359 research outputs found
Minority Student Perceptions of Professional Pscyhology Application Packets: A Qualitative Study
This article reports the results of a qualitative study designed to determine issues salient in Black and Hispanic American students\u27 review and evaluation of program-application packets in professional psychology. The study served as an extension to the Yoshida et al. (1989) quantitative investigation. Students interested in pursuing doctoral studies in counseling or school psychology (N = 22) served as the sample. The qualitative methodology incorporated a think-aloud procedure and semistructured interviews. A theme analysis of transcribed interviews identified both major and minor themes central to participants\u27 evaluation of the packets. Major themes included financial aid, program requirements and course descriptions, demography of the student body, and the quality and clarity of application material. Specific suggestions on developing an application packet to send to inquiring prospective students are put forth. It is recommended that such a packet could serve as a costeffective minority-recruitment strategy
Prospective Minority Students\u27 Perceptions of Application Packets for Professional Psychology Programs: A Qualitative Study
This article reports the results of a qualitative study designed to determine issues salient in Black and Hispanic American students\u27 review and evaluation of program-application packets in professional psychology. The study served as an extension to the Yoshida et al. (1989) quantitative investigation. Students interested in pursuing doctoral studies in counseling or school psychology (N = 22) served as the sample. The qualitative methodology incorporated a think-aloud procedure and semistructured interviews. A theme analysis of transcribed interviews identified both major and minor themes central to participants\u27 evaluation of the packets. Major themes included financial aid, program requirements and course descriptions, demography of the student body, and the quality and clarity of application material. Specific suggestions on developing an application packet to send to inquiring prospective students are put forth. It is recommended that such a packet could serve as a cost-effective minority-recruitment strategy
Daughters\u27 Perspectives on Maternal Substance Abuse: Pledge to Be a Different Kind of Mother
The purpose of this grounded theory (Strauss & Corbin, 1998) study was to explore the experiences of racially and culturally diverse young mothers whose own mothers abused substances two decades ago when substance abuse peaked in inner city, urban neighborhoods in the United States and to identify the factors that have influenced how they parent their own children today. Semi-structured interviews were conducted with ten drug-free mothers who report having been raised by a mother who was addicted to drugs, primarily crack cocaine during their childhoods. The emergent grounded theory is that exposure to maternal substance abuse has a significant and unique impact on female children throughout their lifespan, with particular emphasis at the onset of motherhood. Among the goals the young mothers expressed is that they wanted to be there for their children, protect their daughters from sexual abuse, and raise sons who do not abuse women
An Embankment on Soft Clays with Sand Drains Numerical Characterization of the Parameters from In-situ Measurements
The deformation parameters of a soft lacustrine deposit, with vertical sand drains, are evaluated by means of field measurements obtained during and after the construction of a railway embankment. The geotechnical system, modelled as linearly elastic and in plane strain, is analyzed by means of the finite element method and the estimation problem is solved adopting a Bayesian approach. The experimental data, the a priori estimation of the parameters and their uncertainties are considered in the back-analysis. The results provide the optimal values of the parameters, a measure of their uncertainties and, consequently, an index of the effectiveness of the field measurement program
Ride analysis tools for passenger cars: objective and subjective evaluation techniques and correlation processes–a review
In passenger cars, the ride characteristics are fundamental to the driver and passenger engagement, as they define the comfort and road holding performance. Therefore, the methods and tools to assess ride quality are of significant interest to the vehicle dynamics specialists, and are an important part of the internal know-how of each car maker and Tier 1 supplier, which is often kept confidential. Unfortunately, the available literature does not include a comprehensive survey on the evaluation of the objective and subjective aspects related to ride, and their correlation. This review targets the gap, and deals with: (i) the available tools and techniques to objectively assess primary and secondary ride, including typical manoeuvres, road profiles, required vehicle instrumentation, and key performance indicators (KPIs); (ii) the subjective attributes and their categorisation; (iii) the approaches and mathematical models to correlate the objective KPIs with the subjective evaluation; and (iv) future trends. The know-how of the authors on the ride assessment of high-performance passenger cars will also be used to cover the aspects that are currently overlooked by the available literature and standards. In summary, the manuscript provides the interested reader with useful guidance on the procedures to perform ride quality analyses
Effect of n-acetylcysteine administration on 30-day mortality in critically ill patients with septic shock caused by carbapenem-resistant klebsiella pneumoniae and acinetobacter baumannii. A retrospective case-control study
Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) and Acinetobacter baumannii (CR-Ab) represent important cause of severe infections in intensive care unit (ICU) patients. N-Acetylcysteine (NAC) is a mucolytic agent with antioxidant and anti-inflammatory properties, showing also in-vitro antibacterial activity. Aim was to evaluate the effect on 30-day mortality of the addition of intravenous NAC to antibiotics in ICU patients with CR-Kp or CR-Ab septic shock. A retrospective, observational case:control study (1:2) in patients with septic shock caused by CR-Kp or CR-Ab hospitalized in two different ICUs was conducted. Cases included patients receiving NAC plus antimicrobials, controls included patients not receiving NAC. Cases and controls were matched for age, SAPS II, causative agent and source of infection. No differences in age, sex, SAPS II score or time to initiate definitive therapy were observed between cases and controls. Pneumonia and bacteremia were the leading infections. Overall, mortality was 48.9% (33.3% vs. 56.7% in cases and controls, p = 0.05). Independent risk factors for mortality were not receiving NAC (p = 0.002) and CR-Ab (p = 0.034) whereas therapy with two in-vitro active antibiotics (p = 0.014) and time to initial definite therapy (p = 0.026) were protective. NAC plus antibiotics might reduce the 30-day mortality rate in ICU patients with CR-Kp and CR-Ab septic shock
Anticholinergic drug burden tools/scales and adverse outcomes in different clinical settings: a systematic review of reviews
Background: Cumulative anticholinergic exposure (anticholinergic burden) has been linked to a number of adverse outcomes. To conduct research in this area, an agreed approach to describing anticholinergic burden is needed.
