72 research outputs found
Topology of the RNA polymerase active center probed by chimeric rifampicin-nucleotide compounds.
Full text linkNew Cross-Linking Quinoline and Quinolone Derivatives for Sensitive Fluorescent Labeling
Full text linkBactericidal activities of GM flax seedcake extract on pathogenic bacteria clinical strains
Full text linkLocalisation of a Region on Subunit B' Neighboring the Active Center of the RNA Polymerase from Methanobacterium thermoautotrophicum Strain W
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A route to RNA with an alkylating group at the 5'-triphosphate residue.
No full textReaction of ATP with N,N,N'-tris(2-chloroethyl), N' (p-formyl-phenyl)propylenediamine-1,3 (abbreviation C13R) afforded a gamma-ester of ATP (abbreviation C1RpppA) - the product of alkylation by an aliphatic nitrogen mustard residue of C13R. The alkylating activity of the aromatic nitrogen mustard residue of C1RpppA is suppressed by the electron-acceptor effect of the p-formyl group. C1RpppA is a substrate of RNA-polymerase, and affords RNA with C1RpppA-residues at the 5'-termini
The Significance of the Secondary Reactions Regularity for the Chemistry of Condensed Metal Phosphates
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A zinc-binding site in the largest subunit of DNA-dependent RNA polymerase is involved in enzyme assembly
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