323 research outputs found

    Evaluation of uterine cervix with transvaginal ultrasonography in women with threatened preterm labor and or preterm labor

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    Background: Preterm delivery can be associated with substantial perinatal morbidity and mortality. Nearly in 5 to 13% of pregnancies, happening deliveries are preterm before 37 weeks' gestation. Thus, prediction of preterm labor in parturient can provide a window of opportunity to prevent these complications and to be better prepared to deal with them. Hence the current study has been conducted with an objective to assess the efficiency of cervical length and funneling as assessed by transvaginal ultrasonography in predicting preterm labor.Methods: The current study was a prospective study, conducted in the Department of Obstetrics Emergencies, Dhanalakshmi Srinivasan Medical College and Hospital between November 2015 to April 2017. The study population included 60 women with singleton pregnancy of gestational age between 28 + 0 and 36 + 6 weeks and with painful and regular contractions (>1/10 min for at least 1 hour). Cervical length, funnelling length measured at presentation and after 48 hours were considered as predictor variables. The outcomes of interest were delivery within 1 week, delivery before 37 weeks and delivery before 34 weeks.Results: There was a statistically significant difference in cervical length and funnelling length between term and preterm groups at the time of diagnosis and after 48 hours (P <0.001). The positive predictive value increased from 33.3% to 100% with cervical length ≤ 40 mm to ≤ 20 mm. The negative predictive value decreased from 100% to 79.2% with cervical length ≤40 mm to ≤20 mm. To predict a preterm delivery in threatened preterm delivery patients, the sensitivity of a cervical length of ≤25 mm was 77.7%, specificity was 95.2%, the positive predictive value was 87.5% and negative predictive value is 90.9%.Conclusions: Cervical length and funnelling as assessed by transvaginal ultrasonography are efficient in predicting preterm labor

    STUDY ON IN VITRO CYTOTOXICITY OF PAPAIN AGAINST LIVER CANCER CELL LINE HEP G2

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    Objective: Cancer is a devastating public health problem all over the world. Herbal medicines have a vital role in the prevention and treatment of cancer. Papain is a proteolytic enzyme and a phyto therapeutic agent which highly appreciated in the medical field that prevents several chronic diseases such as cardiovascular disease, cancer and diabetes. The aim of the study describes about the cytotoxicity of papain against liver cancer cell line HepG2. Methods: In different concentrations of samples have been taken for cytotoxicity analysis using the MTT assay and calculate the percentage of cell viability. Results: The 50% inhibition concentration (IC50) of a sample was 125µg/ml and their cell viability percentage was 49.20. The 85% of cytotoxicity has been observed in 1000 µg/ml of papain against HepG2 cell line than other concentrations. Conclusion: 1000 µg/ml of papain has maximum (85%) cytotoxicity effect against liver cancer cell line hepG2

    ANALISIS MOTIVASI DAN DISIPLIN KERJA SERTA PENGARUHNYA TERHADAP PRESTASI KERJA KARYAWAN PADA CV. GRAHA INDAH SARI PALEMBANG

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    The purpose of this study was to determine the effect of motivation and discipline on employee performance in CV. Graha Indah Sari Palembang. The population in this study as many as 52 people. The sampling technique using saturated sampling technique, all populations sampled in the study. The data collection technique using a questionnaire. This research method using descriptive method with quantitative approach using a questionnaire as a data collection tool and use the technique multiple linear regression analysis to measure the impact of independent variables on the dependent variable is the motivation and discipline as an independent variable (X) and work performance of employees as the dependent variable (Y).The results showed : 1) Motivation and discipline have a positive and significant impact on employee performance in CV. Graha Indah Sari Palembang, 2) motivation has a positive and significant impact on employee performance in CV. Graha Indah Sari Palembang, and 3) Discipline of work has positive and significant impact on employee performance in CV. Graha Indah Sari Palembang. Keywords: motivation, work discipline and work performanc

