10 research outputs found
Determinants of Low Inflation in an Emerging, Small Open Economy through the Lens of Aggregated and Disaggregated Approach
Cooperation of the National Institute of Telecommunications with selected foreign partners
Artykuł przedstawia pokrótce historię międzynarodowej współpracy Instytutu Łączności – Państwowego Instytutu Badawczego (IŁ) w wybranych dziedzinach, ze szczególnym uwzględnieniem najistotniejszych międzynarodowych konferencji, których był inicjatorem i organizatorem oraz w zakresie współpracy w ramach najważniejszych organizacji międzynarodowych (ITU, CEPT, IEC, IALA-IMO, ETSI, URSI, IEEE-EMCS, ICTP, OWŁ/RWPG).The article briefly presents the history of international cooperation of the National Institute of Telecommunications in selected fields of activities, with particular focus on the most important international conferences, of which Institute was the initiator and organizer and in the field of cooperation within the most important international organizations (ITU, CEPT, IEC, IALA-IMO, ETSI, URSI, IEEE-EMCS, ICTP, OWŁ / RWPG)
Correlation of Migration Distance of Peptides in High-Performance Thin-Layer Chromatography and Pressurized Planar Electrochromatography Systems
Separation of 9-Fluorenylmethyloxycarbonyl Amino Acid Derivatives in Micellar Systems of High-Performance Thin-Layer Chromatography and Pressurized Planar Electrochromatography
Solvent front position extraction procedure with thin-layer chromatography as a mode of multicomponent sample preparation for quantitative analysis by instrumental technique
Efficacy and safety of lenalidomide treatment in multiple myeloma (MM) patients-Report of the Polish Myeloma Group
Pressurized planar electrochromatography of DNS amino acids derivatives in silica gel and silanized silica gel systems with formic acid addition to the water mobile phase
Response to anti-SARS-CoV-2 mRNA vaccines in multiple myeloma and chronic lymphocytic leukemia patients
Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) patients have increased morbidity and mortality rates of COVID-19 due to immunosuppression associated with the disease and ongoing therapy. The same immune impairment accompanying CLL and MM also affects suboptimal vaccine response. The study assessed the effectiveness of the humoral and T cell-mediated immunity following mRNA COVID-19 vaccination (using either BNT162b2 or mRNA-1273) in short-term (2-5 weeks after 2(nd) dose) and long-term follow-up (12 weeks after vaccination). Between March and August 2021, blood samples were obtained from 62 CLL and 60 MM patients from eight different hematology departments in Poland. Total anti-RBD antibodies were detected in 37% MM patients before vaccination, increased to 91% and 94% in short- and long-term follow-up, respectively. In CLL, serological responses were detectable in 21% of patients before vaccination and increased to 45% in the short-term and 71% in long-term observation. We detected a tendency to higher frequencies of specific CD8+ T cells against SARS-CoV-2 after vaccination compared to samples before vaccination in MM patients and no changes in frequencies of specific T cells in CLL patients. This study provides novel insights into mRNA vaccination efficacy in immunocompromised MM and CLL patients, and our findings highlight that specific CD8+ T cells against SARS-CoV-2 might be induced by vaccination but do not correlate positively with serological responses