8 research outputs found
Digital Banking, Corporate Governance, Ownership Structure, and Intellectual Capital Performance: Evidence From Indonesia
The base of the company's growth has changed, from tangible assets to intangible assets. Many companies recognize the importance of IC as performance drivers. This research aimed to examine the effect of the implementation of digital banking, corporate governance, family ownership, foreign ownership, and government ownership on Intellectual Capital (IC) performance; and examined the effect of interactions between corporate governance and ownership structure on IC performance in banking companies listed on the Indonesia Stock Exchange (IDX) during 2012-2016. This research used a regression method with panel data. The total observations were 130 cases. In this research, IC performance used Value Added Intellectual Coefficient (VAIC). We proved that the implementation of digital banking did no significant implications for IC performance in the same year because it was still in the process of developing. Family ownership, foreign ownership, government ownership, and the interaction between corporate governance and ownership structure did not affect IC performance. On the contrary, this research proved that corporate governance had significant implications for improving IC performance. JEL Classification: G31, G32, G34DOI: https://doi.org/10.26905/jkdp.v22i4.248
Study on the Malondialdehid Level of Diabetic Rat Implemented with Isolate 1.4-Bis-(3,4,5-Trimetoksi-Fenil)-Tetrahidro-Furo (3,4-C) Mahogani Seed Furan (Swietenia Macrophylla King)
Background: In diabetes mellitus (DM), hyperglycemia may increase malondialdehyde (MDA) levels. Isolates 1,4-bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furo (3,4-c) furan from mahogany (Swietenia macrophylla king) can lower blood glucose levels of diabetic rats. This study aimed to examine the blood MDA level of diabetic rats treated with the isolated seeds of mahogany.
Subjects and Method: This was an experimental study conducted at the Laboratory of Center for Food and Nutrition Studies, Inter-University Center, Gadjah Mada University, Yogyakarta. A sample of 36 male Wistar rats, 8-10 weeks old, body weight 200-250 grams, was divided randomly into 6 groups, namely: KN (normal control), K (-) (DM without therapy), K (+) (DM + glibenclamide 0.45 mg/kg BW), P1, P2, and P3 (DM + isolate of 10 mg/kgBW, 20 mg/kg BW, and 40mg/kg BW). Therapy was given for 21 consecutive days. Streptozotocin 45 mg/kgBW and nicotinamide 110 mg/kgBW were used to induce the occurrence of diabetic rats. Examination of blood MDA level was performed at H- (before mouse modelled DM), H0 (when mice were modelled DM but not yet treated), H7 (after 7 days of therapy), H14 (after 14 days of therapy), and H21 (after 21 days of therapy). MDA levels (nmol/mL) were measured by thiobarbituric acid reacting substances (TBARS) method. Data were analyzed by One Way ANOVA test followed by Tukey HSD and repeated ANOVA test followed by LSD.
Results: When H-, mean MDA levels of all groups within normal limits (<2 nmol/ mL), ie: KN 1.25 ± 0.16 nmol/ mL, K (-) 1.22 ± 0.14 nmol/ mL, K (+) 1.44 ± 0.23 nmol/ mL, P1 1.40 ± 0.14 nmol/ mL, P2 1.54 ± 0.07 nmol/ mL, P3 1.47 ± 0.17 nmol/ mL. When H0, mean MDA content at K (-) 8.83 ± 0.12 nmol/ mL, K (+) 8.94 ± 0.28 nmol/ mL, P1 9.01 ± 0.22 nmol/ mL, P2 9.00 ± 0.32 nmol/ mL, and P3 9.23 ± 0.42 nmol/ mL which means higher than normal, while the KN is still within normal limits, ie 1.42 ± 0.21 nmol/ mL. Within 21 days of treatment, mean MDA levels in each treatment group (K (+), P1, P2, and P3) showed significant decreases over time (H0 to H21). Differences in MDA levels between H0 and H7, H7 and H14, H14 and H21 showed p< 0.001. After 21 days of treatment (at H21) there was a significant difference between MDA and p< 0.001, except between pair-wise KN and K (+) with p= 0.724, KN and P3 with p= 0.865, and K (+) and P3 with p= 1.000 which means the difference is not meaningful.
