Evaluation of Storage Reallocation and Related Strategies for Optimizing Reservoir System Operations

Statement of the Problem Rapid population and economic growth combined with depleting groundwater reserves are resulting in ever increasing demands on surface water resources in Texas, as well as elsewhere. The climate of the state is characterized by extremes of floods and droughts. Reservoirs are necessary to control and utilize the highly variable streamflow. Due to a number of economic, environmental, institutional, and political considerations, construction of new reservoir projects is much more difficult now than in the past. Consequently, optimizing the beneficial use of existing reservoirs is becoming increasingly more important. Reservoir operation is based on the conflicting objectives of maximizing the amount of water available for conservation purposes and maximizing the amount of empty space available for storing future flood waters to reduce downstream damages. Common practice is to operate a reservoir for either flood control only, conservation only, or a combination of flood control and conservation with separate pools designated for each. The conservation and flood control pools, or vertical zones, in a multipurpose project are fixed by a designated top of conservation (bottom of flood control) pool elevation. Conservation pools may be shared by various purposes, such as water supply, hydroelectric power, and recreation, which involve both complementary and conflicting interactions. Public needs and objectives and numerous factors affecting reservoir operation change over time. An increasing necessity to use limited storage capacity as effectively as possible warrants periodic re-evaluations of operating policies. Reallocation of storage capacity between purposes represents a general strategy for optimizing the beneficial use of limited storage capacity in response to changing needs and conditions. A storage reallocation between flood control and conservation purposes typically involves a permanent or seasonal change in the designated top of conservation pool elevation. Reallocations between conservation purposes can be achieved by various modifications of operating policies. Although given relatively little consideration in the past, storage reallocations will likely be proposed more frequently as demands on limited resources increase. Scope of Study This report documents an investigation of: (1) the potential of storage capacity reallocation and other related modifications in operating policies as management strategies for optimizing the beneficial use of existing reservoirs in Texas and (2) modeling capabilities for formulating and evaluating such changes to operating policies. In general, storage reallocations can involve a variety of types of reservoir use. The present study focused primarily on flood control and water supply. Multiple purpose reservoir operations involving hydroelectric power were also investigated. Both permanent conversion of storage capacity between purposes and seasonal rule curve operations were addressed. Buffer pool operations were also considered. Multiple reservoir system operation was a major emphasis of the study. The literature was reviewed and several reservoir management agencies contacted to (1) identify experiences in studying and/or implementing storage reallocations and (2) evaluate the state-of-the-art of associated modeling and analysis capabilities. The feasibility of seasonal rule curve operation depends upon the seasonal characteristics of the various factors affecting reservoir operation. Precipitation, streamflow, reservoir evaporation, water demands, and reservoir storage content data for Texas were analyzed to identify seasonal characteristics. A 12-reservoir system operated by the U.S. Army Corps of Engineers and Brazos River Authority provided a case study for evaluating the potential for storage reallocations and related operating strategies. This system, located in the Brazos River Basin, is considered representative of major reservoirs in Texas. The existing operating policies and possible modifications were investigated. The case study includes (1) flood control storage frequency and conservation drawdown frequency analyses based on the results of monthly hydrologic period-of-record simulations of reservoir system operations and (2) firm yield and reliability analyses. The generalized computer programs HEC-3, HEC-5, STATS, and MOSS-IV, and several utility software packages were used in the modeling study. Simulation of reservoir system operations was based on an 85-year sequence of monthly hydrologic data. The case study provides a preliminary assessment of the viability of permanent storage conversions and/or adoption of seasonal rule curve operations as potential reservoir management strategies. The objective is to evaluate storage reallocation potentialities in general, not develop detailed reallocation plans. The case study is basically a reconnaissance-level hydrologic analysis of reservoir operations. The monthly period-of-record simulations provide a reasonably precise analysis of water supply considerations. However, the daily hydrologic data required for detailed analysis of flood control operations were not included in the study. Reallocation of reservoir storage capacity involves complex institutional, financial, economic, legal, political, and technical considerations not addressed in the case study. However, the hydrologic analyses provide a good starting point for determining what types of reallocation strategies and modeling approaches might be potentially effective and whether more detailed studies are worthwhile. Organization of the Report Chapter 2 is a general discussion of reservoir operation and institutional and technical aspects of storage reallocation and a review of reallocations which have been implemented or proposed throughout the nation. Chapter 3 addresses the seasonality of the hydrologic factors pertinent to seasonal rule curve operation in Texas. Chapter 4 reviews state-of-the-art modeling capabilities and describes the computer models adopted for use in the case study. The Brazos River Basin case study is presented in chapters 5 through 8. Study results are summarized, and conclusions are presented in chapter 9

Do we understand the incompressibility of neutron-rich matter?

