Studies of the Woody Vegetation of the Welor Forest Reserve (Senegal) for Sustainable Use

The Welor area has been classified as a forest reserve since 1935 while waiting for the outcome of studies for its appropriate exploitation based on its biological potential. Due to lack of information on this potential, the plant resources of this forest reserve have been used improperly and excessively. The present study aims at gathering, with an appropriate approach and efficient tools, information necessary for designing a management plan to ensure a sustainable use of the woody resources of Welor Forest Reserve. The results obtained have provided information on the present condition of the woody flora and the vegetation, the potential and the dynamics of the most exploited woody species, and the root causes of the present state of the vegetation of the Welor Forest Reserve. Forty-six woody species, which belong to 39 genera and 25 families, were identified in this Forest Reserve. The most numerous families were Combretaceae, Capparidaceae, Mimosaceae and Caesalpiniaceae. The shrubs represented about 95% of the woody individuals. The average density of the woody individuals was 75–181 individuals per hectare. Acacia seyal and Balanites aegyptiaca were the dominant woody species with the best population structure. None of the woody species exploited for timber reveals a good structure and a good regeneration. Considering the socio-economic context of the area, it appears that the Welor Forest Reserve could be used as a source for firewood.West African Journal of Applied Ecology Vol. 13 2008: pp. 67-7

Élaboration de modèles allométriques d’Acacia Sénéga

La présente étude s’est appesantie sur l’élaboration de modèles allométriques d’une espèce soudanosahélienne (Acacia Sénégal ) dans le but d’asseoir une base de calcul des stocks de carbone. La recherche s’est effectuée en zone sylvopastorale, au nord du Sénégal. Au préalable, l’étude a tenté d’approfondir les connaissances sur la dendrométrie de Acacia Sénégal. Sur le terrain, les paramètres suivants ont été mesurés et fait l’objet d’analyses et interprétations : diamètre à la base, hauteur totale de l’arbre, longueur du tronc, diamètre à hauteur de poitrine, circonférence à hauteur de poitrine et largeur du houppier. La pesée des échantillons de chaque partie (tronc, branche, rameau) de l’échantillon d’arbres composés de 38 pieds d’Acacia Sénégal et leur séchage à l’étuve ont permis de connaître la biomasse sèche de chaque sujet. Ensuite, des modèles allométriques spécifiques (entre la biomasse sèche et les paramètres dendrométriques) ont été générés et les coefficients de corrélation déterminés. Les différentes analyses ont permis d’affirmer que le diamètre à hauteur de poitrine (DHP) est la variable qui offre la meilleure corrélation avec la biomasse aérienne. Parmi les modèles, et par ordre décroissant, nous avons obtenu la relation polynomiale, logarithmique et de puissance. Les modèles retenus ont comme entrée le DBH. De ce fait, le modèle polynomiale (y = 0,032DBH3 - 1,016DBH2 + 10,87DBH + 7,429) présente la meilleure corrélation (R² = 0,963), suivi du modèle logarithmique (y = 13,61ln(DBH) + 17,89) avec une corrélation R² = 0,933 et du modèle de puissance (y = 22,23DBH0,357) pour une corrélation R² = 0,909. L’étude a confirmé l’hypothèse selon laquelle, au sein d’une même espèce, l’élaboration de modèle spécifique reflète plus la réalité et permet de faire une quantification des stocks de carbone plus proche de la réalité que le modèle générique.Mots-clés : modèle allométrique, grande muraille verte, Acacia Sénégal, séquestration de carbone

Urban sprawl development and flooding at Yeumbeul suburb (Dakar-Senegal)

Rapid development of urban centers in Africa is becoming a serious challenge for the coming decades with a wide range of foreseen social, economical and environmental implications. With the natural growth of the population, urban demography has been boosted by rural exodus triggered by serious droughts and increasing rural poverty. With the small resources available for an adequate urban management and the lack of efficient urban policy, Dakar capital of Senegal is characterized by an out of control urbanization process. Among the many impacts noted, flooding has appeared recently as a major threat for poor population leaving in the suburbs of Dakar. This study carried out at the outskirts of the town, in Yeumbeul District (17°24’ North, 14°46’ West), tries from rainfall variability, Digital Terrain Model and land cover change analysis since 1954 to track the interactions between natural and human causes of flooding occurring regularly since 1989. This integrated approach shows that the flooding process is not a mere climate variability related issue, it is tightly bound with poor urban management and occupation of irregular, unsuited land devoted to natural process. Satisfaction of housing needs was, for most poor rural dwellers, only possible through informal land markets, forcing them to settle in cheap yet risky lands. The recent extreme rainfall events reveal that most of these urban sprawls are located in flood prone areas. Environmental impacts of these flooded settlements have been examined. Serious flooding of 2005 has been a great momentum for the State and several other stakeholders to initiate various strategies that are discussed in this paper.Key words: Flooding, rural migration, irregular settlements, Dakar, Senegal