    Study of recovery pattern of aphasia in stroke patients

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    Recovery pattern of thirty patients with aphasia were studied over a period of six months by measuring language performance at 4th week,8th week, 16th week and 24th week using tamil version of modified western aphasia battery in consultation with speech therapist and specialists. · Maximum recovery was noted in patients with transcortical motor aphasia and conduction aphasia. Out of three patients with conduction aphasia, two transformed into anomia. Patients with transcortical motor aphasia became normal. · Patients with broca’s aphasia showed fair recovery. Two patients out of nine evolved into transcortical motor aphasia. · Even though, global aphasia showed poor recovery, auditory word recognition was noted to improve. Three evolved into broca’s aphasia. · Among showing recovery groups, significant improvement was noted from 8th week of stroke. · Initial severity and final outcome correlated significantly. Patients with initial high scores indicating mild involvement improved better. · There was good correlation with the clinical –anatomical location of lesion and CT scan brain. The neurolinguistic aspect of the speech recovery in stroke patients and psychosocial aspects of stroke patients are further continued as an ongoing study in our hospital and are still under follow up as a continuation of the present study

    Effectiveness of Art Therapy on Stress among Patients with Cancer in a Selected Hospital, Thanjavur

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    A study to evaluate the effectiveness of Art Therapy on stress among patients with cancer at selected Hospital in Thanjavur District. The present study was conducted at Thanjavur cancer centre in Thanjavur. Pre experimental design with one group pre test and post test was used for this study. Permission was obtained from the hospital administrator and data collection was done over a period of 4 weeks. The investigator has selected 40 samples with cancer through convenience sampling technique. Oral consent was obtained from the subjects. In the pre test, 4 point stress assessment rating scale was used for assessing the level of stress. After the pretest, the investigator administered art therapy for 30-45 minutes for 5 consecutive days and then the post test was done after the 5 days of intervention. Descriptive and inferential statistics were used to analyze the findings of the study. There was a highly significant difference (P < 0.01) found between the mean pretest [48.05 (+6.95)] and post test score of stress [33.75 (+7.25)]. There was a significant association (P < 0.05) between the level of stress and age at P<0.05 level of significance. The findings of the study show that art therapy is effective in reducing the level of stress among patients with cancer. So, art therapy can be practiced in hospitals and in any set up to help patients and family members to cope up with stress and to promote stress free healthy life

    Immediate Effect of Acupuncture at Zusanli (ST-36) on Blood Pressure and Heart Rate Variability in Patients with Hypertension

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    BACKGROUND: Hypertension is defined as the persistent increase in arterial blood pressure, which causes large fatalities globally. Acupuncture is one of the traditional healing systems of medicine used to treat hypertension for centuries. zusanli (st-36) is a blood nourishing point. According to acupuncture concepts, it is used to reduce blood pressure. This study aimed to evaluate pressure-lowering effect of zusanli (st-36). OBJECTIVES: To evaluate the changes in blood pressure and heart rate variability immediately after the intervention. MATERIALS AND METHODS: This study was conducted on hundred hypertensive patients with anti-hypertensive medication, aged between 30-75 yrs. Hundred participants were randomized into 2 groups. The Study group underwent acupuncture at Zusanli (ST-36), and the control group underwent acupuncture at the sham point for 20 mins. Blood pressure and HRV were assessed before and immediately after the intervention. RESULTS: This study showed that acupuncture at Zusanli (ST-36) for 20 mins reduced SBP, DBP, and PP in study group. There was an increase in RR interval and HF in study group when compared with the control group. The other parameters of HRV variables have no change when compared with the control group. The reduction in blood pressure may be due to the enhancement of parasympathetic dominance in patients with hypertension. CONCLUSION: Acupuncture at Zusanli can be a cost-effective, adjuvant therapy for reducing blood pressure

