36 research outputs found

    Contribution to the understanding of the Ionian Basin sedimentary evolution along the eastern edge of Apulia during the Late Cretaceous in Albania

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    Integrated in the peri-Adriatic domain, the Ionian Basin extended along a NW-SE direction during the Late Cretaceous, limited on its sides by the Apulian and the Kruja platforms. The basinal/slope succession was studied in seven outcrops exposed in the Albanian fold-and-thrust belt. Sedimentological investigations, supported by bio- and chronostratigraphy were performed on calcareous Upper Cretaceous hemipelagites, gravity-flow deposits and slumps. The western part of the basin was studied, revealing a strong influence of the Apulian margin, alternatively shedding sediment basinward, by means of a tectonically controlled edge. The Late Albian to Cenomanian period is characterized by the settling of muddy debrites along the margin. A deep basinal environment characterizes this period which prolongs until the Santonian, with no significant influx of the platform basinward. This sedimentary setting abruptly changed at the end of the Santonian, with an important influx derived from both platforms. Coarsening and thickening upward sequences show a progressive increase in sediment shedding during the Campanian. The Late Campanian-Early Maastrichtian period points out a major change on the resedimentation processes with the settling of several slumped units reworking thick sediment packages. The latter can be traced along the Apulian margin, testifying of instabilities along the edge of Apulia

    Competitive Reporter Monitored Amplification (CMA) - Quantification of Molecular Targets by Real Time Monitoring of Competitive Reporter Hybridization

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    Background: State of the art molecular diagnostic tests are based on the sensitive detection and quantification of nucleic acids. However, currently established diagnostic tests are characterized by elaborate and expensive technical solutions hindering the development of simple, affordable and compact point-of-care molecular tests. Methodology and Principal Findings: The described competitive reporter monitored amplification allows the simultaneous amplification and quantification of multiple nucleic acid targets by polymerase chain reaction. Target quantification is accomplished by real-time detection of amplified nucleic acids utilizing a capture probe array and specific reporter probes. The reporter probes are fluorescently labeled oligonucleotides that are complementary to the respective capture probes on the array and to the respective sites of the target nucleic acids in solution. Capture probes and amplified target compete for reporter probes. Increasing amplicon concentration leads to decreased fluorescence signal at the respective capture probe position on the array which is measured after each cycle of amplification. In order to observe reporter probe hybridization in real-time without any additional washing steps, we have developed a mechanical fluorescence background displacement technique. Conclusions and Significance: The system presented in this paper enables simultaneous detection and quantification of multiple targets. Moreover, the presented fluorescence background displacement technique provides a generic solution fo

    Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game

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    Cocaine addiction is characterized by impulsivity, impaired social relationships, and abnormal mesocorticolimbic reward processing, but their interrelationships relative to stages of cocaine addiction are unclear. We assessed blood-oxygenation-level dependent (BOLD) signal in ventral and dorsal striatum during functional magnetic resonance imaging (fMRI) in current (CCD; nβ€Š=β€Š30) and former (FCD; nβ€Š=β€Š28) cocaine dependent subjects as well as healthy control (HC; nβ€Š=β€Š31) subjects while playing an interactive competitive Domino game involving risk-taking and reward/punishment processing. Out-of-scanner impulsivity-related measures were also collected. Although both FCD and CCD subjects scored significantly higher on impulsivity-related measures than did HC subjects, only FCD subjects had differences in striatal activation, specifically showing hypoactivation during their response to gains versus losses in right dorsal caudate, a brain region linked to habituation, cocaine craving and addiction maintenance. Right caudate activity in FCD subjects also correlated negatively with impulsivity-related measures of self-reported compulsivity and sensitivity to reward. These findings suggest that remitted cocaine dependence is associated with striatal dysfunction during social reward processing in a manner linked to compulsivity and reward sensitivity measures. Future research should investigate the extent to which such differences might reflect underlying vulnerabilities linked to cocaine-using propensities (e.g., relapses)

    Contribution to the understanding of the Ionian Basin sedimentary evolution along the eastern edge of Apulia during the Late Cretaceous in Albania