Co-benefits, trade-offs, barriers and policies for greenhouse gas mitigation in the agriculture, forestry and other land use (AFOLU) sector

The agriculture, forestry and other land use (AFOLU) sector is responsible for approximately 25% of anthropogenic GHG emissions mainly from deforestation and agricultural emissions from livestock, soil and nutrient management. Mitigation from the sector is thus extremely important in meeting emission reduction targets. The sector offers a variety of cost-competitive mitigation options with most analyses indicating a decline in emissions largely due to decreasing deforestation rates. Sustainability criteria are needed to guide development and implementation of AFOLU mitigation measures with particular focus on multifunctional systems that allow the delivery of multiple services from land. It is striking that almost all of the positive and negative impacts, opportunities and barriers are context specific, precluding generic statements about which AFOLU mitigation measures have the greatest promise at a global scale. This finding underlines the importance of considering each mitigation strategy on a case-by-case basis, systemic effects when implementing mitigation options on the national scale, and suggests that policies need to be flexible enough to allow such assessments. National and international agricultural and forest (climate) policies have the potential to alter the opportunity costs of specific land uses in ways that increase opportunities or barriers for attaining climate change mitigation goals. Policies governing practices in agriculture and in forest conservation and management need to account for both effective mitigation and adaptation and can help to orient practices in agriculture and in forestry towards global sharing of innovative technologies for the efficient use of land resources. Different policy instruments, especially economic incentives and regulatory approaches, are currently being applied however, for its successful implementation it is critical to understand how land-use decisions are made and how new social, political and economic forces in the future will influence this process

Scholarly communication in transition: The use of question marks in the titles of scientific articles in medicine, life sciences and physics 1966–2005

The titles of scientific articles have a special significance. We examined nearly 20 million scientific articles and recorded the development of articles with a question mark at the end of their titles over the last 40 years. Our study was confined to the disciplines of physics, life sciences and medicine, where we found a significant increase from 50% to more than 200% in the number of articles with question-mark titles. We looked at the principle functions and structure of the titles of scientific papers, and we assume that marketing aspects are one of the decisive factors behind the growing usage of question-mark titles in scientific articles

Event attribution science in adaptation decision-making: the context of extreme rainfall in urban Senegal

Event attribution assesses the effect of climate change on individual extreme events. While scientists have suggested that results could be relevant for climate adaptation policy, this has had little empirical investigation, particularly in developing regions. Taking the case of Senegal, the national adaptation policy context regarding extreme precipitation and flooding in urban areas, and the scientific information needed to support this policy, is investigated using key informant interviews, a workshop and document analysis. Flooding in Senegal was found to be viewed primarily as an urban planning concern rather than a climate change issue, with actions to address the impacts focussing on current vulnerabilities of urban communities without considering changing climate risks. While stakeholders thought event attribution might be useful to inform about climate change impacts and future risks of extreme events, it is unclear whether there would be opportunity for this at present, due to the limited role climate information has in adaptation decision-making. While addressing vulnerability to extremes is necessary whether or not the risk is climate change-related, if long-term planning is to be resilient then knowledge about future changes in risks of extremes will need to be considered, even if individual events are not attributed to climate change

Evaluation of the Prognostic Value of IFN-γ Release Assay and Tuberculin Skin Test in Household Contacts of Infectious Tuberculosis Cases in Senegal