    Gibbs energies of formation of rare earth oxysulfides

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    The standard Gibbs energy change accompanying the conversion of rare earth oxides to oxysulfides by reaction of rare earth oxides with diatomic sulfur gas has been measured in the temperature range 870 to 1300 K using the solid state cell: Pt/Cu+Cu2S/R2O2S+R2O3||(CaO)ZrO2||Ni+NiO, Pt where R=La, Nd, Sm, Gd, Tb, and Dy. The partial pressure of diatomic sulfur over a mixture of rare earth oxide (R2O3) and oxysulfide (R2O2S) is fixed by the dissociation of Cu2S to Cu in a closed system. The buffer mixture of Cu+Cu2S is physically separated from the rare earth oxide and oxysulfide to avoid complications arising from interaction between them. The corresponding equilibrium oxygen partial pressure is measured with an oxide solid electrolyte cell. Gibbs energy change for the conversion of oxide to the corresponding oxysulfide increases monotonically with atomic number of the rare earth element. Second law enthalpy of formation also shows a similar trend. Based on this empirical trend Gibbs energies of formation of oxysulfides of Pr, Eu, Ho, and Er are estimated as a function of temperature

    Standard free energies of formation of rare earth sesquisulphides

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    An e.m.f. technique is used for the measurement of the Gibbs' energy changes involved in the conversion of the rare earth oxysulphides to the corresponding sesquisulphides in the temperature range 870 to 1120 K. The cell arrangement is Au, Ag + Ag2S|R2O2S + R2S3|| (Y2O3)ThO2|| Fe + Fe0.95O, Au where R = La, Pr, Nd, Sm, Eu and Gd. Yttria-doped thoria is used as the solid electrolyte because it has predominant ionic conduction at the low oxygen potentials developed at the R2O2S + R2S3 electrode, especially for systems containing heavier rare earth elements. The sulphur potential at the left-hand electrode is established by the dissociation of Ag2S to silver in a closed system. The changes in the standard free energy, enthalpy and entropy associated with the conversion of the rare earth oxysulphide to the sesquisulphide all show a smooth variation with rare earth atomic number. Based on these empirical trends, the corresponding thermodynamic functions for terbium, dysprosium and holmium systems are estimated. The measured free energy values are combined with recent data on the standard free energies of formation of the rare earth oxysulphides to obtain the Gibbs' energies of formation of the corresponding sesquisulphides

    Influence and comparison of thermal, ultrasonic and thermosonic treatments on physicochemical quality of orange juice

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    Orange juice is the most popular and consumed juice worldwide, associated with healthy eating habits. Thermal pasteurization treatments are used to preserve industrially produced juice. Unfortunately, this process removes many nutritious compounds. Therefore, other milder treatments are being studied to minimize the impact on the product's final quality. The main goal of this study was to evaluate the effect of thermosonication (TS) treatment on the quality of orange juice in comparison with heat (HT) and ultrasound (UT) treatments alone. Commercial pasteurized orange juice was treated by UT, HT or TS in a sonoreactor (20 kHz and 80% amplitude) at different temperatures 20, 30, 40, 50 and 60 °C for 90, 60, 60, 30 and 30 min, respectively. These treatment times were chosen to guarantee the Staphylococcus aureus inactivation. Physicochemical characteristics, such as pH, colour and Brix, and microbial cell counts, were evaluated before and after treatments. Principal components analysis (PCA) was carried out to detect simple patterns and differences.All treatments could reduce the S. aureus presence in at least 3 log cycles, except the HT at 20, 30 and 40 °C, where an increase in microbial counts was attained. The majority of quality characteristics were not significantly affected by the applied treatments, except a* value for US 20, 30 40 and 50°C, Brix for TS 60°C and pH for US 30 and 40 °C, TS 50°C and HT 20 and 50 °C. PCA revealed two components with eigenvalues greater than one, which explained 56.1% and 28.4% of the total variance, respectively. The first component was mostly influenced by a*, pH, L*, b* and Chroma, while the second by Hue and microbial inactivation. The second component allowed a clear distinction between types of treatment, while the first component allowed separation among the processing conditions of temperature/time.info:eu-repo/semantics/publishedVersio
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