58,025 research outputs found
The effect of disorder on the wave propagation in one-dimensional periodic optical systems
The influence of disorder on the transmission through periodic waveguides is
studied. Using a canonical form of the transfer matrix we investigate
dependence of the Lyapunov exponent on the frequency and
magnitude of the disorder . It is shown that in the bulk of the bands
, while near the band edges it has the order . This dependence is illustrated by numerical simulations.Comment: 15 pages, 4 figure
Virtual Site as an aid to first-year learning
Courses run by the School of the Built Environment have a range of entry requirements that enable diverse students and those with lower academic qualifications to gain entry. This results in a particular challenge for the Documentation & Estimating module, which is a very practical, skillsand competence-based module. It is delivered to large tutorial cohorts of mixed courses, abilities, ages and experience. Many students need one-toone guidance to understand what, practically, they have to do. They are given the theory first in a lecture and then have practical tutorials to carry out assessed exercises with limited tutor contact time. The module includes some basic surveying techniques and a levelling exercise which involves the transfer of a level from an assumed benchmark to establish a temporary benchmark some distance away. Many students have problems with computation of results. In spite of a careful introduction and explanation of the use of the instruments and techniques, many students find it difficult to visualise what is happening
Theory of plasmon-enhanced high-harmonic generation in the vicinity of metal nanostructures in noble gases
We present a semiclassical model for plasmon-enhanced high-harmonic
generation (HHG) in the vicinity of metal nanostructures. We show that both the
inhomogeneity of the enhanced local fields and electron absorption by the metal
surface play an important role in the HHG process and lead to the generation of
even harmonics and to a significantly increased cutoff. For the examples of
silver-coated nanocones and bowtie antennas we predict that the required
intensity reduces by up to three orders of magnitudes and the HHG cutoff
increases by more than a factor of two. The study of the enhanced high-harmonic
generation is connected with a finite-element simulation of the electric field
enhancement due to the excitation of the plasmonic modes.Comment: 4 figure
Delayed surgical debridement in pediatric open fractures: a systematic review and meta-analysis.
Purpose: Open fractures are considered orthopedic emergencies that are traditionally treated with surgical debridement within 6 h of injury to prevent infection. However, this proclaimed “6-h rule” is arbitrary and not based on rigorous scientific evidence. The aim of our study was to systematically review the literature that compares late (>6 h from the time of injury) to early (<6 h from the time of injury) surgical debridement of pediatric open fractures.
Methods: We searched several databases from 1946 to 2013 for any observational or experimental studies that evaluated late and early surgical debridement of pediatric open fractures. We performed a meta-analysis using a random effects model to pool odds ratios for a comparison of infection rates between children undergoing late versus early surgical debridement. We also investigated the infection rates in upper- and lower-limb pediatric open fractures. Descriptive, quantitative, and qualitative data were extracted.
Results: Of the 12 articles identified, three studies (retrospective cohort studies) were eligible for the meta-analysis, encompassing a total of 714 open fractures. The pooled odds ratio (OR = 0.79) for infection between late and early surgical debridement was in favor of late surgical debridement but was not statistically significant (95 % CI 0.32, 1.99; p = 0.38, I 2 = 0 %). No significant difference in infection rate was detected between pediatric open fractures in the upper and lower limbs according to the time threshold in the included studies (OR = 0.72, 95 % CI 0.29, 1.82; p = 0.40, I 2 = 0 %).
