Enabling scalability by partitioning virtual environments using frontier sets

We present a class of partitioning scheme that we have called frontier sets. Frontier sets build on the notion of a potentially visible set (PVS). In a PVS, a world is subdivided into cells and for each cell all the other cells that can be seen are computed. In contrast, a frontier set considers pairs of cells, A and B. For each pair, it lists two sets of cells (two frontiers), FAB and FBA. By definition, from no cell in FAB is any cell in FBA visible and vice versa. Our initial use of frontier sets has been to enable scalability in distributed networking. This is possible because, for example, if at time t0 Player1 is in cell A and Player2 is in cell B, as long as they stay in their respective frontiers, they do not need to send update information to each other. In this paper we describe two strategies for building frontier sets. Both strategies are dynamic and compute frontiers only as necessary at runtime. The first is distance-based frontiers. This strategy requires precomputation of an enhanced potentially visible set. The second is greedy frontiers. This strategy is more expensive to compute at runtime, however it leads to larger and thus more efficient frontiers. Network simulations using code based on the Quake II engine show that frontiers have significant promise and may allow a new class of scalable peer-to-peer game infrastructures to emerge

Subjective Wellbeing, Health and Ageing

Life satisfaction dips around middle age and rises in older age in high-income, English-speaking countries, but that is not a universal pattern, according to a new report. In contrast, residents of other regions -- such as the former Soviet Union, Eastern Europe, Latin America and sub-Saharan Africa -- grow increasingly less satisfied as they age. The study -- conducted by researchers from Princeton University's Woodrow Wilson School of Public and International Affairs, Stony Brook University and University College London -- highlights how residents of different regions across the world experience varying life-satisfaction levels and emotions as they age

Combined Solar System and rotation curve constraints on MOND

The Modified Newtonian Dynamics (MOND) paradigm generically predicts that the external gravitational field in which a system is embedded can produce effects on its internal dynamics. In this communication, we first show that this External Field Effect can significantly improve some galactic rotation curves fits by decreasing the predicted velocities of the external part of the rotation curves. In modified gravity versions of MOND, this External Field Effect also appears in the Solar System and leads to a very good way to constrain the transition function of the theory. A combined analysis of the galactic rotation curves and Solar System constraints (provided by the Cassini spacecraft) rules out several classes of popular MOND transition functions, but leaves others viable. Moreover, we show that LISA Pathfinder will not be able to improve the current constraints on these still viable transition functions.Comment: 13 pages, 7 figures, accepted for publication in MNRA

UV-induced fragmentation of Cajal bodies

The morphology and composition of subnuclear organelles, such as Cajal bodies (CBs), nucleoli, and other nuclear bodies, is dynamic and can change in response to a variety of cell stimuli, including stress. We show that UV-C irradiation disrupts CBs and alters the distribution of a specific subset of CB components. The effect of UV-C on CBs differs from previously reported effects of transcription inhibitors. We demonstrate that the mechanism underlying the response of CBs to UV-C is mediated, at least in part, by PA28γ (proteasome activator subunit γ). The presence of PA28γ in coilin-containing complexes is increased by UV-C. Overexpression of PA28γ, in the absence of UV-C treatment, provokes a similar redistribution of the same subset of CB components that respond to UV-C. RNA interference–mediated knockdown of PA28γ attenuates the nuclear disruption caused by UV-C. These data demonstrate that CBs are specific nuclear targets of cellular stress-response pathways and identify PA28γ as a novel regulator of CB integrity