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    Integrated in the peri-Adriatic domain, the Ionian Basin extended along a NW-SE direction during the Late Cretaceous, limited on its sides by the Apulian and the Kruja platforms. The basinal/slope succession was studied in seven outcrops exposed in the Albanian fold-and-thrust belt. Sedimentological investigations, supported by bio- and chronostratigraphy were performed on calcareous Upper Cretaceous hemipelagites, gravity-flow deposits and slumps. The western part of the basin was studied, revealing a strong influence of the Apulianmargin, alternatively shedding sediment basinward, by means of a tectonically controlled edge. The Late Albian to Cenomanian period is characterized by the settling of muddy debrites along themargin. A deep basinal environment characterizes this period which prolongs until the Santonian, with no significant influx of the platform basinward. This sedimentary setting abruptly changed at the end of the Santonian, with an important influx derived from both platforms. Coarsening and thickening upward sequences show a progressive increase in sediment shedding during the Campanian. The Late Campanian-Early Maastrichtian period points out a major change on the resedimentation processes with the settling of several slumped units reworking thick sediment packages. The latter can be traced along the Apulian margin, testifying of instabilities along the edge of Apulia.status: publishe

    Meter-scale cycles as a proxy for the evolution of the Apulian Carbonate Platform during the late Cretaceous (Llogara Pass, Albania)

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    Β© 2015, Springer-Verlag Berlin Heidelberg. Sedimentological investigations have revealed ten facies in Upper Cretaceous platform carbonates (1220Β m thick) at Llogara Pass in southern Albania that can be grouped into four facies associations. These reflect specific environmental conditions, ranging from intertidal to subtidal. The facies form small-scale patterns attesting to high-frequency/low-amplitude cyclicity characteristic of relative sea-level fluctuations. Meter-scale cycles have been classified into six distinct types and characterized on the basis of diagnostic surfaces, diagenetic features, and reservoir properties. A closer look at diagenetic and petrophysical features revealed a drastic porosity reduction at each cycle top (i.e., cycle boundary). This underlines a strong interconnection of facies types and reservoir properties at the cycle scale, thus impacting the whole carbonate succession. The cycle stacking pattern is a reflection of the sedimentary evolution during the late Cretaceous in this southern part of the Apulian Platform. (1) Meter-scale peritidal cycles suggest that the Cenomanian was characterized by stable shallow-water conditions. (2) Thick stromatolitic-dominated cycles typify Turonian deposits. Although the nature of the deposits indicates inner platform conditions, the long-term hiatus documented from Italy (Turonian bauxites) is not evidenced in Llogara. (3) The thin (a few tens of meters) Coniacian–Santonian interval suggests the onset of a significant tectonic control over the sedimentary dynamics, likely accompanied by morphological changes on the Apulian Platform and an emergence of rudist-dominated cycles. (4) Peritidal-subtidal cycles persist during the Campanian, accompanied by a broad development of rudist organisms that evidence significant and repeated relative sea-level rise. These data allow refinement of the general sedimentological evolution during the late Cretaceous on the Apulian Platform.status: publishe

    Comparative sorption studies of chromate by nano-and-micro sized Fe2O3 particles

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    The comparative adsorption studies of Cr (VI) on nano and micro-powder Fe2O3 were investigated using kinetics and batch adsorption techniques. The uptake of chromate onto both the oxides of iron was observed to be dependent on the pH, contact time, temperature, media dosage and concentration of chromate anions. The values of sorption maxima were higher in the case of Fe2O3 nanopowder than the micro-powder which can be ascribed to the high surface area and point of zero charge (PZC) of the former oxide. The Dubinin-Radushkivech and Langmuir models were found well fitted for the description of the batch adsorption data. The FTIR studies confirmed that the hexavalent chromium was adsorbed onto both the iron oxides in the form of the Cr2O72βˆ’

    Green decisions : demographics and consumer understanding of environmental labels

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    This research examined the demographic profiles of Australian green consumers in relation to their satisfaction of environmental labelling. It examined consumers&rsquo; understanding of labelling and empirically investigated the association of demographic profile of consumers with their attitudes towards such labels. The results indicated that some of the demographic variables were significant, which is largely consistent with earlier findings by other researchers in this area. Label dissatisfaction was higher in the older and middle age respondents. However, some respondents disagreed that labels were accurate while commenting that labels were easy to understand. The key issue arising from the findings is that in order to provide perception of accuracy in labels, it is an option to use Type I or Type III labelling on products. These labels are, arguably, more credible because they are endorsed by third party labelling experts. This would come at a cost and for green products that use third party labelling, they will also have to bear in mind to keep the prices competitive.<br /
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