7,116 research outputs found

    The health state preferences and logistical inconsistencies of New Zealanders: a tale of two tariffs

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    Notwithstanding the proposed use of Cost-Utility Analysis (CUA) to inform health care priority setting in New Zealand, to date there has been no research into New Zealanders’ valuations of health-related quality of life. This paper reports the results of a study of the health state preferences of adult New Zealanders generated from a postal survey to which 1360 people responded (a 50% response rate). The survey employed a self-completed questionnaire in which a selection of health states were described using the EQ-5D health state classification system and respondents’ valuations were sought using a visual analogue scale (VAS). Close attention is paid to the quality of the data, in particular to the ‘logical inconsistencies’ in respondents’ valuations. Regression analysis is used to interpolate values over the 245 possible EQ-5D states. Two tariffs of health state preferences, arising from contrasting treatments of the logical inconsistencies, are reported.New Zealand, EuroQol, EQ-5D

    Phototesting and photoprotection in LE

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    Photosensitivity and induction of skin lesions following UV radiation is a common problem of patients with cutaneous and systemic forms of lupus erythematosus. The detrimental effect of UV radiation to patients with lupus erythematosus was already recognized in the last century. Skin lesions can now be provoked under standardized conditions allowing the diagnosis and classification of patients with photosensitive disorders. The aim of this review is to give an overview on the history, test procedure and test results in patients with lupus erythematosus

    Kaposi's sarcoma in a patient with erythroblastopenia and thymoma: Reactivation after topical corticosteroids

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    We report a 69-year-old female with erythroblastopenia and thymoma who developed lesions of Kaposi's sarcoma (KS) after thymectomy, 2 months after the initiation of therapy with methylprednisolone. Control of mucocutaneous KS lesions was obtained with radiotherapy, interferon alfa-2b and withdrawal of systemic immunosuppressive therapy. Erosive oral lichen planus appeared later, and after therapy with topical corticosteroids a new lesion of KS developed that regressed after withdrawal of topical corticosteroids. The detection of HHV-8 only in lesional skin supports the hypothesis that this virus can trigger the development of KS lesions

    The quantum paraelectric behavior of SrTiO_{3} revisited: relevance of the structural phase transition temperature

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    It has been known for a long time that the low temperature behavior shown by the dielectric constant of quantum paraelectric SrTiO3SrTiO_{3} can not be fitted properly by Barrett's formula using a single zero point energy or saturation temperature (T1T_{1}). As it was originally shown [K. A. M\"{u}ller and H. Burkard, Phys. Rev. B {\bf 19}, 3593 (1979)] a crossover between two different saturation temperatures (T1lT_{1l}=77.8K and T1hT_{1h}=80K) at T10KT\sim10K is needed to explain the low and high temperature behavior of the dielectric constant. However, the physical reason for the crossover between these two particular values of the saturation temperature at T10KT\sim10K is unknown. In this work we show that the crossover between these two values of the saturation temperature at T10KT\sim10K can be taken as a direct consequence of (i) the quantum distribution of frequencies g(Ω)Ω2g(\Omega)\propto\Omega^{2} associated with the complete set of low-lying modes and (ii) the existence of a definite maximum phonon frequency given by the structural transition critical temperature TtrT_{tr}.Comment: 8 pages, 3 figure
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