Objective: This review set out to identify anticholinergic burden scales, to describe their rationale, the settings in which they have been used and the outcomes associated with them.
Methods: A search was performed using the Healthcare Databases Advanced Search of MEDLINE, EMBASE, Cochrane, CINAHL and PsycINFO from inception to October 2016 to identify systematic reviews describing anticholinergic burden scales or tools. Abstracts and titles were reviewed to determine eligibility for review with eligible articles read in full. The final selection of reviews was critically appraised using the ROBIS tool and pre-defined data were extracted; the primary data of interest were the anticholinergic burden scales or tools used.
Results: Five reviews were identified for analysis containing a total of 62 original articles. Eighteen anticholinergic burden scales or tools were identified with variation in their derivation, content and how they quantified the anticholinergic activity of medications. The Drug Burden Index was the most commonly used scale or tool in community and database studies, while the Anticholinergic Risk Scale was used more frequently in care homes and hospital settings. The association between anticholinergic burden and clinical outcomes varied by index and study. Falls and hospitalisation were consistently found to be associated with anticholinergic burden. Mortality, delirium, physical function and cognition were not consistently associated.
Conclusions: Anticholinergic burden scales vary in their rationale, use and association with outcomes. This review showed that the concept of anticholinergic burden has been variably defined and inconsistently described using a number of indices with different content and scoring. The association between adverse outcomes and anticholinergic burden varies between scores and has not been conclusively established
MBGEM: a stack of borated GEM detector for high efficiency thermal neutron detection
A new position-sensitive thermal neutron detector based on boron-coated converters has been developed as an alternative to today’s standard 3He -based technology for application to thermal neutron scattering. The key elements of the development are the boron-coated GEM foils (Sauli in Nucl Instrum Methods Phys Res Sect A Accel Spectrom Detect Assoc Equip 386:531, 1997) that are used as a multi-layer neutron converter via the 10B (n, α) 7Li reaction together with an efficient collection of the produced secondary electrons. This paper reports the test performed on a 3 layers converter prototype coupled to a GEMPix detector (Murtas in Radiat Meas 138:106421, 2020), carried out in order to study the possibility to produce a large-scale multi-layer neutron detector capable to reach high detection efficiency with high spatial resolution and able to sustain the high neutron flux expected in the new neutron spallation source under development like the ESS
Clinical course of Coronavirus Disease-19 in patients with haematological malignancies is characterized by a longer time to respiratory deterioration compared to non-haematological ones: results from a case-control study
Background We evaluated clinical features and risk factors for mortality in patients with haematological malignancies and COVID-19. Methods Retrospective, case-control (1:3) study in hospitalized patients with COVID-19. Cases were patients with haematological malignancies and COVID-19, controls had COVID-19 without haematological malignancies. Patients were matched for sex, age and time of hospitalization. Results Overall, 66 cases and 198 controls were included in the study. Cases had higher prior corticosteroid use, infection rates, thrombocytopenia and neutropenia and more likely received corticosteroids and antibiotics than controls. Cases had higher respiratory deterioration than controls (78.7% vs 65.5%, p = 0.04). Notably, 29% of cases developed respiratory worsening > 10 days after hospital admission, compared to only 5% in controls. Intensive Care Unit admission and mortality were higher in cases than in controls (27% vs 8%, p = 0.002, and 35% vs 10%, p < 0.001). At multivariable analysis, having haematological malignancy [OR4.76, p < 0.001], chronic corticosteroid therapy [OR3.65, p = 0.004], prior infections [OR57.7, p = 0.006], thrombocytopenia [OR3.03, p < 0.001] and neutropenia [OR31.1, p = 0.001], low albumin levels [OR3.1, p = 0.001] and >= 10 days from hospital admission to respiratory worsening [OR3.3, p = 0.002] were independently associated with mortality. In cases, neutropenia [OR3.1, p < 0.001], prior infections [OR7.7, p < 0.001], >= 10 days to respiratory worsening [OR4.1, p < 0.001], multiple myeloma [OR1.5, p = 0.044], the variation of the CT lung score during hospitalization [OR2.6, p = 0.006] and active treatment [OR 4.4, p < 0.001] all were associated with a worse outcome. Conclusion An underlying haematological malignancy was associated with a worse clinical outcome in COVID-19 patients. A prolonged clinical monitoring is needed, since respiratory worsening may occur later during hospitalization
Operation of a 250μm-thick SiC detector with DT neutrons at high temperatures
The Silicon Carbide detector (SiC) is an object of research as an alternative to diamond detectors for fast neutron detection and spectrometry where harsh environments are an issue, like in Tokamaks. Since future breeding blankets mock-ups will feature temperatures up to 550 °C, diamond detectors were characterized in the past, finding limitations in their functionality at high temperatures. This paper expands on the previous work by proving the detection of fast neutrons with good detection parameters of a 250 μm-thick 4 H-SiC detector prototype at temperatures up to 250 °C, highlighting the detector's excellent resilience to temperature. The experiment is conducted with instrumentation similar to the one used in the past with diamond detectors, using as source of irradiation the Frascati Neutron Generator (FNG) in ENEA, which is accelerator driven neutron source based on deuterium-tritium (DT) fusion reaction
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