New optical telescope projects at Devasthal Observatory

Devasthal, located in the Kumaun region of Himalayas is emerging as one of the best optical astronomy site in the continent. The minimum recorded ground level atmospheric seeing at the site is 0.6 arcsec with median value at 1.1 arcsec. Currently, a 1.3-m fast (f/4) wide field-of-view (66 arcmin) optical telescope is operating at the site. In near future, a 4-m liquid mirror telescope in collaboration with Belgium and Canada, and a 3.6-m optical telescope in collaboration with Belgium are expected to be installed in 2013. The telescopes will be operated by Aryabhatta Research Institute of Observational Sciences. The first instruments on the 3.6-m telescope will be in-house designed and assembled faint object spectrograph and camera. The second generation instruments will be including a large field-of-view optical imager, high resolution optical spectrograph, integral field unit and an optical near-infrared spectrograph. The 1.3-m telescope is primarily used for wide field photometry imaging while the liquid mirror telescope will see a time bound operation to image half a degree wide strip in the galactic plane. There will be an aluminizing plant at the site to coat mirrors of sizes up to 3.7 m. The Devasthal Observatory and its geographical importance in between major astronomical observatories makes it important for time critical observations requiring continuous monitoring of variable and transient objects from ground based observatories. The site characteristics, its expansions plans and first results from the existing telescope are presented.Comment: Invited paper, 12 pages, SPIE Conference, July 201

Plasmodium Vivax Associated Myocarditis

Plasmodium infection in human beings is often associated with complications. Complications such as cerebral malaria, acute respiratory distress syndrome, acute kidney injury and cardiac complications including myocarditis, pericarditis and hypoglycaemia may be seen in infection by Plasmodium falciparum. However, these complications have rarely been reported with Plasmodium vivax infections. Myopericarditis complicating P. vivax malaria is particularly rare and only a few cases have been reported so far. We report on a case of myopericarditis due to P. vivax malaria to add to the literatur

Mathematical modeling of gonadotropin-releasing hormone signaling

Gonadotropin-releasing hormone (GnRH) acts via G-protein coupled receptors on pituitary gonadotropes to control reproduction. These are Gq-coupled receptors that mediate acute effects of GnRH on the exocytotic secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), as well as the chronic regulation of their synthesis. GnRH is secreted in short pulses and GnRH effects on its target cells are dependent upon the dynamics of these pulses. Here we overview GnRH receptors and their signaling network, placing emphasis on pulsatile signaling, and how mechanistic mathematical models and an information theoretic approach have helped further this field

Risk factors for early mortality in patients with pulmonary tuberculosis admitted to the emergency room.

Abstract Background and objectives Mortality of patients with pulmonary tuberculosis (TB) admitted to emergency departments is high. This study was aimed at analysing the risk factors associated with early mortality and designing a risk score based on simple parameters. Methods This prospective case-control study enrolled patients admitted to the emergency department of a referral TB hospital. Clinical, radiological, biochemical and microbiological risk factors associated with death were compared among patients dying within one week from admission (cases) and those surviving (controls). Results Forty-nine of 250 patients (19.6%) experienced early mortality. Multiple logistic regression analysis showed that oxygen saturation (SaO2) ≤90%, severe malnutrition, tachypnoea, tachycardia, hypotension, advanced disease at chest radiography, severe anaemia, hyponatremia, hypoproteinemia and hypercapnia were independently and significantly associated with early mortality. A clinical scoring system was further designed to stratify the risk of death by selecting five simple parameters (SpO2 ≤ 90%, tachypnoea, hypotension, advanced disease at chest radiography and tachycardia). This model predicted early mortality with a positive predictive value of 94.88% and a negative predictive value of 19.90%. Conclusions The scoring system based on simple parameters may help to refer severely ill patients early to a higher level to reduce mortality, improve success rates, minimise the need for pulmonary rehabilitation and prevent post-treatment sequelae

Effect of fertility levels and bioinoculants on growth, productivity and economics of cluster bean (Cyamopsis tetragonoloba)

A field experiment was conducted at research farm of SKN College of Agriculture, Jobner, Rajasthan to assess the effect of fertility and bioinoculants on growth, yield and economics of cluster bean (Cyamopsis tetragonoloba L.). The results revealed that application of 75% recommended dose of fertilizer along with Rhizobium inoculation recorded higher growth (plant height, branches/ plant, dry matter accumulation/plant and nodules/plant); yield attributes (pods/plant, seeds/pod and 1000-seed weight) seed and stover yields, gross returns (25.05 × 103 `/ha), net returns (13.63 × 103 `/ha) and B:C ratio (1.19) as compared to control and phosphate solubilizing bacteria (PSB) inoculation and remained at par with all other treatment combination. So, it was concluded that use of 75% RDF along with Rhizobium may be recommended for obtaining the higher yield of Cluster bean in the region

Electronic transport through carbon nanotubes -- effects of structural deformation and tube chirality

Atomistic simulations using a combination of classical forcefield and Density-Functional-Theory (DFT) show that carbon atoms remain essentially sp2 coordinated in either bent tubes or tubes pushed by an atomically sharp AFM tip. Subsequent Green's-function-based transport calculations reveal that for armchair tubes there is no significant drop in conductance, while for zigzag tubes the conductance can drop by several orders of magnitude in AFM-pushed tubes. The effect can be attributed to simple stretching of the tube under tip deformation, which opens up an energy gap at the Fermi surface.Comment: To appear in Physical Review Letter