BACKGROUND: Chemoprophylaxis of contacts of infectious tuberculosis (TB) cases is recommended for TB control, particularly in endemic countries, but is hampered by the difficulty to diagnose latent TB infection (LTBI), classically assessed through response to the Tuberculin Skin Test (TST). Interferon-gamma release assays (IGRA) are proposed new tools to diagnose LTBI, but there are limited data on their ability to predict the development of active TB disease. To address this, we investigated the response to TST and IGRA in household contacts of infectious TB cases in a TB high-burden country and the potential correlation with development of TB. METHODOLOGY/PRINCIPAL FINDINGS: Prospective household contacts study conducted in two health centres in Dakar, Senegal. A total of 2679 household contacts of 206 newly detected smear and/or culture positive index TB cases aged 18 years or greater were identified A TST was performed in each contact and an ESAT6/CFP10 ELISPOT assay performed in a random sample of those. Contacts were followed-up for 24 months. TB was diagnosed in 52 contacts, an incidence rate of 9.27/1000 person-years. In univariable analysis, the presence of positive TST (> or = 10 mm) and ELISPOT (>32 SFC/million PBMC) responses at baseline were associated with active TB during follow-up: Rate Ratio [RR] = 2.32 (95%CI:1.12-4.84) and RR = 2.09 (95%CI:0.83-5.31), respectively. After adjustment for age, sex and proximity to index case, adjusted RRs were 1.51 (95%CI:0.71-3.19) and 1.98 (95%CI:0.77-5.09), respectively. Restricting analysis to the 40 microbiologically confirmed cases, the adjusted RR for positive ELISPOT was 3.61 (95%CI:1.03-12.65). The median ELISPOT response in contacts who developed TB was 5-fold greater than in those who did not develop TB (p = 0.02). CONCLUSIONS/SIGNIFICANCE: TST and IGRAs are markers of a contact of the immune system with tubercle bacilli. In a TB endemic area, a high ELISPOT response may reflect increased bacterial replication that may subsequently be associated with development of TB disease and may have a prognostic value. Further longitudinal data are needed to assess whether IGRAs are reliable markers to be used for targeting chemoprophylaxis

A Praziquantel Treatment Study of Immune and Transcriptome Profiles in Schistosoma haematobium-Infected Gabonese Schoolchildren.

BACKGROUND: Although Schistosoma haematobium infection has been reported to be associated with alterations in immune function, in particular immune hyporesponsiveness, there have been only few studies that have used the approach of removing infection by drug treatment to establish this and to understand the underlying molecular mechanisms. METHODS: Schistosoma haematobium-infected schoolchildren were studied before and after praziquantel treatment and compared with uninfected controls. Cellular responses were characterized by cytokine production and flow cytometry, and in a subset of children RNA sequencing (RNA-Seq) transcriptome profiling was performed. RESULTS: Removal of S haematobium infection resulted in increased schistosome-specific cytokine responses that were negatively associated with CD4+CD25+FOXP3+ T-cells and accompanied by increased frequency of effector memory T-cells. Innate responses to Toll like receptor (TLR) ligation decreased with treatment and showed positive association with CD4+CD25+FOXP3+ T-cells. At the transcriptome level, schistosome infection was associated with enrichment in cell adhesion, whereas parasite removal was associated with a more quiescent profile. Further analysis indicated that alteration in cellular energy metabolism was associated with S haematobium infection and that the early growth response genes 2 and 3 (EGR 2 and EGR3), transcription factors that negatively regulate T-cell activation, may play a role in adaptive immune hyporesponsiveness. CONCLUSIONS: Using a longitudinal study design, we found contrasting effects of schistosome infection on innate and adaptive immune responses. Whereas the innate immune system appears more activated, the adaptive immunity is in a hyporesponsive state reflected in alterations in CD4+CD25+FOXP3+ T-cells, cellular metabolism, and transcription factors involved in anergy

Chapter 11 - Agriculture, forestry and other land use (AFOLU)

