Accuracy of Fine Needle Aspiration of Pelvic Masses, A Cyto-histological Correlation

Objective: Evaluation of diagnostic efficacy of Fine Needle Aspiration Cytology in differential diagnosis of pelvic masses and correlation between histopathologic and FNA diagnoses. Methods: In this prospective study fifty pelvic masses submitted for pathologic examination, were aspirated by fine needle and analyzed for cytological findings. Cytological findings were categorized as benign, malignant, indeterminate and non- diagnostic. Histological classification was assigned using the guidelines established by the World Health Organization (WHO). A single pathologist evaluated cytological examinations and was blinded to the histological findings of each mass. The same lesions were examined histologically and cytohistological correlation was carried out. Results: Fifty masses from 47 women constituted the study material. The average age of women was 45.7±14.7 years. In Cytological study 32 samples (64%) reported as benign and 9 of them (18%) diagnosed as malignant. Six cases (12%) were non- diagnostic and 3 FNA samples (6%) reported as indeterminate. Histological examination of the masses revealed 30 (60%) benign and 20 malignant lesions. The sensitivity and specificity of FNA cytological study of pelvic masses were 50% and 96%, respectively. The false-positive rate for pelvic masses was 11.1% and the false-negative rate was 25%. Conclusion: Cytological examination of aspirated pelvic masses could not accurately predict pelvic masses histological diagnosis in our university hospital. Since the sensitivity of the technique is not high enough therefore one should not rely on aspiration cytology alone

Trade-off between breast mean glandular dose and image quality in digital and conventional mammogram systems: A multicenter study

Evaluating the patient dose or exposure parameters considering the image quality can improve the chances of accurate diagnosis and reduce the unnecessary exposures from medical devices such as mammography. This study aimed to evaluate digital and conventional mammography machines while considering the trade-off between image quality and mean glandular dose (MGD) using a phantom. In the present study, one full-field digital mammography (FFDM) and two film-screen mammography (FSM) machines were investigated. The MGD values and image quality were assessed using the American College of Radiology (ACR) phantom at various mAs and constant kVp values. The results were obtained and compared with European guidelines. Friedman and Wilcoxon statistical tests were used to show the comparison. The results from the quality control (QC) tests demonstrated that all machines are functioning well. The best image quality in the digital mammography machine was observed at the MGD of 1.8 mGy and 55 mAs. In addition, the two conventional machines had the best image quality regarding the imaging of the ACR phantom at 65 mAs with an MGD of 2.1 mGy. These values were considered as appropriate values for the studied mammography systems. Furthermore, the Friedman test demonstrated that there are significant differences between the measured image quality values obtained from the different machines (p < 0.05), however, according to the Wilcoxon test there were not any significant differences between the conventional machines at various mAs values. Owing to the results, for a medium breast size, the image quality will not be improved with increasing the exposure after a specified MGD corresponds to a certain mAs. It is notable that this value is smaller in digital mammography system at a reasonably low dose