The ``breathing mode'' of neutron-rich nuclei is our window into the incompressibility of neutron-rich matter. After much confusion on the interpretation of the experimental data, consistency was finally reached between different models that predicted both the distribution of isoscalar monopole strength in finite nuclei and the compression modulus of infinite matter. However, a very recent experiment on the Tin isotopes at the Research Center for Nuclear Physics(RCNP) in Japan has again muddled the waters. Self-consistent models that were successful in reproducing the energy of the giant monopole resonance (GMR) in nuclei with various nucleon asymmetries (such as 90Zr, 144Sm, and 208Pb) overestimate the GMR energies in the Tin isotopes. As important, the discrepancy between theory and experiment appears to grow with neutron excess. This is particularly problematic as models artificially tuned to reproduce the rapid softening of the GMR in the Tin isotopes become inconsistent with the behavior of dilute neutron matter. Thus, we regard the question of ``why is Tin so soft?'' as an important open problem in nuclear structure.Comment: 12 pages, 3 figures, and 1 table. Submitted to the "Focus issue on Open Problems in Nuclear Structure", Journal of Physics

Development of a Standard Test Scenario to Evaluate the Effectiveness of Portable Fire Extinguishers on Lithium-ion Battery Fires

Many sources of fuel are present aboard current spacecraft, with one especially hazardous source of stored energy: lithium ion batteries. Lithium ion batteries are a very hazardous form of fuel due to their self-sustaining combustion once ignited, for example, by an external heat source. Batteries can become extremely energetic fire sources due to their high density electrochemical energy content that may, under duress, be violently converted to thermal energy and fire in the form of a thermal runaway. Currently, lithium ion batteries are the preferred types of batteries aboard international spacecraft and therefore are routinely installed, collectively forming a potentially devastating fire threat to a spacecraft and its crew. Currently NASA is developing a fine water mist portable fire extinguisher for future use on international spacecraft. As its development ensues, a need for the standard evaluation of various types of fire extinguishers against this potential threat is required to provide an unbiased means of comparing between fire extinguisher technologies and ranking them based on performance

OA031-02. Regulatory T cells inhibit CD8 T cell proliferation in HIV-1 infection through CD39/adenosine pathway

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Pygmies, Giants, and Skins

Understanding the equation of state (EOS) of neutron-rich matter is a central goal of nuclear physics that cuts across a variety of disciplines. Indeed, the limits of nuclear existence, the collision of energetic heavy ions, the structure of neutron stars, and the dynamics of core-collapse supernova all depend critically on the nuclear-matter EOS. In this contribution I focus on the EOS of cold baryonic matter with special emphasis on its impact on the structure, dynamics, and composition of neutron stars. In particular, I discuss how laboratory experiments on neutron skins as well as on Pygmy and Giant resonances can help us elucidate the structure of these fascinating objects.Comment: Invited Talk given at the 11th International Conference on Nucleus-Nucleus Collisions (NN2012), San Antonio, Texas, USA, May 27-June 1, 2012. To appear in the NN2012 Proceedings in Journal of Physics: Conference Series (JPCS

Nonuniform Neutron-Rich Matter and Coherent Neutrino Scattering

Nonuniform neutron-rich matter present in both core-collapse supernovae and neutron-star crusts is described in terms of a semiclassical model that reproduces nuclear-matter properties and includes long-range Coulomb interactions. The neutron-neutron correlation function and the corresponding static structure factor are calculated from molecular dynamics simulations involving 40,000 to 100,000 nucleons. The static structure factor describes coherent neutrino scattering which is expected to dominate the neutrino opacity. At low momentum transfers the static structure factor is found to be small because of ion screening. In contrast, at intermediate momentum transfers the static structure factor displays a large peak due to coherent scattering from all the neutrons in a cluster. This peak moves to higher momentum transfers and decreases in amplitude as the density increases. A large static structure factor at zero momentum transfer, indicative of large density fluctuations during a first-order phase transition, may increase the neutrino opacity. However, no evidence of such an increase has been found. Therefore, it is unlikely that the system undergoes a simple first-order phase transition. It is found that corrections to the commonly used single heavy nucleus approximation first appear at a density of the order of $10^{13}$ g/cm$^3$ and increase rapidly with increasing density. Thus, neutrino opacities are overestimated in the single heavy nucleus approximation relative to the complete molecular dynamics simulations.Comment: 17 pages, 23 included ps figure

