Hydrogen emissions from the hydrogen value chain-emissions profile and impact to global warming

Future energy systems could rely on hydrogen (H2) to achieve decarbonisation and net-zero goals. In a similar energy landscape to natural gas, H2 emissions occur along the supply chain. It has been studied how current gas infrastructure can support H2, but there is little known about how H2 emissions affect global warming as an indirect greenhouse gas. In this work, we have estimated for the first time the potential emission profiles (g CO2eq/MJ H2,HHV) of H2 supply chains, and found that the emission rates of H2 from H2 supply chains and methane from natural gas supply are comparable, but the impact on global warming is much lower based on current estimates. This study also demonstrates the critical importance of establishing mobile H2 emission monitoring and reducing the uncertainty of short-lived H2 climate forcing so as to clearly address H2 emissions for net-zero strategies

Profile of cytokines, growth factors and chemokines during attacks of FMF

PubMe

Methane emissions along biomethane and biogas supply chains are underestimated

Although natural gas generates lower CO2 emissions, gas extraction, processing, and distribution all release methane, which has a greater global warming potential than CO2. Biomethane and biogas that use organic wastes as a feedstock have emerged as alternatives to natural gas, with lower carbon and methane emissions. However, the extent to which methane is still emitted at various stages along biogas and biomethane supply chains remains unclear. Here, we adopt a Monte Carlo approach to systematically synthesize the distribution of methane emissions at each key biomethane and biogas supply chain stage using data collected from the existing literature. We show that the top 5% of emitters are responsible for 62% of emissions. Methane emissions could be more than two times of greater than previously estimated, with the digestate handling stage responsible for the majority of methane released. To ensure the climate benefits of biomethane and biogas production, effective methane-mitigation strategies must be designed and deployed at each supply chain stage

MEFV mutations in systemic JIA

Background: Systemic form of juvenile idiopathic arthritis (JIA) is regarded as an autoinflammatory disease. Certain genetic polymorphisms in genes coding inflammatory proteins have been associated with the disease. On the other hand mutations of the MEFV gene cause a monogenic autoinflammatory disease, Familial Mediterranean Fever (FMF). In a previous study in adult rheumatoid arthritis 3 out of the 25 British patients who developed secondary amyloidosis had a mutation/polymorphism in the MEFV gene. Aim: To analyse whether mutaions in the MEFV gene had an association with systemic JIA. Patients and methods: MEFV mutations were screened in a total of 32 systemic JIA patients. All had been classified as systemic JIA according to the Durban JIA criteria. None had disease characteristics that met the Tel Hashomer criteria for the diagnosis of FMF. Results: 2 carrier for M694V and two patients who were homozygote for MEFV mutations. Both of these patients were among the most severe patients in the group. One had an excellent response to etanercept whereas the other was resistant to anti-TNF and other conventional treatments and had only a partial response to thalidomide. Although the number of severe mutations were increased in this small group of patients with systemic JIA the difference with the Turkish population did not reach statistical significance, but the disease causing mutation (M694V) was significantly high in the patients with systemic JIA(p = 0.02). Conclusion: However, the severe disease course in the aforementioned patients suggest that MEFV mutations may be a modifying genetic factor in systemic JIA.PubMe

Assessment of children presenting with rheumatic complaints to a tertiary center in Turkey: differences in an Eastern Mediterranean population

PubMe

A safe protocol for tuberculin test assessment in a country where BCG vaccination is mandatory

PubMe

Musculoskeletal sonography in juvenile systemic lupus erythematosus

PubMedWo

Methane Mitigation:Methods to Reduce Emissions, on the Path to the Paris Agreement

The atmospheric methane burden is increasing rapidly, contrary to pathways compatible with the goals of the 2015 United Nations Framework Convention on Climate Change Paris Agreement. Urgent action is required to bring methane back to a pathway more in line with the Paris goals. Emission reduction from “tractable” (easier to mitigate) anthropogenic sources such as the fossil fuel industries and landfills is being much facilitated by technical advances in the past decade, which have radically improved our ability to locate, identify, quantify, and reduce emissions. Measures to reduce emissions from “intractable” (harder to mitigate) anthropogenic sources such as agriculture and biomass burning have received less attention and are also becoming more feasible, including removal from elevated-methane ambient air near to sources. The wider effort to use microbiological and dietary intervention to reduce emissions from cattle (and humans) is not addressed in detail in this essentially geophysical review. Though they cannot replace the need to reach “net-zero” emissions of CO2, significant reductions in the methane burden will ease the timescales needed to reach required CO2 reduction targets for any particular future temperature limit. There is no single magic bullet, but implementation of a wide array of mitigation and emission reduction strategies could substantially cut the global methane burden, at a cost that is relatively low compared to the parallel and necessary measures to reduce CO2, and thereby reduce the atmospheric methane burden back toward pathways consistent with the goals of the Paris Agreement