Conclusion: Furan Seed isolation therapy is effective for reducing MDA levels. MDA levels of diabetic mice receiving 1.4-bis- (3,4,5-trimethoxy-phenyl) isolate therapy -tetrahydro-furo (3,4-c) furan from mahogany seeds (Swietenia macrophylla King) 40 mg/ kgBW decreased significantly until levels reached a normal state equivalent to mice receiving glibenclamide therapy.
Keywords: malondialdehyde, mahogany seed, isolate, diabete
The Antiplasmodial Activity of Chalcone Derivatives Through the Inhibition of Hemozoin Formation Andthe Increased Number of Stomatocytes
Background: Malaria remains an important public health problem in the world, particularly due to resistance to Plasmodium. The presence of resistance encourages research to find new antimalarials. One of the compounds which has antiplasmodial activity is chalcone derivative compound (E) – 1 – (4 – aminophenyl) – 3 – (2,3 – dimethoxyphenyl) prop – 2 – en – 1 – one. This study aimed to test if antiplasmodial compound worked by inhibiting Hemozoin formation and increasing the number of Stomatocytes.
Subjects and Method: This was an experimental laboratory study using a randomized controlled trial. The study was conducted from May 2016 until July 2017 in the laboratory of Parasitology and Clinical Pathology Faculty of Medicine, Universitas Gadjah Mada.A sample of Swiss mice wasrandomized into treatment group and control group.The independent variable was the administration of (E) – 1 – (4 – aminophenyl) – 3 – (2,3 – dimethoxyphenyl) prop – 2 – en – 1 – one. The dependent variable was the number of Hemozoin and Stomatocyte. Hemozoin level was measured by flow cytometry. The number of Stomatocytes was calculated from the peripheral blood picture stained with HE. The data were analyzed byt-test.
Results: The number of Hemozoin in the treatment group (mean= 0.31) was less than in the control group (mean= 3.20) and it was statistically significant (p< 0.001). The number of Stomatocytes in the treatment group (mean= 38.83) was higher than in the control group (mean= 0.83) and it was statistically significant (p< 0.001).
Conclusion: Substance (E) – 1 – (4 – aminophenyl) – 3 – (2,3 – dimethoxyphenyl) prop – 2 – en – 1 – one acts as an antimalarial by inhibiting Hemozoin formation and increasing the number of Stomatocytes.
Keywords: antimalarial, hemozoin, compound (E) – 1 – (4 – aminophenyl) – 3 – (2,3 – dimethoxyphenyl) prop – 2 – en – 1 – one, stomatocyte
Pembentukan dan Pelatihan Kader Kesehatan Anak Berkebutuhan Khusus tentang Protokol Kesehatan Masa Pandemi COVID-19
The incidence of COVID-19 in Indonesia is significantly increasing. In Indonesia, there were 965.283 confirmed cases and 27.453 people died of covid as of January 22, 2021. Meanwhile, the 7.505 confirmed cases and 352 death were from Surakarta. In this pandemic situation, the community must protect itself from being infected by the virus. Prevention is done by implementating the 5M health protocol, which are wearing mask, social distancing, and hand washing. Those health protocols are also part of clean and healthy lifestyle (PHBS). Special needs children (ABK) are those who have different characteristics than any other common children. Special health consideration should be given for those special needs child, including PHBS because of the special needs they are having and probable difficulties into implementing PHBS. The consideration can be given by their teacher, caretaker, parents, or trained social health workers in the hope of special needs children become independent into implementing the PHBS. The aim of this program is implementating social service program and helping special needs children to become independent in implementating PHBS and health protocol. The program was held by lecturing, demonstration, simulation, and supervised practice. This program hopefully will prevent either health issues or prevent the spreading of infective disease, specifically in this pandemic situation.Angka kejadian kasus baru COVID-19 di Indonesia meningkat secara signifikan. Data pada 22 Januari 2021 mencapai 965.283 kasus terkonfirmasi, 27.453 kematian, sedangkan untuk kota Surakarta mencapai 7.505 kasus terkonfirmasi, 352 kematian. Pada masa pandemi seperti saat ini semua masyarakat harus menjaga diri agar tidak tertular infeksi virus ini. Pencegahan yang dapat dilakuka dengan menerapkan protokol kesehatan 5M selama pandemi COVID-19 yaitu Memakai masker, Menjaga jarak, dan Mencuci tangan. Protokol kesehatan tersebut juga termasuk Perilaku Hidup Bersih dan Sehat (PHBS). Anak Berkebutuhan Khusus (ABK) adalah anak yang mempunyai karakteristik khusus yang membedakan dengan anak pada umumnya. Anak Berkebutuhan Khusus semestinya mendapatkan perhatian khusus dalam hal kesehatan, salah satunya melalui penerapan PHBS dikarenakan kemungkinan adanya karakteristik dan hambatan yang dimiliki. Perhatian dapat diberikan oleh guru di sekolah/ pendamping, orang tua di rumah, ataupun dari kader kesehatan yang terlatih dengan harapan nantinya ABK dapat memelihara PHBS secara mandiri. Tujuan pengabdian ini untuk melaksanakan komponen Pengabdian Kepada Masyarakat dan membantu kemandirian ABK dalam memelihara PHBS serta protokol kesehatan. Pengabdian dilakukan dengan metode ceramah, demonstrasi, simulasi, dan pendampingan praktik. Hal ini diharapkan dapat mencegah gangguan kesehatan maupun penularan penyakit infeksi khususnya di masa pandemi
Juvenile Delinquency as a Form of Coping in Broken Home Children
Juvenile delinquency is often considered to be a criminal act caused by a lack of education or attention from parents. However, when viewed through personality psychology, juvenile delinquency can occur due to other things. This study aimed to determine whether a broken home can cause delinquency in adolescents, assess the effect of family control on juvenile delinquency, determine the coping mechanisms that occurred in broken-home adolescents, and determine the impact of a broken home on adolescents’ behavior. We chose to compile this article by conducting a literature study of scientific articles, theses, and journals on the internet media and then drawing conclusions. The results showed that juvenile delinquency, such as skipping school, clubbing, and gang motorist, can happen because Sigmund Freud’s coping mechanism is to adapt to difficult situations in the form of a broken home and maintain his emotional health.
Keywords: Juvenile delinquency; coping; broken hom
Pengaruh Pembelajaran Poe (Predict Observe Explain) melalui Metode Eksperimen dan Demonstrasi terhadap Hasil Belajar Ditinjau dari Kemampuan Awal dan Keterampilan Generik Sains Siswa
The aims of this reasearch are to find out the influence of POE model through experiment and demonstration methods viewed by prior knowledge and generic science skill and the interaction of them to students' cognitive, afective, and phsycomotor learning achievements on environment pollution subject. The population of this reseach was all students of the seventh grade of MTs PPMI Assalam Sukoharjo. The sample of this reseach was determined by using cluster random sampling and the result got two classes. Experiment class I (7C) used POE model with experiment method and experiment class II used POE model with demonstration method. Data collected technique used test to get students' cognitive achievement, while observation sheets were used to get students' affective and phsycomotor acievements, and test sheets were used to get students' prior knowledge and generic science skill. Hypothesis was analyzed used ANAVA. The results of the research were as follow: There was influence of prior knowledge and generic science skill to the student cognitive achievement and also there was interaction between the POE model through experiment and demonstration methods, prior knowledge, and generic science skill to the students' cognitive achievement