Structure and Magnetism of well-defined cobalt nanoparticles embedded in a niobium matrix

Our recent studies on Co-clusters embedded in various matrices reveal that the co-deposition technique (simultaneous deposition of two beams : one for the pre-formed clusters and one for the matrix atoms) is a powerful tool to prepare magnetic nanostructures with any couple of materials even though they are miscible. We study, both sharply related, structure and magnetism of the Co/Nb system. Because such a heterogeneous system needs to be described at different scales, we used microscopic and macroscopic techniques but also local selective absorption ones. We conclude that our clusters are 3 nm diameter f.c.c truncated octahedrons with a pure cobalt core and a solid solution between Co and Nb located at the interface which could be responsible for the magnetically inactive monolayers we found. The use of a very diluted Co/Nb film, further lithographed, would allow us to achieve a pattern of microsquid devices in view to study the magnetic dynamics of a single-Co cluster.Comment: 7 TeX pages, 9 Postscript figures, detailed heading adde

PTHrP and SPARC expressions in human colorectal cancer: An in silico analysis

PTHrP is a paraneoplastic factor involved in the progression and theacquisition of the aggressive behavior of different types of tumors. Employing in vitroand in vivo models of colorectal cancer (CRC), our research group observed thatPTHrP promotes cell survival, proliferation, migration, angiogenesis, epithelial tomesenchymal transition (EMT) program, cancer stem cell (CSC) phenotype, andchemoresistance through different signaling pathways. Recently, in HCT116 cellsderived from CRC we found that PTHrP acts increasing SPARC protein expression, arelevant protein involved in CRC progression. Moreover, SPARC treatment on HCT116cells potentiated PTHrP effects. In vivo model, PTHrP also increased SPARC expression. Based on these findings, the aim of this work is explore the clinical relevance ofPTHrP and SPARC tumor expression in human CRC using in silico analysis.Methods: Cytoscape 3.8.2 stringApp was employed to visualize molecular networksfrom the STRING database related to CRC, and proteins associated with prognosticfactors were selected to analysis. Using STRING Enrichment App, the proteins networks (PN) merged were compared to establish enrichment. Finally, in silico tool andonline data sets (GEPIA2 and STRING 11.0) were used to explore the association ofPTHrP and SPARC and their prognostic value in 362 CRC human samples.Results: In GEPIA2 database, a significant correlation between the expressions ofPTHrP and SPARC in CRC was observed (p-value¼0.01). Also, SPARC expression washigher in CRC respect to colorectal normal samples (p-value¼0.01). In the same way,SPARC expression was significantly higher in CRC advanced than in early disease.Employing STRING 11.0 database, we observed a strong association between PTHrPand several oncogenic markers (CDH2, CD44, VIM, among others) that previouslywere evaluated in vitro by us linked through SPARC with a Protein-Protein interactionenrichment (p-value 0.95). This PN was merged with the PN obtained from the search?colorectal cancer? with a high disease score (SD> 3.2). From this analysis, VEGFA wasemerged as a central nexus between PTHrP and SPARC proteins. Finally, GEPIA2 wasused to evaluate the survival rate in CRC patients that express PTHrP and/or SPARC.No significant impact in overall survival was found taken account high or lowexpression of each protein.Conclusions: In CRC tumor samples, a strong relationship between PTHrP and SPARCexpression was found, suggesting that both proteins could be involved in the progression of the disease. Despite VEGFA was also associated with PTHrP/SPARC, morestudies are necessary to evaluate their clinical relevancy.Fil: Carriere, Pedro Matias. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; ArgentinaFil: Novoa Díaz, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; ArgentinaFil: López Moncada, Fernanda. Universidad de Chile. Facultad de Medicina.; ChileFil: Zwenger, A.. Centro de Estudios Clinicos SAGA; ChileFil: Contreras, H.. Universidad de Chile. Facultad de Medicina.; ChileFil: Calvo, Natalia Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; ArgentinaFil: Gentili, Claudia Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Ciencias Biológicas y Biomédicas del Sur. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia. Instituto de Ciencias Biológicas y Biomédicas del Sur; ArgentinaESMO World Congress on Gastrointestinal Cancer 2021Modalidad virtualEstados UnidosEuropean Society for Medical Oncolog