disrupted, leading to a minor detachment in the glans. There was no recurrent chordee. Two patients underwent meatal retraction, wherein the urethra migrated proximally but still within the glans; only one of these patients required a second procedure.Conclusion The urethral mobilization technique seems tobe a good method for the repair of distal hypospadias with or without chordee with satisfactory cosmetic and functional results. The procedure has the advantage of avoiding the need for a second layer of tissue covering during repair. Moreover, there is no chance for the development of urethrocutaneous fistula, a major postoperative complication of other surgical techniques creating a neourethra. Postoperative management is simple and a brief hospital stay is sufficient.Keywords: distal hypospadias, hypospadias repair, urethral mobilizatio

Determination of optimum wave reflection of seawalls via experimental modeling

This paper presents and discusses the results of experimental investigations using both vertical and sloping seawalls configurations to determine the optimal wave reflection characteristics of seawalls for protecting beaches against erosion under a variety of hydrodynamic conditions. The different experiments include both of rectangular or triangular serrated blocks and slotted seawalls with or without triangular serrations as energy dissipaters. The linear wave theory is utilized. Moreover, the Dalrymple method is considered to predict the ordinates of the resultant standing wave due to the partial wave reflection. The study shows that the usage of slotted seawall with triangular serrations is superior compared to the other suggested energy dissipaters in reducing wave reflection whenever the waves become longer. The findings of the present investigation could be applied to optimize the design criteria of shore protection structures

Availability and Feasibility of Water Desalination as Non-conventional Resource for Agricultural Irrigation in the MENA Region: A review

This is the final version. Available on open access from MDPI via the DOI in this recordMany countries in the MENA region (Middle East and North Africa) are facing water scarcity, which poses a great challenge to agricultural production. Furthermore, water scarcity is projected to increase due to climate change, particularly in arid and semi-arid regions. The integration of solar power and water desalination systems in greenhouses to overcome water shortages is one of the preferred technologies in crop-growing areas. Crop growth control is done through sufficient management of environmental climatic variables as well as the quantity and quality of water and applied fertilisers with irrigation. Numerous crops such as cucumbers, tomatoes, peppers, lettuces, strawberries, flowers, and herbs can be grown under greenhouse conditions using desalinated water. This paper displays the state of the art in (i) solar-driven saltwater desalination to irrigate crops, (ii) the feasibility of water desalination for agriculture in the MENA region, (iii) the economics and environmental impacts of the desalination process, (iv) the quality of desalinated water compared with other non-conventional water resources and (v) recommendations for the future in the MENA region.Science, Technology, and Innovation Funding Authority (STIFA) of EgyptBritish Counci

Investigation of sediment accumulation in Nubia Lake, using RS/GIS

The main focus of this paper is to detect the changes in AHDL bed surface (sedimentation and erosion) in the period 2000-2012 in the active sedimentation zone of the Lake which is located in Nubia Lake (Sudanese part of AHDL). To enable this detection, the remote sensing (RS) and (Geographic Information Systems) GIS techniques are used to build the 3-D profile of the Lake portion where most of the sediment accumulate. Also, the accumulated sediment during this period is computed using the developed 3-D profile and using the cross section method as conducted by Aswan High Dam Authority (AHDA). Also, the surface areas of sedimentation and erosion are mapped and computed. Results indicated that sedimentation are dominant in years with high flood while erosion occurs when the incoming flow to the lake is low. Moreover, results indicate that the present approach overestimate the sedimentation amount by about 4% compared to the results of the method used by AHDA