V-06.02: Laparoscopic radical cystoprostatic adenectomy

Introduction: We hereby present a new laparoscopic prostate-preserving cystectomy technique that aims at reducing sexual dysfunction and urinary incontinence in comparison with the conventional technique of laparoscopic radical cystoprostatectom

Critical States Embedded in the Continuum

We introduce a class of critical states which are embedded in the continuum (CSC) of one-dimensional optical waveguide array with one non-Hermitian defect. These states are at the verge of being fractal and have real propagation constant. They emerge at a phase transition which is driven by the imaginary refractive index of the defect waveguide and it is accompanied by a mode segregation which reveals analogies with the Dicke super -radiance. Below this point the states are extended while above they evolve to exponentially localized modes. An addition of a background gain or loss can turn these localized states to bound states in the continuum.Comment: 4.5 pages, 3 figures, 1 page of supplementary material including one figur

Cholinesterase Enzymes Inhibitors from the Leaves of Rauvolfia Reflexa and Their Molecular Docking Study

molecule

The Effect of G-ORS Along With Rice Soup in the Treatment of Acute Diarrhea in Children: A Single-Blind Randomized Controlled Trial

Background: The world health organization guidelines for treatment of diarrhea in children emphasize on continued feeding together with prescription of oral rehydration solution (ORS) and supplementary zinc therapy. However, conflicting viewpoints exist regarding the optimal diet and dietary ingredients for children with diarrhea. Moreover, few studies have investigated the effect of rice soup along with ORS in the treatment of this disease. Objectives: This study aimed to explore effects of simultaneous taking of glucose oral rehydration solution (G-ORS) and rice soup in the treatment of acute diarrhea in 8 to 24-month-old children. Patients and Methods: This single-blind controlled clinical trial was conducted in the pediatric ward of 22nd of Bahman hospital, Gonabad, Iran between June 2013 and February 2014. Forty children aged 8-24 months with acute diarrhea were randomly assigned into an intervention group (G-ORS plus rice soup group) comprising 20 babies and a control group (G-ORS) of 20 children based on balanced blocking randomization. The variables under investigation were diarrhea duration, patient hospitalization, need for intravenous (IV) fluids and stool output frequency. Data was analyzed using independent samples t and chi-square test. Results: At the end of study, the time for treating acute watery diarrhea in the intervention and control groups were 21.10 ± 8.81 and 34.55 ± 5.82 hours (P < 0.001) and hospital stay were 34.05 ± 6.62 and 40.20 ± 6.32 hours (P = 0.005). Moreover, stool output frequency were 4.20 ± 0.95 and 8.00 ± 1.37 (P < 0.001) in the first 24 hours, and 2.18 ± 0.60 and 2.80 ± 0.76 (P = 0.03) in the second 24 hours of treatment in intervention and control groups, respectively. Conclusions: Rice soup regimen was highly effective and inexpensive in the treatment of acute diarrhea in children. Thus, in addition to the common treatment by G-ORS, rice soup can be consumed simultaneously with G-ORS

Simulating and Modeling the Signal Attenuation of Wireless Local Area Network for Indoor Positioning

Location is a key filter for mobile services, including navigation or advertising. However, positioning and localization inside buildings and in indoor spaces, where users spend most of their time and where the signals of the most widely-used positioning system, i.e. Global Navigation Satellite Systems such as GPS (Global Positioning System), are not available, can be challenging. In this regard, Wireless Local Area Networks (WLAN), e.g. Wi-Fi, can be used for positioning purposes by using a WLAN-enabled device, e.g. a smartphone, to measure and match the Received Signal Strength (RSS) of a signal broadcast by an access point. The challenges of this approach are that accurate maps of RSS are required, and that measuring RSS can be affected by many factors, including the dynamics of the environment and the orientation and type of a device. This paper provides a path-loss model to produce RSS maps automatically from floor plans and introduces an agent-based simulation approach to investigate different positioning methods. This provides a pathway to reduce the time and effort associated with WLAN positioning research

Simulating and Modeling the Signal Attenuation of Wireless Local Area Network for Indoor Positioning

Location is a key filter for mobile services, including navigation or advertising. However, positioning and localization inside buildings and in indoor spaces, where users spend most of their time and where the signals of the most widely-used positioning system, i.e. Global Navigation Satellite Systems such as GPS (Global Positioning System), are not available, can be challenging. In this regard, Wireless Local Area Networks (WLAN), e.g. Wi-Fi, can be used for positioning purposes by using a WLAN-enabled device, e.g. a smartphone, to measure and match the Received Signal Strength (RSS) of a signal broadcast by an access point. The challenges of this approach are that accurate maps of RSS are required, and that measuring RSS can be affected by many factors, including the dynamics of the environment and the orientation and type of a device. This paper provides a path-loss model to produce RSS maps automatically from floor plans and introduces an agent-based simulation approach to investigate different positioning methods. This provides a pathway to reduce the time and effort associated with WLAN positioning research

Tubulin nucleotide status controls Sas-4-dependent pericentriolar material recruitment

Regulated centrosome biogenesis is required for accurate cell division and for maintaining genome integrity1. Centrosomes consist of a centriole pair surrounded by a protein network known as pericentriolar material (PCM)1. PCM assembly is a tightly regulated, critical step that determines a centrosome’s size and capability2–4. Here, we report a role for tubulin in regulating PCM recruitment via the conserved centrosomal protein Sas-4. Tubulin directly binds to Sas-4; together they are components of cytoplasmic complexes of centrosomal proteins5,6. A Sas-4 mutant, which cannot bind tubulin, enhances centrosomal protein complex formation and has abnormally large centrosomes with excessive activity. These suggest that tubulin negatively regulates PCM recruitment. Whereas tubulin-GTP prevents Sas-4 from forming protein complexes, tubulin-GDP promotes it. Thus, tubulin’s regulation of PCM recruitment depends on its GTP/GDP-bound state. These results identify a role for tubulin in regulating PCM recruitment independent of its well-known role as a building block of microtubules7. Based on its guanine bound state, tubulin can act as a molecular switch in PCM recruitment

Human health risk assessment due to ambient PM10 and SO2 by an air quality modeling technique

Exposure to air pollutants may be an important environmental risk factor for human health. The main objective of this study was to assess the health impacts of exposure to particulate matter of aerodynamic diameter <= 10 mu g (PM10) and to sulfur dioxide (SO2) using the AirQ2.2.3 software developed by the WHO European Center for Environment and Health. Daily concentrations of PM10 and SO2 were used to assess the health effects. With regard to the mortality, the results showed that 3.9 (95 CI: 3.3-4.5) of total, 4.2 (95 CI: 2.7-9.05) of cardiovascular, and 6.2 (95 CI: 4.2-16.9) of respiratory mortality were related to PM10 concentrations above 10 mu g/m(3), respectively. In addition, 1.7 (95 CI: 1.3-2.06) of total, 3.4 (95 CI: 0.78-5.0) of cardiovascular, and 2 (95 CI: 2.5-5.7) of respiratory death were attributed to SO2 levels higher than 10 mu g/m(3), respectively. Given these findings, urgent policy decisions are needed to reduce the death caused by air pollution, and better quantification studies are recommended. (C) 2017 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved