A Survey for Infall Motions toward Starless Cores. II. CS(2−1)CS (2-1) and N2H+(1−0)N_2H^+ (1-0) Mapping Observations

We present the results of an extensive mapping survey of 53 `starless' cores in the optically thick line of CS 2-1 and the optically thin lines of N2H+ 1-0 and C18O 1-0. The purpose of this survey was to search for signatures of extended inward motions. This study finds 10 `strong' and 9 `probable' infall candidates, based on $\delta V_{CS}$ analysis and on the spectral shapes of CS lines. From our analysis of the blue-skewed CS spectra and the $\delta V_{CS}$ parameter, we find typical infall radii of 0.06-0.14 pc. Also, using a simple two layer radiative transfer model to fit the profiles, we derive one-dimensional infall speeds, half of whose values lie in the range of 0.05-0.09 km s$^{-1}$. These values are similar to those found in L1544 by Tafalla et al., and this result confirms that infall speeds in starless cores are generally faster than expected from ambipolar diffusion in a strongly sub-critical core. In addition, the observed infall regions are too extended to be consistent with the `inside-out' collapse model applied to a very low-mass star. In the largest cores, the spatial extent of the CS spectra with infall asymmetry is larger than the extent of the $\rm N_2H^+$ core by a factor of 2-3. All these results suggest that extended inward motions are a common feature in starless cores, and that they could represent a necessary stage in the condensation of a star-forming dense core.Comment: Two tex files for manuscript and tables, and 38 figures. To appear in ApJ

Increased incidence of Mycoplasma pneumoniae infection in Finland, 2010-2011

Peer reviewe

A Catalogue of Optically Selected Cores

We present a new catalogue of 406 dense cores optically selected by using the STScI Digitized Sky Survey (DSS). In this catalogue 306 cores have neither an Embedded YSO (EYSO) nor a Pre-Main-Sequence (PMS) star, 94 cores have EYSOs (1 core has both an EYSO and a PMS star), and 6 cores have PMS star only. Our sample of dense cores in the catalogue is fairly complete within a category of northern Lynds class 5, 6 clouds, and southern Hartley et al. (1986)'s class A clouds, providing a database useful for the systematic study of dense cores. Most of the cores listed in the catalogue have diameters between $0.05 - 0.36$ pc with a mean of $\sim 0.24$ pc. The sizes ($\sim 0.33$ pc in the mean) of cores with EYSOs are found to be usually larger than the sizes ($\sim 0.22$ pc in the mean) of starless cores. The typical mean gas density of the cores is $\sim7\times 10^3 cm^{-3}$. Most of the cores are more likely elongated than spherical (mean aspect ratio: $\sim 2.4$). The ratio of the number of cores with EYSOs to the number of starless cores for our sample is about 0.3, suggesting that the typical lifetime of starless cores is $0.3-1.6$ Myr, about 3 times longer than the duration of the Class 0 and Class I phases. This lifetime is shorter than expected from models of ambipolar diffusion, by factors of 2-44.Comment: 22 pages, 8 figures, 3 tables, and to appear in ApJS. Harvard-Smithsonian Center for Astrophysic

A Near-Infrared Imaging Survey of Coalsack Globule 2

We describe a near-infrared imaging survey of Globule 2 in the Coalsack. This Bok globule is the highest density region of this southern hemisphere molecular cloud and is the most likely location for young stars in this complex. The survey is complete for K < 14.0, H < 14.5, and J < 15.5, several magnitudes more sensitive than previous observations of this globule. From the large number of background stars, we derive an accurate near-infrared extinction law for the cloud. Our result, E_{J-H}/E_{H-K} = 2.08 \pm 0.03, is significantly steeper than results for other southern clouds. We use the J-H/H-K color-color diagram to identify two potential young stars with K < 14.0 in the region. We apply H-band star counts to derive the density profile of the Coalsack Globule 2 and use a polytropic model to describe the internal structure of this small cloud. For a gas temperature T \sim 15 K, this globule is moderately unstable.Comment: 19 pages, manuscript format; 6 figures -- Accepted by A

Ascitic complement system in ovarian cancer

Ovarian cancer spreads intraperitoneally and forms fluid, whereby the diagnosis and therapy often become delayed. As the complement (C) system may provide a cytotoxic effector arm for both immunological surveillance and mAb-therapy, we have characterised the C system in the intraperitoneal ascitic fluid (AF) from ovarian cancer patients. Most of the AF samples showed alternative and classical pathway haemolytic activity. The levels of C3 and C4 were similar to or in the lower normal range when compared to values in normal sera, respectively. However, elevated levels of C3a and soluble C5b-9 suggested C activation in vivo. Malignant cells isolated from the AF samples had surface deposits of C1q and C3 activation products, but not of C5b-9 (the membrane attack complex; MAC). Activation could have become initiated by anti-tumour cell antibodies that were detected in the AFs and/or by changes on tumour cell surfaces. The lack of MAC was probably due to the expression of C membrane regulators CD46, CD55 and CD59 on the tumour cells. Soluble forms of C1 inhibitor, CD59 and CD46, and the alternative pathway inhibitors factor H and FHL-1 were present in the AF at concentrations higher than in serum samples. Despite the presence of soluble C inhibitors it was possible to use AF as a C source in antibody-initiated killing of ovarian carcinoma cells. These results demonstrate that although the ovarian ascitic C system fails as an effective immunological surveillance mechanism, it could be utilised as an effector mechanism in therapy with intraperitoneally administrated mAbs, especially if the intrinsic C regulators are neutralised