3,880 research outputs found

    Contextual and Mediating Factors in Body Image Dissatisfaction

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    The purpose of this study was to examine the specific nature of the interaction and contribution of variables related to body image in a nonclinical population using a path analysis. This paper discusses various theoretical models and variables in the development and maintenance of body image dissatisfaction and eating concerns. Several variables and personality traits have been suggested as etiological factors in the development of body image dissatisfaction. These variables stem from different theoretical models. The five theoretical models discussed are: (1) Developmental, (2) Social-comparison, (3), Self-discrepancy, (4) Self-objectification, and (5) Feminist theory. From these broad theoretical models, many variables are viewed as risk factors for developing and maintaining eating and body image concerns. Six of the more prominent variables are explored, including sociocultural influence, family environment, perfectionism, gender-role orientation, stress, and guilt/shame. My hypothesized path model consists of two contextual (exogenous) variables and five mediating (endogenous) variables. The two variables of family and media influences are hypothesized to be the strongest path variables to body image dissatisfaction. Therefore, the exogenous variables are hypothesized to have an effect on the mediating variables, but are not affected by the other variables

    Semi-Supervised Learning with Graphs: Covariance Based Superpixels for Hyperspectral Image Classification

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    In this paper, we present a graph-based semi-supervised framework for hyperspectral image classification. We first introduce a novel superpixel algorithm based on the spectral covariance matrix representation of pixels to provide a better representation of our data. We then construct a superpixel graph, based on carefully considered feature vectors, before performing classification. We demonstrate, through a set of experimental results using two benchmarking datasets, that our approach outperforms three state-of-the-art classification frameworks, especially when an extremely small amount of labelled data is used.Case Studentship with the NP

    Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling protein

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    We report the cloning and functional characterization of myopodin, the second member of the synaptopodin gene family. Myopodin shows no significant homology to any known protein except synaptopodin. Northern blot analysis resulted in a 3.6-kb transcript for mouse skeletal and heart muscle. Western blots showed an 80-kD signal for skeletal and a 95-kD signal for heart muscle. Myopodin contains one PPXY motif and multiple PXXP motifs. Myopodin colocalizes with α-actinin and is found at the Z-disc as shown by immunogold electron microscopy. In myoblasts, myopodin shows preferential nuclear localization. During myotube differentiation, myopodin binds to stress fibers in a punctuated pattern before incorporation into the Z-disc. Myopodin can directly bind to actin and contains a novel actin binding site in the center of the protein. Myopodin has actin-bundling activity as shown by formation of latrunculin-A–sensitive cytosolic actin bundles and nuclear actin loops in transfected cells expressing green fluorescent protein–myopodin. Under stress conditions, myopodin accumulates in the nucleus and is depleted from the cytoplasm. Nuclear export of myopodin is sensitive to leptomycin B, despite the absence of a classical nuclear export sequence. We propose a dual role for myopodin as a structural protein also participating in signaling pathways between the Z-disc and the nucleus

    The Role of Demographic and Clinical Characteristics on Risk of COVID-19 Related Infection and Mortality

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    Since the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) which causes Covid-19, global health systems have struggled to cope with the rising number of related infections, acute admissions and mortalities. Poorer clinical outcomes have been observed amongst older patients with Covid-19 and males, and in those who are obese or who have darker skin(1) . Additionally, poorer outcomes including increased mortality have been associated with low vitamin D status(2,3) . The current observational study aimed to elucidate the association between patient demographic, anthropometric, clinical and biometric characteristics and Covid-19 disease severity and mortality

    Photodisintegration of the triton with realistic potentials

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    The process γ+t→n+d\gamma + t \to n + d is treated by means of three-body integral equations employing in their kernel the W-Matrix representation of the subsystem amplitudes. As compared to the plane wave (Born) approximation the full solution of the integral equations, which takes into account the final state interaction, shows at low energies a 24% enhancement. The calculations are based on the semirealistic Malfliet-Tjon and the realistic Paris and Bonn B potentials. For comparison with earlier calculations we also present results for the Yamaguchi potential. In the low-energy region a remarkable potential dependence is observed, which vanishes at higher energies.Comment: 16 pages REVTeX, 8 postscript figures included, uses epsfig.st

    A framework for power analysis using a structural equation modelling procedure

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    BACKGROUND: This paper demonstrates how structural equation modelling (SEM) can be used as a tool to aid in carrying out power analyses. For many complex multivariate designs that are increasingly being employed, power analyses can be difficult to carry out, because the software available lacks sufficient flexibility. Satorra and Saris developed a method for estimating the power of the likelihood ratio test for structural equation models. Whilst the Satorra and Saris approach is familiar to researchers who use the structural equation modelling approach, it is less well known amongst other researchers. The SEM approach can be equivalent to other multivariate statistical tests, and therefore the Satorra and Saris approach to power analysis can be used. METHODS: The covariance matrix, along with a vector of means, relating to the alternative hypothesis is generated. This represents the hypothesised population effects. A model (representing the null hypothesis) is then tested in a structural equation model, using the population parameters as input. An analysis based on the chi-square of this model can provide estimates of the sample size required for different levels of power to reject the null hypothesis. CONCLUSIONS: The SEM based power analysis approach may prove useful for researchers designing research in the health and medical spheres

    Influence of Gamma-Ray Emission on the Isotopic Composition of Clouds in the Interstellar Medium

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    We investigate one mechanism of the change in the isotopic composition of cosmologically distant clouds of interstellar gas whose matter was subjected only slightly to star formation processes. According to the standard cosmological model, the isotopic composition of the gas in such clouds was formed at the epoch of Big Bang nucleosynthesis and is determined only by the baryon density in the Universe. The dispersion in the available cloud composition observations exceeds the errors of individual measurements. This may indicate that there are mechanisms of the change in the composition of matter in the Universe after the completion of Big Bang nucleosynthesis. We have calculated the destruction and production rates of light isotopes (D, 3He, 4He) under the influence of photonuclear reactions triggered by the gamma-ray emission from active galactic nuclei (AGNs). We investigate the destruction and production of light elements depending on the spectral characteristics of the gamma-ray emission. We show that in comparison with previous works, taking into account the influence of spectral hardness on the photonuclear reaction rates can increase the characteristic radii of influence of the gamma-ray emission from AGNs by a factor of 2-8. The high gamma-ray luminosities of AGNs observed in recent years increase the previous estimates of the characteristic radii by two orders of magnitude. This may suggest that the influence of the emission from AGNs on the change in the composition of the medium in the immediate neighborhood (the host galaxy) has been underestimated.Comment: 13 pages, 13 figures, 3 table

    Designing Research

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    The aim of this chapter is to set out a process that researchers can follow to design a robust quantitative research study of occupant behavior in buildings. Central to this approach is an emphasis on intellectual clarity around what is being measured and why. To help achieve this clarity, researchers are encouraged to literally draw these relationships out in the form of a concept map capturing the theoretical model of the cause and effect between occupant motivations and energy use. Having captured diagrammatically how the system is thought to work, the next step is to formulate research questions or hypotheses capturing the relationship between variables in the theoretical model, and to start to augment the diagram with the measurands (things that can actually be measured) that are good proxies for each concept. Once these are identified, the diagram can be further augmented with one or more methods of measuring each measurand. The chapter argues that it is necessary to carefully define concepts and their presumed relationships, and to clearly state research questions and identify what the researcher intends to measure before starting data collection. The chapter also explains the ideas of reliability, validity, and uncertainty, and why knowledge about them is essential for any researcher
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