The van allen radiation belt

Van Allen radiation belt and energetic protons and electrons trapped in geomagnetic fiel

Institutional Characteristics and the Relationship Between Student's Last-Year University and Final-Year Secondary School Academic Performance.

A study of academic results of a student cohort in a diverse faculty of a large multi-campus university indicates that students' first-year performance at university is related to their prior academic achievement at secondary school, both overall and discipline specific, but that the extent and form of the relationship can vary by subject area and institutional secondary school and university characteristics. This may have implications for university selection and specification of prerequisite subjects for courses.EDUCATION ; STUDENTS ; INSTITUTION BUILDING

Calibration of pressure-dependent sensitivity and discrimination in Nier-type noble gas ion sources

The efficiency of many noble gas mass spectrometers to ionize gas species is known to be a function of the pressure of gas in the spectrometer. This work shows how the half plate voltage for maximum He or Ar signal depends on the spectrometer pressure and shows that the half plate voltage for maximum 4He sensitivity does not coincide with the half plate voltage for maximum 3He sensitivity. In addition, half plate voltage has a greater control on sensitivity at higher spectrometer pressures. Variations in He and Ar sensitivity and isotopic discrimination as a function of pressure are due, at least in part, to these variations in the position of maximum sensitivity with respect to half plate voltage. The maximum sensitivity settings shift to lower half plate voltage at high spectrometer pressures, irrespective of if the pressure increase is due to the gas being investigated or a different species. Therefore noble gas mass spectrometers should always be tuned at the maximum possible pressure; measurements at higher pressures should be avoided. Significant errors in the spectrometer sensitivity and discrimination can result from improper tuning and calibration of noble gas mass spectrometers

An Intermediate State of the {gamma}-Aminobutyric Acid Transporter GAT1 Revealed by Simultaneous Voltage Clamp and Fluorescence

The rat {gamma}-aminobutyric acid transporter GAT1 expressed in Xenopus oocytes was labeled at Cys74, and at one or more other sites, by tetramethylrhodamine-5-maleimide, without significantly altering GAT1 function. Voltage-jump relaxation analysis showed that fluorescence increased slightly and monotonically with hyperpolarization; the fluorescence at -140 mV was ~0.8% greater than at +60 mV. The time course of the fluorescence relaxations was mostly described by a single exponential with voltage-dependent but history-independent time constants ranging from ~20 ms at +60 mV to ~150 ms at -140 mV. The fluorescence did not saturate at the most negative potentials tested, and the midpoint of the fluorescence–voltage relation was at least 50 mV more negative than the midpoint of the charge–voltage relation previously identified with Na+ binding to GAT1. The presence of {gamma}-aminobutyric acid did not noticeably affect the fluorescence waveforms. The fluorescence signal depended on Na+ concentration with a Hill coefficient approaching 2. Increasing Cl- concentration modestly increased and accelerated the fluorescence relaxations for hyperpolarizing jumps. The fluorescence change was blocked by the GAT1 inhibitor, NO-711. For the W68L mutant of GAT1, the fluorescence relaxations occurred only during jumps to high positive potentials, in agreement with previous suggestions that this mutant is trapped in one conformational state except at these potentials. These observations suggest that the fluorescence signals monitor a novel state of GAT1, intermediate between the E*out and Eout states of Hilgemann, D.W., and C.-C. Lu (1999. J. Gen. Physiol. 114:459–476). Therefore, the study provides verification that conformational changes occur during GAT1 function

Isobar-free neon isotope measurements of flux-fused potential reference minerals on a Helix-MC-Plus^(10K) mass spectrometer

This work presents new analytical techniques for extraction and analysis of neon from a suite of different mineral phases, including quartz, pyroxene, hematite, apatite, zircon, topaz, and fluorite. Neon was quantitatively extracted at 1100 °C from all of these minerals using an in-vacuum lithium borate-flux fusion technique. Evolved neon was purified using a cryogenic method capable of separating Ne from He present in abundances ~8 orders of magnitude higher, typical of samples carrying nucleogenic/radiogenic noble gases. The purified neon was measured on a Helix-MC-Plus^(10K) mass spectrometer that permits isobar-free measurement of all three neon isotopes. When operated at its highest mass resolving power (MRP) of ~10,300, the shoulder representing solely ²²Ne on the low mass-side of the ²²Ne-CO₂⁺² doublet is wide enough to permit measurement of isobar free ²²Ne. Operating in this mode comes with the penalty of a 50% reduction in neon sensitivity. Coupled with a mathematical isobar-stripping method, this approach excludes 99.5% of the CO₂⁺² while still collecting >99% of the ²²Ne beam. Routine edge-centering on the dynamic CO₂⁺² peak prior to introduction of a sample permits rapid and robust relocation of the desired measure point in the mass spectrum. Cosmogenic ²¹Ne and ²²Ne concentrations obtained using these methods on the Cronus-A quartz and Cronus-P pyroxene international reference materials are in excellent agreement with previous work or expectations. Similarly, the concentration of nucleogenic ²¹Ne and ²²Ne in Durango apatite and the CIT hematite standard agree well with previous work. Durango apatite has notable heterogeneity in neon concentrations, consistent with previous observations of heterogeneous He, U and Th concentrations in this apatite. Nucleogenic neon concentrations are also presented for previously unstudied minerals including a Sri Lanka zircon (SLC), a topaz from the Imperial Topaz mine in Brazil (ITP1), and a fluorite (W-90) from New Hampshire. Taken together this set of potential reference minerals and the associated dataset provide a starting point for intercalibration among multiple mineral phases carrying ²¹Ne and ²²Ne of cosmogenic or nucleogenic origin