Agriculture, Forestry, and Other Land Use (AFOLU) plays a central role for food security and sustainable development. Plants take up carbon dioxide (CO2) from the atmosphere and nitrogen (N) from the soil when they grow, re-distributing it among different pools, including above and below-ground living biomass, dead residues, and soil organic matter. The CO2 and other non-CO2 greenhouse gases (GHG), largely methane (CH4) and nitrous oxide (N2O), are in turn released to the atmosphere by plant respiration, by decomposition of dead plant biomass and soil organic matter, and by combustion. Anthropogenic land-use activities (e.g., management of croplands, forests, grasslands, wetlands), and changes in land use / cover (e.g., conversion of forest lands and grasslands to cropland and pasture, afforestation) cause changes superimposed on these natural fluxes. AFOLU activities lead to both sources of CO2 (e.g., deforestation, peatland drainage) and sinks of CO2 (e.g., afforestation, management for soil carbon sequestration), and to non-CO2 emissions primarily from agriculture (e.g., CH4 from livestock and rice cultivation, N2O from manure storage and agricultural soils and biomass burning. The main mitigation options within AFOLU involve one or more of three strategies: reduction / prevention of emissions to the atmosphere by conserving existing carbon pools in soils or vegetation that would otherwise be lost or by reducing emissions of CH4 and N2O; sequestration - enhancing the uptake of carbon in terrestrial reservoirs, and thereby removing CO2 from the atmosphere; and reducing CO2 emissions by substitution of biological products for fossil fuels or energy-intensive products. Demand-side options (e.g., by lifestyle changes, reducing losses and wastes of food, changes in human diet, changes in wood consumption), though known to be difficult to implement, may also play a role. Land is the critical resource for the AFOLU sector and it provides food and fodder to feed the Earth's population of ~7 billion, and fibre and fuel for a variety of purposes. It provides livelihoods for billions of people worldwide. It is finite and provides a multitude of goods and ecosystem services that are fundamental to human well-being. Human economies and quality of life are directly dependent on the services and the resources provided by land. Figure 11.1 shows the many provisioning, regulating, cultural and supporting services provided by land, of which climate regulation is just one. Implementing mitigation options in the AFOLU sector may potentially affect other services provided by land in positive or negative ways. In the Intergovernmental Panel on Climate Change (IPCC) Second Assessment Report (SAR) and in the IPCC Fourth Assessment Report (AR4), agricultural and forestry mitigation were dealt with in separate chapters. In the IPCC Third Assessment Report (TAR), there were no separate sectoral chapters on either agriculture or forestry. In the IPCC Fifth Assessment Report (AR5), for the first time, the vast majority of the terrestrial land surface, comprising agriculture, forestry and other land use (AFOLU), is considered together in a single chapter, though settlements (which are important, with urban areas forecasted to triple in size from 2000 global extent by 2030), are dealt with in Chapter 12. This approach ensures that all land-based mitigation options can be considered together; it minimizes the risk of double counting or inconsistent treatment (e.g., different assumptions about available land) between different land categories, and allows the consideration of systemic feedbacks between mitigation options related to the land surface. Considering AFOLU in a single chapter allows phenomena common across land-use types, such as competition for land and water, co-benefits, adverse side-effects and interactions between mitigation and adaptation to be considered consistently. The complex nature of land presents a unique range of barriers and opportunities, and policies to promote mitigation in the AFOLU sector need to take account of this complexity. In this chapter, we consider the competing uses of land for mitigation and for providing other services. Unlike the chapters on agriculture and forestry in AR4, impacts of sourcing bioenergy from the AFOLU sector are considered explicitly in a dedicated appendix. Also new to this assessment is the explicit consideration of food / dietary demand-side options for GHG mitigation in the AFOLU sector, and some consideration of freshwater fisheries and aquaculture, which may compete with the agriculture and forestry sectors, mainly through their requirements for land and / or water, and indirectly, by providing fish and other products to the same markets as animal husbandry. This chapter deals with AFOLU in an integrated way with respect to the underlying scenario projections of population growth, economic growth, dietary change, land-use change (LUC), and cost of mitigation. We draw evidence from both "bottom-up" studies that estimate mitigation potentials at small scales or for individual options or technologies and then scale up, and multi-sectoral "top-down" studies that consider AFOLU as just one component of a total multi-sector system response. In this chapter, we provide updates on emissions trends and changes in drivers and pressures in the AFOLU sector, describe the practices available in the AFOLU sector, and provide refined estimates of mitigation costs and potentials for the AFOLU sector, by synthesising studies that have become available since AR4. We conclude the chapter by identifying gaps in knowledge and data, providing a selection of Frequently Asked Questions, and presenting an Appendix on bioenergy to update the IPCC Special Report on Renewable Energy Sources and Climate Change Mitigation (SRREN)

Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi

Outer surface protein C (OspC) plays a pivotal role in mediating tick-to-host transmission and infectivity of the Lyme disease spirochete, Borreliella burgdorferi. OspC is a helical-rich homodimer that interacts with tick salivary proteins, as well as components of the mammalian immune system. Several decades ago, it was shown that the OspC-specific monoclonal antibody, B5, was able to passively protect mice from experimental tick-transmitted infection by B. burgdorferi strain B31. However, B5’s epitope has never been elucidated, despite widespread interest in OspC as a possible Lyme disease vaccine antigen. Here, we report the crystal structure of B5 antigen-binding fragments (Fabs) in complex with recombinant OspC type A (OspCA). Each OspC monomer within the homodimer was bound by a single B5 Fab in a side-on orientation, with contact points along OspC’s α-helix 1 and α-helix 6, as well as interactions with the loop between α-helices 5 and 6. In addition, B5’s complementarity-determining region (CDR) H3 bridged the OspC-OspC′ homodimer interface, revealing the quaternary nature of the protective epitope. To provide insight into the molecular basis of B5 serotype specificity, we solved the crystal structures of recombinant OspC types B and K and compared them to OspCA. This study represents the first structure of a protective B cell epitope on OspC and will aid in the rational design of OspC-based vaccines and therapeutics for Lyme disease