Conclusions: The cumulative evidence does not, at present, indicate an association between late surgical debridement and higher infection rates in pediatric open fractures. However, initial expedient surgical debridement of open fractures in children should always remain the rule. Thus, multi-center randomized controlled trials or prospective cohort studies will be able to answer this question with more certainty and a higher level of evidence
Plasma Processing of Large Curved Surfaces for SRF Cavity Modification
Plasma based surface modification of niobium is a promising alternative to
wet etching of superconducting radio frequency (SRF) cavities. The development
of the technology based on Cl2/Ar plasma etching has to address several crucial
parameters which influence the etching rate and surface roughness, and
eventually, determine cavity performance. This includes dependence of the
process on the frequency of the RF generator, gas pressure, power level, the
driven (inner) electrode configuration, and the chlorine concentration in the
gas mixture during plasma processing. To demonstrate surface layer removal in
the asymmetric non-planar geometry, we are using a simple cylindrical cavity
with 8 ports symmetrically distributed over the cylinder. The ports are used
for diagnosing the plasma parameters and as holders for the samples to be
etched. The etching rate is highly correlated with the shape of the inner
electrode, radio-frequency (RF) circuit elements, chlorine concentration in the
Cl2/Ar gas mixtures, residence time of reactive species and temperature of the
cavity. Using cylindrical electrodes with variable radius, large-surface
ring-shaped samples and d.c. bias implementation in the external circuit we
have demonstrated substantial average etching rates and outlined the
possibility to optimize plasma properties with respect to maximum surface
processing effect
Reduced Phagocytic Capacity of Blood Monocyte/Macrophages in Tuberculosis Patients Is Further Reduced by Smoking.
Tuberculosis (TB) and tobacco use are two major alarming global health issues posing immense threats to human populations. Mycobacterium tuberculosis (MTB) by activation of macrophages could induce the sequences of cells activation and releases of inflammatory cytokines such as CXCL-8, Il-12 and TNF-α which in turn induces the immune system network. However no information is available on other activity of cells by MTB and smoking. In the current study we aimed to investigate the serum levels TNF-a, CXCL-8 and phagocytosis capacity in tuberculosis patients with and without smoking. 103 subjects entered the study including 61 new diagnosed pulmonary TB patients (23 smokers and 38 nonsmokers) and 42 control healthy subjects. The phagocytosis of fluorescein isothiocyanate dextran (FITC-dextran) in blood monocytes/macrophages through flowcytometry was assessed. Serum levels of TNF-a and CXCL-8 were analyzed by ELISA methods. A lower percentage of cells from TB patients who smoked [50.29% (43.4-57.2), p<0.01] took up FITC-dextran after 2h compared to non-smoking TB subjects [71.62% (69.2-74.1)] and healthy cases [97.45% (95.9-99.1). Phagocytic capacity was inversely correlated with cigarette smoking as measured by pack years (r=-0.73, p<0.001). The serum levels of TNF-a and CXCL-8 were significantly higher in the TB patients who smoked compared to the TB non-smoker group (p<0.001, p<0.01 respectively). Blood monocytes/macrophages from TB patients have reduced phagocytic capacity which is further reduced in TB patients who smoke. Smoking enhanced serum levels of TNF-a and CXCL-8 suggesting a greater imbalance between the proinflammatory and anti-inflammatory factors in these patients
SiGeC alloy layer formation by high-dose C + implantations into pseudomorphic metastable Ge0.08Si0.92 on Si(100)
Dual-energy carbon implantation (1 × 1016/cm2 at 150 and at 220 keV) was performed on 260-nm-thick undoped metastable pseudomorphic Si(100)/ Ge0.08Si0.92 with a 450-nm-thick SiO2 capping layer, at either room temperature or at 100 °C. After removal of the SiO2 the samples were measured using backscattering/channeling spectrometry and double-crystal x-ray diffractometry. A 150-nm-thick amorphous layer was observed in the room temperature implanted samples. This layer was found to have regrown epitaxially after sequential annealing at 550 °C for 2 h plus at 700 °C for 30 min. Following this anneal, tensile strain, believed to result from a large fraction of substitutional carbon in the regrown layer, was observed. Compressive strain, that presumably arises from the damaged but nonamorphized portion of the GeSi layer, was also observed. This strain was not significantly affected by the annealing treatment. For the samples implanted at 100 °C, in which case no amorphous layer was produced, only compressive strain was observed. For samples implanted at both room temperature and 100 °C, the channelled backscattering yield from the Si substrate was the same as that of the virgin sample
- …
